Results 51 to 60 of about 2,467,830 (354)
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
Phenylacetylene and Carbon Dioxide Activation by an Organometallic Samarium Complex
Small molecule activation is a topic of growing importance and the use of low-valent f-elements to perform these reactions is nowadays well established.
Violaine Goudy +6 more
doaj +1 more source
Computational exploration of the reaction mechanism of the Cu+-catalysed synthesis of indoles from N-aryl enaminones [PDF]
We have studied the role of Cu+-phenantroline as a catalyst in the cyclization of N-aryl-enaminones using density-functional theory computations. The catalyst was found to bind the substrate upon deprotonation of its eneaminone, and to dramatically ...
Carlos E. P. Bernardo, Pedro J. Silva
doaj +1 more source
Manganese(I)‐Catalyzed Dispersion‐Enabled C−H/C−C Activation
C-H/C-C Functionalizations were achieved with the aid of a versatile manganese(I) catalyst. Thus, an organometallic manganese-catalyzed C-H activation set the stage for silver-free C-H/C-C transformations with ample substrate scope and excellent levels ...
Mata, Ricardo A. +11 more
core +1 more source
In Silico Rationalisation of Selectivity and Reactivity in Pd-Catalysed C-H Activation Reactions
A computational approach has been developed to automatically generate and analyse the structures of the intermediates of palladium catalysed carbon-hydrogen (C-H) activation reactions as well as to predict the final products.
Steve, Ley +3 more
core +1 more source
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
Natural Product Synthesis by C-H Activation
The widespread use of transition-metal-mediated C-H bond activation has altered the field of organic synthesis. Notwithstanding the immense effect this strategy has had on classical organic reactions, the applications of this methodology extend further ...
MAITI, D, SINHA, SK, ZANONI, G
core +1 more source
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
meta- and para-Selective C–H Functionalization by C–H Activation
Transition metal-catalyzed C–H bond functionalization has recently emerged as an indispensable tool for transforming otherwise unreactive C–H bonds. In addition to various strategies for ortho-selective functionalization via chelation assistance, organometallic C–H activation has recently enabled novel functionalizations of (hetero)arenes at remote ...
Li, Jie +2 more
openaire +2 more sources
Electrocatalytic C–H Activation
C–H activation has emerged as a transformative tool in molecular synthesis, but until recently oxidative C–H activations have largely involved the use of stoichiometric amounts of expensive and toxic metal oxidants, compromising the overall sustainable nature of C–H activation chemistry.
Nicolas Sauermann +3 more
openaire +2 more sources

