Results 81 to 90 of about 112,287,737 (220)

Personality correlates of P53, c-erbB-2, BRCA1 protein expression in breast cancer patients

open access: yes, 2004
In this work, the associations between personality trait and gene protein expressions were evaluated in seventy women with breast cancer. The personality traits of these patients were examined with the Eysenck Personality Questionnaire (EPQ) before ...
W. J. Lin, J. P. Liu, Y. Liu
core  

SURFACE DISTRIBUTION AND INTERNALIZATION OF ERBB-2 PROTEINS

open access: yes, 1992
We report the localization over the cell surface and the early steps of antibody-induced internalization of the product of the erbB-2 proto-oncogene, structurally related to the epidermal growth factor receptor (EGFR).
FRATI, Luigi   +4 more
core   +1 more source

Evaluation of C-ErbB-2 Overexpression and Her-2/neu Gene Copy Number Heterogeneity in Barrett’s Adenocarcinoma

open access: yesAnalytical Cellular Pathology, 2000
Amplifiction of the Her-2/neu gene is accompanied by overexpression of its cell surface receptor product, c‐erbB‐2 protein. To investigate the degree of intratumoural heterogeneity we applied immunohistochemistry in primary Barrett’s adenocarcinoma (BCA)
Axel Walch   +8 more
doaj   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

open access: yesComputational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman   +2 more
wiley   +1 more source

Kolorektal kanser ve kolorektal prekanseröz adenom olgularında c-erbB-2 ve c-erbB-3 reseptör ekspresyonunun değerlendirilmesi

open access: yes, 2003
76 ÖZET Tümör oluşumunun en mükemmel modeli kolorektal kanser gelişimidir. Kolon kanser oluşumunda pek çok genetik ve epigenerik değişiklikler tespit edilmiştir. Ancak kolorektal kan serler halen tüm dünyada mortaliteye neden olan 4. kanserdir.
FATMA AYERDEN EBİNÇ
core  

Relationship between XRCC1 protein, miR-7, c-erbB-2 gene expression levels and radiotherapy resistance in non-small cell lung cancer

open access: yesZhongguo linchuang yanjiu
Objective To analyze the relationship between XRCC1 protein, miR-7, c-erbB-2 gene expression and radiotherapy resistance in non-small cell lung cancer (NSCLC) and their predictive value.
MA Tingting, ZHOU Liqing, SU Xinyu, XIA Jianhong, YAN Yan
doaj   +1 more source

In vitro study on human cytomegalovirus affecting early pregnancy villous EVT's invasion function

open access: yesVirology Journal, 2011
Background Human cytomegalovirus (HCMV) is the most common pathogen in uterus during pregnancy, which may lead to some serious results such as miscarriage, stillbirth, cerebellar malformation, fetus developmental retardation, but its pathogenesis has not
Juan Xiao   +5 more
doaj   +1 more source

A transition zone enriched WIF1+ basal cell subtype is associated with benign prostatic hyperplasia

open access: yesThe Journal of Pathology, Volume 270, Issue 4, Page 481-496, December 2026.
Abstract The cellular composition and disease susceptibilities of the distinct zones of the human prostate remain incompletely understood. Benign prostatic hyperplasia (BPH) is a common condition that causes widespread morbidity and is nearly exclusively localized to the transition zone (TZ).
Rulin Wang   +20 more
wiley   +1 more source

Significance of immunohistochemical c-ErbB-2 product localisation pattern for prognosis in human breast cancer

open access: yes, 2001
Breast cancer is an increasingly important cause of illness and death among women. In recent years several novel prognostic determinants of breast cancer have been identified, including c-ErbB-2.
Kayani, Naila   +11 more
core   +1 more source

C/EBPbeta-2 confers EGF-independent growth and disrupts the normal acinar architecture of human mammary epithelial cells

open access: yesMolecular Cancer, 2005
Background The transcription factor, C/EBPbeta, is a key regulator of growth and differentiation in the mammary gland. There are three different protein isoforms of C/EBPbeta. C/EBPbeta-1 and -2 are transactivators, and differ by only 23 N-terminal amino
Sealy Linda, Wells Sam, Bundy Linda
doaj   +1 more source

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