Results 31 to 40 of about 28,074,578 (229)
Nkrp1 Family, from Lectins to Protein Interacting Molecules
Molecules, 2015 The C-type lectin-like receptors include the Nkrp1 protein family that regulates the activity of natural killer (NK) cells. Rat Nkrp1a was reported to bind monosaccharide moieties in a Ca2+-dependent manner in preference order of GalNac > GlcNAc > ...
Daniel Rozbeský +5 more
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Signaling C-type lectin receptors in antimycobacterial immunity. [PDF]
, 2017 Introduction The mammalian innate immune system is composed of phagocytes such as macrophages and dendritic cells that serve as the first line of defense against microbial infections. These cells express various pattern recognition receptors (PRRs) that
Mohlopheni J Marakalala +4 more
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The fungal pattern recognition receptor, Dectin-1, and the associated cluster of C-type lectin-like receptors [PDF]
FEMS Microbiology Letters, 2008 The mammalian natural killer gene complex (NKC) contains several families of type II transmembrane C-type lectin-like receptors (CLRs) that are best known for their involvement in the detection of virally infected or transformed cells, through the recognition of endogenous (or self) proteinacious ligands.
Cristal, Huysamen, Gordon D, Brown
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Fucoidan Is a Novel Platelet Agonist for the C-type Lectin-like Receptor 2 (CLEC-2) [PDF]
Journal of Biological Chemistry, 2013 Fucoidan, a sulfated polysaccharide from Fucus vesiculosus, decreases bleeding time and clotting time in hemophilia, possibly through inhibition of tissue factor pathway inhibitor. However, its effect on platelets and the receptor by which fucoidan induces cellular processes has not been elucidated.
Bhanu Kanth, Manne +7 more
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Role And Relevance Of Mast Cells In Fungal Infections
Frontiers in Immunology, 2012 In addition to their detrimental role in allergic diseases, mast cells (MCs) are well known to be important cells of the innate immune system. In the last decade, they have been shown to contribute significantly to optimal host defense against numerous ...
Rohit eSaluja +2 more
doaj +1 more source
Filoviruses: Innate Immunity, Inflammatory Cell Death, and Cytokines
Pathogens, 2022 Filoviruses are a group of single-stranded negative sense RNA viruses. The most well-known filoviruses that affect humans are ebolaviruses and marburgviruses. During infection, they can cause life-threatening symptoms such as inflammation, tissue damage,
Jianlin Lu +2 more
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, 2021 Review on C-type lectin-(like) fold – protein-protein interaction patterns and utilization potential. The xls table shows PDB ids and basic characteristics of PDB structures containing at least one C-type lectin-(like) domain ...
Skalova, T (via Mendeley Data)
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Das Hühner CLEC-2 Homolog [PDF]
, 2012 Das Hühner CLEC-2 Homolog: Ein Thrombozytenrezeptor mit aktivierender Funktion Der Natürliche Killer Gen Komplex (NKC) des Huhnes ist auf dem Chromosom 1 lokalisiert und weist zwei C-typ Lektine auf, von denen das eine als Homolog zu CD69 und das andere
Neulen, Marie-Luise
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Innate immunity to Candida albicans
Japanese Dental Science Review, 2015 Candida albicans is not a pathogen in healthy individuals, but can cause severe systemic candidiasis in immunocompromised patients. C. albicans has various virulence factors and activates the innate immune system. Specifically, C.
Yusuke Kiyoura, Riyoko Tamai
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Scientific Reports, 2022 Abstract Podoplanin (PDPN) is intensely expressed on the podocyte membrane in an evolutionally conserved manner. CLEC-2, the endogenous ligand of PDPN, is highly expressed in platelets and also exists in a soluble form in plasma. Normally, podocytes are sequestered from CLEC-2, but when the glomerular barrier is injured, podocytes gain access ...
Keiko Tanaka +6 more
openaire +3 more sources