Results 61 to 70 of about 467,569 (310)

In situ Raman study of redox state changes of mitochondrial cytochromes in a perfused rat heart. [PDF]

PLoS ONE, 2013
We developed a Raman spectroscopy-based approach for simultaneous study of redox changes in c-and b-type cytochromes and for a semiquantitative estimation of the amount of oxygenated myoglobin in a perfused rat heart.
Nadezda A Brazhe, Marek Treiman, Barbara Faricelli, Jakob H Vestergaard, Olga Sosnovtseva   +4 more
doaj   +1 more source

Structure of cytochrome a3-Cua3 couple in cytochrome c oxidase as revealed by nitric oxide binding studies [PDF]

, 1979
The addition of NO to oxidized cytochrome c oxidase (ferrocytochrome c:oxygen oxidoreductase, EC 1.9.3.1) causes the appearance of a high-spin heme electron paramagnetic resonance (EPR) signal due to cytochrome a3. This suggests that NO coordinates to Cu{
Bocian, David F., Brudvig, Gary W., Chan, Sunney I., Stevens, Tom H.   +3 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Bromate reduction by Shewanella species depends on both endogenous and exogenous iron

Frontiers in Microbiology
In this study, we isolated Shewanella sp. strain M-Br, a bromate (BrO3−)-reducing bacterium, from seawater. In the presence of lactate as the electron donor, this strain reduced 250 μM bromate to bromide (Br−) in 3 days.
Natsuki Takahashi, Hiroko Fujiya, Haruhiko Sato, Shigeki Yamamura, Seigo Amachi   +4 more
doaj   +1 more source

Widespread Distribution and Functional Specificity of the Copper Importer CcoA: Distinct Cu Uptake Routes for Bacterial Cytochrome c Oxidases

mBio, 2018
Cytochrome c oxidases are members of the heme-copper oxidase superfamily. These enzymes have different subunits, cofactors, and primary electron acceptors, yet they all contain identical heme-copper (CuB) binuclear centers within their catalytic subunits.
Bahia Khalfaoui-Hassani, Hongjiang Wu, Crysten E. Blaby-Haas, Yang Zhang, Federica Sandri, Andreia F. Verissimo, Hans-Georg Koch, Fevzi Daldal   +7 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Structure of Geobacter OmcZ filaments suggests extracellular cytochrome polymers evolved independently multiple times

eLife, 2022
While early genetic and low-resolution structural observations suggested that extracellular conductive filaments on metal-reducing organisms such as Geobacter were composed of type IV pili, it has now been established that bacterial c-type cytochromes ...
Fengbin Wang, Chi Ho Chan, Victor Suciu, Khawla Mustafa, Madeline Ammend, Dong Si, Allon I Hochbaum, Edward H Egelman, Daniel R Bond   +8 more
doaj   +1 more source

An effective long-range attraction between protein molecules in solutions studied by small angle neutron scattering

, 2005
Small angle neutron scattering intensity distributions taken from cytochrome C and lysozyme protein solutions show a rising intensity at very small wave vector, Q, which can be interpreted in terms of the presence of a weak long-range attraction between ...
A. Lawlor, Emiliano Fratini, J. Z. Xia, O. D. Velev, Piero Baglioni, Sow-Hsin Chen, Wei-Ren Chen, Yun Liu   +7 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Molecular Taxonomy of Conogethes punctiferalis and Conogethes pinicolalis (Lepidoptera: Crambidae) Based on Mitochondrial DNA Sequences

Journal of Integrative Agriculture, 2014
Conogethes punctiferalis (Guenée) (Lepidoptera: Crambidae) was originally considered as one species with fruit-feeding type (FFT) and pinaceae-feeding type (PFT), but it has subsequently been divided into two different species of Conogethes punctiferalis
Jing WANG, Tian-tao ZHANG, Zhen-ying WANG, Kang-lai HE, Yong LIU, Jing LI   +5 more
doaj   +1 more source