Tracking C–H activation with orbital resolution [PDF]
Science, 2023 Transition metal reactivity toward carbon–hydrogen (C–H) bonds hinges on the interplay of electron donation and withdrawal at the metal center. Manipulating this reactivity in a controlled way is difficult because the hypothesized metal-alkane charge-transfer interactions are challenging to access experimentally. Using time-resolved x-ray spectroscopy,
Raphael M. Jay +23 more
openaire +4 more sources
Tandem C–O and C–H Activation at Palladium Enables Catalytic Direct C–H Alkenylation with Enol Pivalates [PDF]
, 2021 The use of oxygen-based electrophiles in cross-coupling remains challenging for substrates with strong C–O bonds, with few examples that can combine C–O activation with an-other strong-bond activation in tandem.
Nahiane, Pipaon Fernandez +4 more
core +2 more sources
Transition Metal-catalyzed C-H /C-C Activation and Coupling with 1, 3-diyne [PDF]
, 2022 This review focuses on providing a broad overview of the recent developments in the field of transition metal-catalyzed C-H bond activation and coupling with 1,3-diyne for assembling alkynylated heterocycles and bis-heterocycles.
Tanmayee, Nanda +4 more
core +1 more source
δ-C(sp3)H Activation of Free Alcohols Enabled by Rationally Designed H-Bond-Acceptor Ligands [PDF]
, 2023 The ability to employ a wide range of native substrates is essential for the broad application of transition-metal-catalyzed C–H activation. Recent advances have made native carboxylic acids, ketones, and amines amenable to C(sp3)–H activation, but ...
Jin-Quan, Yu +4 more
core +2 more sources
C—H Activation of Unbiased C(sp3)—H Bonds [PDF]
, 2022 The selective functionalization of non-activated C(sp3)—H bonds is a major challenge in chemistry. Here, we have developed an [Au]-catalyzed C(sp3)-H activation of common 1 bromoalkynes into a library of diverse 3D-scaffolds.
Pablo, Barrio +6 more
core +2 more sources
Twofold C-H Activation-Based Enantio- and Diastereoselective C-H Arylation Using Diarylacetylenes as Rare Arylating Reagents [PDF]
, 2021 C-H bond activation has been established as an attractive strategy to access axially chiral biaryls, and the most straightforward method is direct C-H arylation of arenes.
Xingwei, Li +4 more
core +2 more sources
When transition-metal-catalyzed C–H activation meets allene chemistry
Tetrahedron Chem, 2023 Transition-metal-catalyzed allenes-involved C–H functionalizations demonstrate unique selectivity and undergo exceptional pathways due to the existence of elusive orthogonal cumulative CCC bonds.
Shu-Meng Deng +2 more
doaj +1 more source
Accessing Metal-Specific Orbital Interactions in C-H Activation using Resonant Inelastic X-ray Scattering [PDF]
, 2023 Photochemically prepared transition-metal complexes are known to be effective at cleaving the strong C-H bonds of organic molecules in room temperature solutions.
Dmitry, Ozerov +19 more
core +2 more sources
Functionalization of Porphyrins Using Metal-Catalyzed C–H Activation
Inorganics, 2022 The review is devoted to the C–H functionalization of porphyrins. Porphyrins exhibit the properties of organic semiconductors, light energy converters, chemical and electrochemical catalysts, and photocatalysts.
Aleksey N. Kiselev +3 more
doaj +1 more source
Molecules, 2021 Rollover cyclometalation constitutes a particular case of cyclometallation reaction. This reaction occurs when a chelated heterocyclic ligand loses its bidentate coordination mode and undergoes an internal rotation, after which a remote C–H bond is ...
Antonio Zucca, Maria I. Pilo
doaj +1 more source