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The diverse roles of C-type lectin-like receptors in immunity [PDF]

open access: yesFrontiers in Immunology, 2023
Our understanding of the C-type lectin-like receptors (CTLRs) and their functions in immunity have continued to expand from their initial roles in pathogen recognition.
Michal Scur   +3 more
doaj   +6 more sources

C-Type Lectin-Like Receptors: Head or Tail in Cell Death Immunity [PDF]

open access: yesFrontiers in Immunology, 2020
C-type lectin-like receptors (CLRs) represent a family of transmembrane pattern recognition receptors, expressed primarily by myeloid cells. They recognize not only pathogen moieties for host defense, but also modified self-antigens such as damage ...
Marion Drouin   +3 more
doaj   +6 more sources

C-type lectin receptors and RIG-I-like receptors: new points on the oncogenomics map

open access: yesCancer Management and Research, 2012
Anton G Kutikhin, Arseniy E YuzhalinDepartment of Epidemiology, Kemerovo State Medical Academy, Kemerovo, Russian FederationAbstract: The group of pattern recognition receptors includes families of Toll-like receptors, NOD-like receptors, C-type lectin ...
Yuzhalin AE, Kutikhin AG
doaj   +3 more sources

C-Type Lectin-Like Receptors As Emerging Orchestrators of Sterile Inflammation Represent Potential Therapeutic Targets [PDF]

open access: yesFrontiers in Immunology, 2018
Over the last decade, C-type lectin-like receptors (CTLRs), expressed mostly by myeloid cells, have gained increasing attention for their role in the fine tuning of both innate and adaptive immunity.
Elise Chiffoleau   +3 more
doaj   +6 more sources

The Dectin-1 and Dectin-2 clusters: C-type lectin receptors with fundamental roles in immunity

open access: yesEMBO Reports
The ability of myeloid cells to recognize and differentiate endogenous or exogenous ligands rely on the presence of different transmembrane protein receptors.
Mariano Malamud, Gordon D Brown
doaj   +2 more sources

Key thermally dimorphic fungal pathogens: shaping host immunity

open access: yesOpen Biology, 2022
Exposure to fungal pathogens from the environment is inevitable and with the number of at-risk populations increasing, the prevalence of invasive fungal infection is on the rise. An interesting group of fungal organisms known as thermally dimorphic fungi
Maxine A. Höft   +2 more
doaj   +1 more source

Innate Immune Sensing of Viruses and Its Consequences for the Central Nervous System

open access: yesViruses, 2021
Viral infections remain a global public health concern and cause a severe societal and economic burden. At the organismal level, the innate immune system is essential for the detection of viruses and constitutes the first line of defense.
Hina Singh, Jeffrey Koury, Marcus Kaul
doaj   +1 more source

The Role of Lectin Receptors and Their Ligands in Controlling Allergic Inflammation

open access: yesFrontiers in Immunology, 2021
More than fifty c-type lectin receptors (CLR) are known and have been identified so far. Moreover, we know the group of galectins and sialic acid-binding immunoglobulin-type lectins that also belong to the carbohydrate-binding receptors of the immune ...
Karin Peters, Marcus Peters
doaj   +1 more source

Comparative transcriptomics reveals the immune dynamics during the molting cycle of swimming crab Portunus trituberculatus

open access: yesFrontiers in Immunology, 2022
Molting is one of the most important biological processes of crustacean species, and a number of molecular mechanisms facilitate this complex procedure. However, the understanding of the immune mechanisms underlying crustacean molting cycle remains very ...
Meimei Liu   +6 more
doaj   +1 more source

Extensive Phenotype of Human Inflammatory Monocyte-Derived Dendritic Cells

open access: yesCells, 2021
Inflammatory monocyte-derived dendritic cells (Mo-DCs) have been described in several chronic inflammatory disorders, such as rheumatoid arthritis (RA), and are suspected to play a detrimental role by fueling inflammation and skewing adaptive immune ...
Frédéric Coutant   +2 more
doaj   +1 more source

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