Results 111 to 120 of about 521,522 (308)

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

open access: yesAdvanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu   +10 more
wiley   +1 more source

c-Jun Overexpression Accelerates Wound Healing in Diabetic Rats by Human Umbilical Cord-Derived Mesenchymal Stem Cells

open access: yesStem Cells International, 2020
Objective. Mesenchymal stem cells (MSCs) are considered a promising therapy for wound healing. Here, we explored the role of c-Jun in diabetic wound healing using human umbilical cord-derived MSCs (hUC-MSCs). Methods.
Chun Yue   +5 more
doaj   +1 more source

Inhibiting IL-1 signaling pathways to inhibit catabolic processes in disc degeneration [PDF]

open access: yes, 2016
Intervertebral disc degeneration is characterized by an imbalance between catabolic and anabolic signaling, with an increase in catabolic cytokines particularly IL-1β, a key regulator of IVD degeneration.
Bachmeier   +47 more
core   +1 more source

Interfacial Modulation for High‐Efficiency Large‐Area Organic Photovoltaics and Perovskite‐Organic Tandem Solar Modules

open access: yesAdvanced Functional Materials, EarlyView.
Self‐assembled monolayers (SAMs) are promising hole‐transporting materials for organic photovoltaics (OPVs), but suffer from self‐aggregation and poor large‐area uniformity. We find that interfacial modification using nicotinic hydrazide can eliminate the residual SAM aggregates by forming energetically favorable complexes, yielding uniform SAM.
Seongwon Yoon   +10 more
wiley   +1 more source

Dual-mechanistic regulation of podocyte pyroptosis in lupus nephritis by the AP-1 complex: transcriptional activation of NLRP3 and lactate-mediated ubiquitination inhibition

open access: yesCell Communication and Signaling
Background Lupus nephritis (LN) is driven by podocyte pyroptosis triggered by NLRP3 inflammasome activation, yet the dual regulatory mechanisms—transcriptional control by the AP-1 complex (c-JUN/c-FOS heterodimer) and post-translational modulation via ...
Pei-lei Chen   +17 more
doaj   +1 more source

Synsepalum dulcificum extracts exhibit cytotoxic activity on human colorectal cancer cells and upregulate c-fos and c-jun early apoptotic gene expression

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2018
Objective: To explore cytotoxicity of Synsepalum dulcificum (S. dulcificum) Daniell (Sapotaceae) on human colon cancer (HCT-116 and HT-29), human monocytic leukemia (THP-1) and normal (HDFn) cell lines, and its effect on the expression of early apoptotic
Jichang Seong   +2 more
doaj   +1 more source

The repair Schwann cell and its function in regenerating nerves. [PDF]

open access: yes, 2016
Nerve injury triggers the conversion of myelin and non-myelin (Remak) Schwann cells to a cell phenotype specialised to promote repair. Distal to damage, these repair Schwann cells provide the necessary signals and spatial cues for the survival of injured
Jessen, KR, Mirsky, R
core   +1 more source

Biocompatible but Antibacterial Mechanism of Graphene Oxide for Sustainable Antibiotics

open access: yesAdvanced Functional Materials, EarlyView.
Graphene oxide (GO) exhibits selective antibacterial activity through specific interactions between its oxygen functional groups and bacterial membrane phospholipid POPG, causing membrane destabilization while maintaining biocompatibility. Model membrane studies and infected wound models in mice and pigs demonstrate effective bacterial suppression and ...
Sujin Cha   +15 more
wiley   +1 more source

High Erk-1 activation and Gadd45a expression as prognostic markers in high risk pediatric haemolymphoproliferative diseases [PDF]

open access: yes, 2009
Studies on activated cell-signaling pathways responsible for neoplastic transformation are numerous in solid tumors and in adult leukemias. Despite of positive results in the evolution of pediatric hematopoietic neoplasias, there are some high-risk ...
Velia D'Angelo   +35 more
core   +1 more source

Multi‐Functional ZnO–Te Heterojunction Devices Enabling Compact Frequency Quadrupler

open access: yesAdvanced Functional Materials, EarlyView.
Wafer‐scale ZnO–Te heterojunction devices featuring tunable double negative differential transconductance (D‐NDT) are demonstrated at ≤ 200°C. Leveraging this unique characteristic, a single‐stage frequency quadrupler is realized, achieving a 64%–75% reduction in device count.
Jae Hyeon Jun   +8 more
wiley   +1 more source

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