Results 81 to 90 of about 3,879,991 (283)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Stereoselective Radical Translocations

CHIMIA, 2008
The stereochemical outcome of intramolecular radical mediated hydrogen transfer (= radical translocation) is discussed. Low to excellent levels of stereocontrol are observed making such processes attractive for applications in target-oriented ...
Philippe Renaud, Florent Beaufils, Fabrice Dénès, Laurence Feray, Christoph Imboden, Nikolai Kuznetsov   +5 more
doaj   +1 more source

Issues Relevant to C-H Activation at Platinum(II): Comparative Studies between Cationic, Zwitterionic, and Neutral Platinum(II) Compounds in Benzene Solution [PDF]

, 2004
Cationic late metal systems are being highly scrutinized due to their propensity to mediate so-called electrophilic C-H activation reactions. This contribution compares the reactivity of highly reactive cationic platinum(II) systems with structurally
Betley, Theodore A., Peters, Jonas C., Thomas, Christine M., Thomas, J. Christopher   +3 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Robotic Lepidoptery: Structural Characterization of (mostly) Unexpected Palladium Complexes Obtained from High-Throughput Catalyst Screening [PDF]

, 2009
In the course of a high-throughput search for optimal combinations of bidentate ligands with Pd(II) carboxylates to generate oxidation catalysts, we obtained and crystallographically characterized a number of crystalline products. While some combinations
Bercaw, John E., Day, Michael W., Golisz, Suzanne R., Hazari, Nilay, Henling, Lawrence M., Labinger, Jay A., Schofer, Susan J., Virgil, Scott   +7 more
core   +1 more source

Heterolytic Bond Activation at Gold: Evidence for Gold(III) H-B, H-Si Complexes, H-H and H-C Cleavage [PDF]

, 2019
The coordinatively unsaturated gold(III) chelate complex [(C^N-CH)Au(C6F5)]+ (1+) reacts with main group hydrides H-BPin and H-SiEt3 in dichloromethane solution at 70 °C to form the corresponding σ-complexes, which were spectroscopically characterized (C^
Beckett, Bertrand, Bhattacharjee, Blons, Bommer, Bus, Cardenas-Lizana, Carr, Chen, Claus, Comas-Vives, Comas-Vives, Corey, Corma, Corma, Corma, Corma, Debono, Dobrott, Fiorio, Fiorio, Fürstner, Hashmi, Hertz, Hierso, Hopkinson, Joost, Joost, Keane, Kidonakis, Lancaster, Leyva, Leyva-Pérez, Li, Lv, Malta, Manzoli, McEwan, Miró, Nuss, Ohnishi, Pan, Pan, Raubenheimer, Rocchigiani, Rocchigiani, Rocchigiani, Rocchigiani, Roşca, Saridakis, Satoh, Schmidbaur, Serna, Silverwood, Stephan, Takale, Vilhanova, Yang, Zou   +58 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Benzene C−H Bond Activation in Carboxylic Acids Catalyzed by O-Donor Iridium(III) Complexes: An Experimental and Density Functional Study [PDF]

, 2010
The mechanism of benzene C−H bond activation by [Ir(μ-acac-O,O,C^3)(acac-O,O)(OAc)]_2 (4) and [Ir(μ-acac-O,O,C^3)(acac-O,O)(TFA)]_2 (5) complexes (acac = acetylacetonato, OAc = acetate, and TFA = trifluoroacetate) was studied experimentally and ...
Bhalla, Gaurav, Bischof, Steven M., Ess, Daniel H., Goddard, William A., III, Meier, Steven K., Nielsen, Robert J., Oxgaard, Jonas, Periana, Roy A.   +7 more
core   +1 more source