Results 51 to 60 of about 29,655,632 (304)
Cobalt-catalyzed nucleophilic addition of the allylic C(sp3)–H bond of simple alkenes to ketones
We herein describe a cobalt/Xantphos-catalyzed regioselective addition of simple alkenes to acetophenone derivatives, affording branched homoallylic alcohols in high yields with perfect branch selectivities.
Tsuyoshi Mita +3 more
doaj +1 more source
Catalytic Asymmetric Functionalization of Inert Bonds and Synthesis of Bioactive Natural Products
The direct and enantioselective functionalization of inert bonds such as carbon–hydrogen and carbon–carbon is an emerging tool towards more sustainable and efficient synthetic methods.
Nicolai Cramer
doaj +1 more source
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Phenylacetylene and Carbon Dioxide Activation by an Organometallic Samarium Complex
Small molecule activation is a topic of growing importance and the use of low-valent f-elements to perform these reactions is nowadays well established.
Violaine Goudy +6 more
doaj +1 more source
Manganese(I)‐Catalyzed Dispersion‐Enabled C−H/C−C Activation
C-H/C-C Functionalizations were achieved with the aid of a versatile manganese(I) catalyst. Thus, an organometallic manganese-catalyzed C-H activation set the stage for silver-free C-H/C-C transformations with ample substrate scope and excellent levels ...
Mata, Ricardo A. +11 more
core +1 more source
Exploiting Chemical Diversity through C–H Activation and DNA-Encoding [PDF]
DNA-encoded library (DEL) technology has the potential to dramatically expedite hit identification in drug discovery owing to its ability to perform protein affinity selection with millions or billions of molecules in a single experiment.
Zhe, Zhuang +13 more
core +2 more sources
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Electrochemical Cobalt‐Catalyzed C−H Activation
AbstractCarbon–heteroatom bonds represent omnipresent structural motifs of the vast majority of functionalized materials and bioactive compounds. C−H activation has emerged as arguably the most efficient strategy to construct C−Het bonds. Despite of major advances, these C−H transformations were largely dominated by precious transition metal catalysts,
Nicolas Sauermann +2 more
openaire +3 more sources
Natural Product Synthesis by C-H Activation
The widespread use of transition-metal-mediated C-H bond activation has altered the field of organic synthesis. Notwithstanding the immense effect this strategy has had on classical organic reactions, the applications of this methodology extend further ...
MAITI, D, SINHA, SK, ZANONI, G
core +1 more source
Dual Catalytic C(sp2)–H Activation of Azaheterocycles towards C–N Atropisomers [PDF]
We describe a PdII-catalyzed enantioselective C(heteroaryl)–H activation method enabled by a chiral transient directing group (cTDG) to gain access to C–N atropisomers.
Quynh, Wong +5 more
core +2 more sources

