Results 51 to 60 of about 105,861 (299)
Intermolecular Radical C–H Bond Activation: A Powerful Tool for Late Stage Functionalization
CHIMIA, 2020 The synthesis of complex molecules via radical reactions involving carbon–carbon and carbon–heteroatom bonds has become a very successful approach. Radical chemistry has long been dominated by the use of tin-based reagents.
Fabrice Dénès
doaj +1 more source
Intramolecular Arene C−H to C−P Functionalization Mediated by Nickel(II) and Palladium(II) [PDF]
, 2013 A tris(phosphine) ligand with a triarylbenzene backbone was employed to support mono-nickel(II) and -palladium(II) complexes. Two phosphine arms coordinated to the metal center, while the third phosphine was found to form a C–P bond with dearomatization ...
Agapie, Theodor, Suseno, Sandy
core +1 more source
Photocatalytic regioselective C–H bond functionalizations in arenes
Chemical ScienceThe direct functionalization of C–H bonds has revolutionized the field of synthetic organic chemistry by enabling efficient and atom-economical modification of arenes by avoiding prefunctionalization.
Jun Hu +3 more
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Selectivity Control in the Palladium-catalyzed Cross-coupling of Alkyl Nucleophiles [PDF]
, 2016 Site-selectivity remains a major challenge in metal-catalyzed C–H bond functionalization. Most existing strategies rely on the introduction of a directing group or on the intrinsic reactivity of the substrate.
Baudoin, Olivier
core +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Iridium-Catalyzed Silylation of Unactivated C-H Bonds. [PDF]
, 2019 The functionalization of primary C-H bonds has been a longstanding challenge in catalysis. Our group has developed a series of silylations of primary C-H bonds that occur with site selectivity and diastereoselectivity resulting from an approach to run ...
Hartwig, John F, Romero, Erik A
core
Exploiting double exchange Diels-Alder cycloadditions for immobilization of peptide nucleic acids on gold nanoparticles [PDF]
, 2020 The generation of PNA-decorated gold nanoparticles (AuNPs) has revealed to be more difficult as compared to the generation of DNA-functionalized ones. The less polar nature of this artificial nucleic acid system and the associated tendency of the neutral
Cadoni, Enrico +4 more
core +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Recent advances towards electrophotocatalytic C(sp2 )-H functionalization
SynOpenThe direct functionalization of inert C(sp²)-H bonds represents a central and challenging objective in synthetic chemistry. Photoelectrocatalysis has recently ushered in a transformative paradigm for efficient C(sp²)-H bond functionalization.
Peng Qian, Jiusi Yang
doaj +1 more source