Results 131 to 140 of about 53,609 (266)
目的: 研究 c -erbB-2, c-erbB-4 原癌基因过度表达与乳腺癌发生及其病理参数的相关关系。方法: 对 122 例乳腺疾病石蜡切块,其 中 80 例乳腺癌, 16 例乳腺纤维腺瘤, 9 例乳腺纤维囊性病, 17 例乳腺癌转移淋巴结均采用免疫组化( LSAB 法)结合计算机图象分析研究原癌 基因产物 c-erbB-2, c-erbB-4的表达情况。结果: c-erbB-2 在乳腺癌中存在过度表达, P
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p53、bcl-2和c-erbB-2在恶性卵巢上皮性肿瘤中的表达及临床意义
目的检测62例恶性卵巢上皮性肿瘤中p53、bcl-2和c-erbB-2的表达情况以探讨三种基因对恶性卵巢上皮性肿瘤的早期诊断及预后判断的意义。方法采用免疫组织化学方法检测p53b、cl-2 and c-erbB-2在恶性卵巢上皮性肿瘤中的表达及其与组织学分类,临床分期,腹水,淋巴结转移预后的关系。结果恶性卵巢上皮性肿瘤在p53、bcl-2 and c-erbB-2的表达阳性率分别52.23%,62.90%和45.16%与卵巢瘤组和正常组之间比较差异有显著性 ...
许天敏, 崔满华, 林杨, 何凯
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No significant predictive value of c- erbB-2 or p53 expression regarding sensitivity to primary chemotherapy or radiotherapy in breast cancer [PDF]
S Rozan +11 more
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Platinum‐resistant patients exhibited ascites suffer from immune exhaustion and enriched in lipids, which is used by tumor cells as energy resources to counteract platinum damage through active macropinocytosis and lipid catabolism. These resistant features in ascites can also predict, to a certain extent, the efficacy of platinum‐based therapy in ...
Ruiqi Zheng +12 more
wiley +1 more source
CONTEXT AND OBJECTIVE: Breast cancer is thought to derive from progressively aberrant, non-invasive breast lesions, but it is not known exactly how invasive breast cancer develops from these lesions.
Marcus Vinicius Martins de Menezes +7 more
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MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential
The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman +7 more
wiley +1 more source
New treatments for breast cancer: Breakthroughs for patient care or just steps in the right direction? [PDF]
Three areas of clinical research in breast cancer treatment led to news breaking presentations at the American Society of Clinical Oncology (ASCO) meeting, 1998, in Los Angeles.
Castiglione-Gertsch, M. +3 more
core
ABSTRACT MicroRNAs (miRNAs) have been shown to regulate many cellular processes and to play a role in host‐pathogen interactions. However, the role of miRNA in urinary tract infection (UTI) remains unclear. The aim of this study was to analyze and compare miRNAs from supernatants of human bladder epithelial cells infected with ESBL‐producing (ESBL019 ...
Katarina Persson +3 more
wiley +1 more source
An immunohistochemical study of the c-erbB-2 oncogene product in intraductal mucin-hypersecreting neoplasms and in ductal cell carcinomas of the pancreas [PDF]
Kennichi Satoh +9 more
openalex +1 more source

