Results 71 to 80 of about 112,287,737 (220)

CMBs carrying PTX and CRISPR/Cas9 targeting C‑erbB‑2 plasmids interfere with endometrial cancer cells. [PDF]

Mol Med Rep, 2021
Peng S, Cai J, Bao S.
europepmc   +1 more source

Phase II Study of Cisplatin/Gemcitabine Plus Necitumumab for Squamous NSCLC After ICI‐Platinum Therapy (WJOG14120L)

Cancer Science, EarlyView.
WJOG14120L NESSIE evaluated cisplatin, gemcitabine, and necitumumab (CGN) as second‐line therapy after ICI‐based treatment in 46 patients with advanced squamous NSCLC. ORR was 26.1%, DCR 87.0%, and median PFS 4.4 months. Although the predefined ORR threshold was not met, CGN showed modest antitumor activity with manageable toxicity.
Hiroshige Yoshioka, Keita Mori, Nobuhisa Ishikawa, Hiroaki Kanemura, Koichi Azuma, Yukihiro Toi, Hiroshi Handa, Yosuke Tamura, Hiroaki Akamatsu, Haruko Daga, Masafumi Yamaguchi, Teppei Yamaguchi, Yuki Sato, Nobuyuki Yamamoto, Kazuhiko Nakagawa, Takayasu Kurata   +15 more
wiley   +1 more source

C-erbB-2 mRNA in breast cancer specimens that exhibit membrane or cytoplasmic immunoreactivity for c-erbB-2.

Oncology research, 2000
Immunocytochemically detected membrane staining for c-erbB-2 in 20-30% of breast cancers correlates with a poorer prognosis for the patients. However, cytoplasmic immunoreactivity for c-erbB-2 has also been found in some specimens using some particular antisera, and it has been suggested that this staining arises from a protein located in the ...
S L, Taylor, P S, Rudland, R, Barraclough   +2 more
openaire   +1 more source

Is there a relationship between c-erbB-1 and c-erbB-2 amplification and protein overexpression in NSCLC?

, 2005
In order to analyse the genetic abnormalities and protein expression of c-erbB-1 and -2, we have performed fluorescence in situ hybridisation (FISH) and immunohistochemistry (IHC) in resected non-small cell lung carcinoma (NSCLC).
Sculier, Jean-Paul, Meert, Anne-Pascale, Martin, Benoît, Verdebout, Jean-Marc, Noel, Sophie, Ninane, Vincent   +5 more
core   +1 more source

Marcadores moleculares associados ao câncer de mama não metástico

Revista Brasileira de Cancerologia, 2002
O câncer de mama é considerado a mais freqüente neoplasia que acomete mulheres em todo o mundo. No Brasil, representa a primeira neoplasia em incidência na mulher, sendo que a maioria dos casos relatados encontra-se na região Sul (67%).
Daniela de Melo e Silva, Vera Aparecida Saddi, Euza Guimarães Momotuk   +2 more
doaj   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Maternal obesity during lactation as a hypertensive cardiovascular risk factor in the offspring

Experimental Physiology, EarlyView.
Abstract Maternal obesity is a major public health concern, with growing evidence supporting its role in the developmental programming of cardiometabolic disease. Although prenatal mechanisms have been investigated extensively, the contribution of lactation as a postnatal window of cardiovascular (CV) programming remains insufficiently understood ...
Gabriela Arenas, Cristián A. Amador, Susana Contreras‐Duarte   +2 more
wiley   +1 more source

C-erbB-2 expression does not predict response to docetaxel or sequential methotrexate and 5-fluorouracil in advanced breast cancer

, 2002
Breast cancer patients with c-erbB-2-positive tumours seem to benefit from anthracycline-based adjuvant chemotherapy. The predictive value of c-erbB-2 for taxane sensitivity is not yet clear.
Bergh, J, J Bergh, Malmström, Per,, N.-O Bengtsson, Blomqvist, C, Saksela, E, J Sjöström, J Collan, C Blomqvist, K von Boguslawski, K Franssila, Mjaaland, I, Skiold-Petterson, D, Valvere, V, Bengtsson, NO, I Mjaaland, E Wist, Wist, E, Ostenstad, B, V Valvere, B Østenstad, D Skiöld-Petterson, E Saksela, Franssila, K, von Boguslawski, K, P Malmström, Collan, J, Lund University., von, Boguslawski K, Sjöström, J, Malmström, P   +30 more
core   +1 more source

Assessment of staging, prognosis and mortality of colorectal cancer by tumor markers: receptor erbB-2 and cadherins

Acta Cirúrgica Brasileira, 2005
PURPOSE: To evaluate the prognostic significance and correlation with staging and degree of cell differentiation of the tumoral expression of the proteins c-erbB-2 and E-cadherin, in patients with colorectal adenocarcinoma.
Jesus Eliane C., Matos Delcio, Artigiani Ricardo, Waitzberg Angela F.L., Goldenberg Alberto, Saad Sarhan Sydney   +5 more
doaj  

Impact of Molecular Alterations on Survival in Biliary Tract Cancers: A Retrospective Belgian Cohort Study

International Journal of Cancer, Volume 160, Issue 1, Page 201-215, 1 January 2027.
ABSTRACT Biliary tract cancers (BTCs) are aggressive malignancies associated with a poor prognosis. Although molecular profiling is recommended to guide therapeutic decision‐making, real‐practice data on the prevalence and prognostic significance of genomic alterations in European BTC cohorts remain limited.
Jorine Arnouts, Léon C. van Kempen, Senada Koljenović, Helena Oliveres, Pieterjan Vanclooster, Hans Prenen, Caro De Weerdt, Siddharth Chhajlani, Geert Roeyen, Laure Sorber, Koen De Winne, Jonas Dahnoun, Greetje Vanhoutte, Timon Vandamme, Karen Zwaenepoel   +14 more
wiley   +1 more source