Results 61 to 70 of about 31,423,583 (299)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh +4 more
wiley +1 more source
Electrochemical Cobalt‐Catalyzed C−H Activation
Chemistry – A European Journal, 2018 AbstractCarbon–heteroatom bonds represent omnipresent structural motifs of the vast majority of functionalized materials and bioactive compounds. C−H activation has emerged as arguably the most efficient strategy to construct C−Het bonds. Despite of major advances, these C−H transformations were largely dominated by precious transition metal catalysts,
Nicolas Sauermann +2 more
openaire +3 more sources
, 2019 Chiral rhodium(III) cyclopentadienyl catalysts ((CpRhIII)-Rh-X) play significant roles in asymmetric arene C-H activation. Rh/Ir-catalyzed couplings of arenes and strained rings have been well-studied, but they have been limited to racemic systems ...
Yang, Xifa, Zheng, Guangfan, Li, Xingwei
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques +5 more
wiley +1 more source
A Personal Account on Industrial Collaborations in the Field of C–H Activation
CHIMIA, 2021 In recent years, transition-metal-catalyzed C–H functionalization has emerged as a potentially greener alternative to classic cross-couplings and as a powerful tool to access complex functional molecules with improved step-economy.
Olivier Baudoin
doaj +1 more source
Intermolecular Radical C–H Bond Activation: A Powerful Tool for Late Stage Functionalization
CHIMIA, 2020 The synthesis of complex molecules via radical reactions involving carbon–carbon and carbon–heteroatom bonds has become a very successful approach. Radical chemistry has long been dominated by the use of tin-based reagents.
Fabrice Dénès
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim +11 more
wiley +1 more source
Deuteration of Arenes via Pd-Catalyzed C–H Activation – A Lesson in Nondirected C–H Activation, Isotopic Labelling and NMR Characterization [PDF]
Isotopic labelling is an important tool in medicinal research, metabolomics, and for understanding reaction mechanisms. In this context, transition metal catalyzed C–H activation has emerged as a key technology for deuterium incorporation via hydrogen ...
Fritz, Deufel, Manuel, van Gemmeren
core +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Metal Nanoparticles as Sustainable Tools for C–N Bond Formation via C–H Activation
Molecules, 2021 The design of highly active metal nanoparticles to be employed as efficient heterogeneous catalysts is a key tool for the construction of complex organic molecules and the minimization of their environmental costs.
Federica Valentini +2 more
doaj +1 more source