The diverse roles of C-type lectin-like receptors in immunity [PDF]
Frontiers in Immunology, 2023 Our understanding of the C-type lectin-like receptors (CTLRs) and their functions in immunity have continued to expand from their initial roles in pathogen recognition.
Michal Scur +3 more
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C-Type Lectin-Like Receptors: Head or Tail in Cell Death Immunity [PDF]
Frontiers in Immunology, 2020 C-type lectin-like receptors (CLRs) represent a family of transmembrane pattern recognition receptors, expressed primarily by myeloid cells. They recognize not only pathogen moieties for host defense, but also modified self-antigens such as damage ...
Marion Drouin +3 more
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C-Type Lectin-Like Receptors As Emerging Orchestrators of Sterile Inflammation Represent Potential Therapeutic Targets [PDF]
Frontiers in Immunology, 2018 Over the last decade, C-type lectin-like receptors (CTLRs), expressed mostly by myeloid cells, have gained increasing attention for their role in the fine tuning of both innate and adaptive immunity.
Elise Chiffoleau +3 more
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C-type lectin receptor signaling in schistosomiasis [PDF]
Frontiers in ImmunologySchistosomiasis is a major neglected tropical disease caused by helminth parasites of the genus Schistosoma, affecting over 250 million people worldwide and leading to substantial morbidity primarily driven by egg-induced immunopathology.
Santoshi Chaudhary, Parisa Kalantari
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The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors. [PDF]
PLoS Pathogens, 2019 Invasive candidiasis, mainly caused by Candida albicans, is a serious healthcare problem with high mortality rates, particularly in immunocompromised patients. Innate immune cells express pathogen recognition receptors (PRRs) including C-type lectin-like
Aiysha Thompson +11 more
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Investigation of carbohydrate-based molecules of Theileria parva parasites [PDF]
Frontiers in Veterinary ScienceTheileria parva (Tp), the causative agent of East Coast Fever, poses a major threat to Bos taurus cattle in sub-Saharan Africa. Progress towards a stable, affordable, cross-protective subunit vaccine covering more than one major histocompatibility ...
Jeannine Kolakowski +7 more
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C-type lectin receptors and RIG-I-like receptors: new points on the oncogenomics map
Cancer Management and Research, 2012 Anton G Kutikhin, Arseniy E YuzhalinDepartment of Epidemiology, Kemerovo State Medical Academy, Kemerovo, Russian FederationAbstract: The group of pattern recognition receptors includes families of Toll-like receptors, NOD-like receptors, C-type lectin ...
Yuzhalin AE, Kutikhin AG
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Immunoregulatory Property of C-Type Lectin-Like Receptors in Fibrosing Interstitial Lung Diseases [PDF]
International Journal of Molecular Sciences, 2020 Tatsuya Nagano, Wiwin Is EFFENDI
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Pattern recognition receptor signaling in otitis media: immune crosstalk and pathogenic mechanisms [PDF]
Frontiers in ImmunologyOtitis media (OM) remains a prevalent and multifactorial inflammatory disease of the middle ear, especially in pediatric populations. The immune system, particularly pattern recognition receptors (PRRs), plays a central role in detecting microbial ...
Mingwen Guo +5 more
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C-Type Lectin-Like Receptors of the Dectin-1 Cluster: Ligands and Signaling Pathways [PDF]
International Reviews of Immunology, 2013 Gordon Brown, Janet Willment
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