Results 81 to 90 of about 23,377,083 (210)
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1991 Genetic alterations of the c-myc locus in various malignancies and the ability of c-myc to transform cultured cells and induce tumors in transgenic animals attest to its central role in many neoplasms. By dissecting the c-Myc protein, a number of critical functional domains of c-Myc have been identified and characterized; these findings suggest a model
openaire +2 more sources
Life or cell death: identifying c-Myc regulated genes in two distinct tissues [PDF]
The c-myc oncogene is over-expressed or deregulated in many human cancers. c-myc encodes a transcription factor, the oncoprotein c-Myc (Myc), which acts as a master regulator of genes involved in such diverse cellular processes as replication and growth,
Robson, Samuel Charles
core
, 2016 (A) 293T cells were transfected with HA-RLIM and myc-c-Myc expression vectors and immunoprecipitation was carried out with anti-myc or anti-HA antibodies as indicated. Immunoprecipitates were subjected to WB with anti-HA and anti-myc antibodies. (B) and (
Rui Gao (247606) +4 more
core +1 more source
Cdc45 Is a Critical Effector of Myc-Dependent DNA Replication Stress
Cell Reports, 2013 c-Myc oncogenic activity is thought to be mediated in part by its ability to generate DNA replication stress and subsequent genomic instability when deregulated.
Seetha V. Srinivasan +4 more
doaj +1 more source
, 2011 Copyright information:Taken from "Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis"BMC Biology 2004;2():26-26.Published online 21 Dec 2004PMCID:PMC544575.Copyright ...
Sevasti Zervou (71022) +5 more
core +1 more source
, 2013 (A) Procedure of obtaining of BSA-c-myc conjugate labeled by FITC for flow cytometry detection of targeted anti-c-myc B cells. (i) Conjugation of BSA with FITC using coupling of isothiocyanate with primary amino groups.
Alexander G. Tonevitsky (350317) +14 more
core +1 more source
, 2022 Z-ligustilide (or ligustilide) is found in Angelica sinensis (Oliv.) Diels and may exert potential benefits in cancer treatment. Previous research has reported that ligustilide has anti-cancer effects on several types of cancer cells. However, studies of
Yu-Tang Chen (12409561) +4 more
core +1 more source
RLIM promotes c-Myc ubiquitination.
, 2016 (A) 293T cells were transfected with Flag-Ub, myc-c-Myc, HA-RLIM and HA-RLIMC596A in combinations as indicated. Ectopically expressed c-Myc was immunoprecipitated by anti-myc antibody followed by WB with anti-Flag antibody.
Rui Gao (247606) +4 more
core +1 more source
The role of c-Myc-RBM38 loop in the growth suppression in breast cancer
Journal of Experimental & Clinical Cancer Research, 2017 Background RNA-binding protein 38 (RBM38) is a member of the RNA recognition motif (RRM) family of RNA-binding proteins (RBPs). RBM38 often exerts its function by forming regulatory loops with relevant genes.
Xiao-Xia Li +9 more
doaj +1 more source
Eye phenotypes observed for control (c-mycCtrl) and c-myc-deficient lens (c-mycLe-Cre).
, 2014 Eye phenotypes observed for control (c-mycCtrl) and c-myc-deficient lens (c-mycLe-Cre).
Paulo M. G. Rodrigues (439795) +4 more
core +1 more source