Results 131 to 140 of about 43,345 (260)

Remote CH Bond Functionalizations

, 2023
Korvorapun, Korkit, Samanta, Ramesh C., Rogge, Torben, Ackermann, Lutz, Maiti, Debabrata, Guin, Srimanta   +5 more
openaire   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Lewis Base-Enhanced C-H Bond Functionalization Mediated by a Diiron Imido Complex. [PDF]

Inorg Chem
Gwinn RK, Latendresse TP, Beck ON, Slebodnick C, Mayhall NJ, Casaday CE, Thornton DA.   +6 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Unlocking Terpenoid Transformations: C-H Bond Functionalization for Methyl Group Substitution, Elimination, and Integration. [PDF]

ACS Cent Sci
Murray LAM.
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Substitution, Elimination, and Integration of Methyl Groups in Terpenes Initiated by C-H Bond Functionalization. [PDF]

ACS Cent Sci
Kang YC, Wetterer RT, Karimov RR, Kojima M, Surke M, Martín-Torres I, Nicolai J, Elkin M, Hartwig JF.   +8 more
europepmc   +1 more source

Palladium-catalyzed direct asymmetric C-H bond functionalization enabled by the directing group strategy. [PDF]

Chem Sci, 2020
Yang K, Song M, Liu H, Ge H.
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Connecting remote C-H bond functionalization and decarboxylative coupling using simple amines. [PDF]

Nat Chem, 2020
de Azambuja F, Yang MH, Feoktistova T, Selvaraju M, Brueckner AC, Grove MA, Koley S, Cheong PH, Altman RA.   +8 more
europepmc   +1 more source