Results 81 to 90 of about 43,518 (188)

Protein expression of c-erbB-2 and p53 in normal ducts, ductal carcinoma in situ and invasive carcinoma of the same breast

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVE: Breast cancer is thought to derive from progressively aberrant, non-invasive breast lesions, but it is not known exactly how invasive breast cancer develops from these lesions.
Marcus Vinicius Martins de Menezes   +7 more
doaj   +1 more source

EPİTELYAL OVER TÜMÖRLERİ İLE bcl-2, nm 23 ve c-erbB-2 EKSPRESYONLARI ARASINDAKİ İLİŞKİ

open access: yesCerrahpaşa Medical Journal, 2019
Background and Design.- Ovarian cancer is the most common cause of death among all gynecologic malignancies. Genetic alterations important in ovarian tumorigenesis have been identified recently.
Sermin ÖZKAL   +5 more
doaj  

c-erbB-2 expression and nuclear pleomorphism in canine mammary tumors

open access: yesBrazilian Journal of Medical and Biological Research, 2004
The objective of the present investigation was to study the expression of c-erbB-2 and MIB-1 and try to associate them with morphological features of the cell such as nuclear pleomorphism, mitotic count and histological grade in a series of 70 canine ...
Dutra A.P.   +3 more
doaj  

Advanced hybrid dielectric OTFT biosensor for early breast cancer diagnosis with enhanced sensitivity

open access: yesResults in Engineering
This research work presents an innovative charge-modulated hybrid dielectric organic thin-film transistor (CM-HD OTFT) biosensor designed for the early detection of the breast cancer biomarker C-erbB-2 in saliva and serum samples. By incorporating a dual-
L. Prasanthi   +6 more
doaj   +1 more source

胃癌p53、c-erbB-2、p21、nm23基因表达的分布特点及其临床意义

open access: yesZhongguo shiyan zhenduanxue, 2005
目的为探讨手术切除胃癌组织p53、c-erbB-2、p21、nm23联合基因产物表达检测对胃癌诊断治疗及预后判断的价值。方法应用免疫组化技术检测了手术切除胃癌组织p53c、-erbB-2、p21、nm23基因产物表达。结果p53蛋白表达阳性率为36.4%46.7%,c-erbB-2为33.3%56.8%,p21为35.1%56.7%,nm23为30.0%70.5%。在非胃癌组织中(胃,十二指肠溃疡,胃息肉,重度不典型增生)未见c-erbB-2、p21、nm23基因表达。p53c、-erbB-2 ...
陈永胜   +4 more
doaj  

子宫内膜癌中Glut-1、C-erbB-2表达及其相互关系

open access: yesZhongguo shiyan zhenduanxue, 2009
目的探讨C-erbB-2和葡萄糖转运蛋白1(Glut-1)在不典型增生子宫内膜和子宫内膜腺癌中的表达特点及其相互关系。方法应用免疫组织化学方法检测Glut-1、C-erbB-2在30例正常增生期子宫内膜、32例不典型增生子宫内膜和35例子宫内膜腺癌中的表达,并结合临床资料进行分析。结果Glut-1、C-erbB-2在各组中的阳性表达率增生期子宫内膜均为0,不典型增生组分别为46.9%和59.4%,子宫内膜腺癌组82.9%,74.3%;二者在各试验组间均有显著差异 ...
张颖, 陈海玲
doaj  

Evaluation of the expression of the oncogen C-ERBB-2/HER2 in advanced gastric cancer cases from Costa Rica. [PDF]

open access: yesEcancermedicalscience, 2019
Cordero-García E   +4 more
europepmc   +1 more source

胃肿瘤中EGFR、C-erbB-2和PCNA的表达及其临床意义

open access: yesZhongguo shiyan zhenduanxue, 2011
目的探讨表皮生长因子受体(EGFR)、原癌基因(C-erbB-2)及增殖细胞核抗原(PCNA)在胃肿瘤中的表达,研究其在肿瘤发展中的作用。方法采用免疫组化SABC法、检测30例手术切除的胃癌实质组织中EGFR、C-erbB-2、PCNA的表达,与15例正常胃组织相对照,并对三者的相关性因素进行分析,探讨三者在胃癌检验中的作用和价值。结果 EGFR、C-erbB-2和PCNA在胃癌组织中的阳性表达显著高于正常胃组织 ...
马健
doaj  

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