Results 81 to 90 of about 84,931 (265)
Functional activities of C-reactive protein on neutrophils [PDF]
C-reactive protein (CRP) is a member of the pentraxin family which opsonises S. pneumoniae through its binding to phosphorylcholine. In addition, CRP binds to Fcγ receptors: FcγRI with high affinity and, probably, FcγRIIA with lower affinity.
Rodriguez, Jairo Antonio
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Research progress on biomarkers of traumatic brain injury
Animal Models and Experimental Medicine, EarlyView.Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen +8 more
wiley +1 more source
Regulation of C-Type Lectin Receptor-Mediated Antifungal Immunity [PDF]
Frontiers in Immunology, 2018 Of all the pathogen recognition receptor families, C-type lectin receptor (CLR)-induced intracellular signal cascades are indispensable for the initiation and regulation of antifungal immunity. Ongoing experiments over the last decade have elicited diverse CLR functions and novel regulatory mechanisms of CLR-mediated-signaling pathways. In this review,
Juan Tang +5 more
openaire +3 more sources
Porcine kidney xenotransplantation: From primate models to clinical reality
Animal Models and Experimental Medicine, EarlyView.In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo +3 more
wiley +1 more source
Characterization of the receptors for mycobacterial cord factor in Guinea pig. [PDF]
PLoS ONE, 2014 Guinea pig is a widely used animal for research and development of tuberculosis vaccines, since its pathological disease process is similar to that present in humans.
Kenji Toyonaga +2 more
doaj +1 more source
Sensing of cell death by myeloid C-type lectin receptors [PDF]
Current Opinion in Immunology, 2013 Molecules associated with dead or dying cells can be detected by receptors on macrophages and dendritic cells. Signals from these receptors impact myeloid cell function and play a role in determining whether death is silent or proinflammatory, tolerogenic or immunogenic. Prominent among myeloid receptors detecting dead cells are C-type lectin receptors
David Sancho, Caetano Reis e Sousa
openaire +2 more sources
Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
Toxins, 2019 Snake venoms contain an astounding variety of different proteins. Among them are numerous C-type lectin family members, which are grouped into classical Ca2+- and sugar-binding lectins and the non-sugar-binding snake venom C-type lectin-related proteins (
Johannes A. Eble
doaj +1 more source
Identification and characterization of C-type lectin receptors for respiratory viruses [PDF]
, 2015 © 2015 Dr. Wy Ching NgStudies described in this thesis have characterized interactions between respiratory viruses and different C-type lectin receptors.
Ng, Wy Ching
core
Signalling C-Type lectin receptors, microbial recognition and immunity [PDF]
, 2014 Signalling C-type lectin receptors (CLRs) are crucial in shaping the immune response to fungal pathogens, but comparably little is known about the role of these receptors in bacterial, viral and parasitic infections.
Hoving, J. Claire +4 more
core +1 more source