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Key thermally dimorphic fungal pathogens: shaping host immunity
Open Biology, 2022 Exposure to fungal pathogens from the environment is inevitable and with the number of at-risk populations increasing, the prevalence of invasive fungal infection is on the rise. An interesting group of fungal organisms known as thermally dimorphic fungi
Maxine A. Höft +2 more
doaj +1 more source
Measurement of soluble C-type lectin-like receptor 2 in human plasma [PDF]
Platelets, 2015 Detection of platelet activation in vivo is useful to identify patients at risk of thrombotic diseases. Platelet factor 4 (PF4) and β-thromboglobulin (β-TG) are used for this purpose; however, they are easily released upon the minimal platelet activation that occurs during sampling.
Fuminori, Kazama +13 more
openaire +4 more sources
Innate Immune Sensing of Viruses and Its Consequences for the Central Nervous System
Viruses, 2021 Viral infections remain a global public health concern and cause a severe societal and economic burden. At the organismal level, the innate immune system is essential for the detection of viruses and constitutes the first line of defense.
Hina Singh, Jeffrey Koury, Marcus Kaul
doaj +1 more source
The Role of Lectin Receptors and Their Ligands in Controlling Allergic Inflammation
Frontiers in Immunology, 2021 More than fifty c-type lectin receptors (CLR) are known and have been identified so far. Moreover, we know the group of galectins and sialic acid-binding immunoglobulin-type lectins that also belong to the carbohydrate-binding receptors of the immune ...
Karin Peters, Marcus Peters
doaj +1 more source
Frontiers in Immunology, 2022 Molting is one of the most important biological processes of crustacean species, and a number of molecular mechanisms facilitate this complex procedure. However, the understanding of the immune mechanisms underlying crustacean molting cycle remains very ...
Meimei Liu +6 more
doaj +1 more source
Platelet C-Type Lectin-Like Receptor 2 Reduces Cholestatic Liver Injury in Mice [PDF]
The American Journal of Pathology, 2020 Cholestatic liver injury leads to liver dysfunction. The available evidence suggests that platelets can either promote or reduce liver injury and fibrosis. This study focused on the functions of the C-type lectin-like receptor 2 (CLEC-2), a new special platelet receptor that binds with podoplanin-activating platelets.
Suguru, Maruyama +15 more
openaire +2 more sources
Signalling C-Type Lectins in Antimicrobial Immunity [PDF]
, 2013 Funding: This work was funded by the Wellcome Trust, Medical Research Council and the University of Aberdeen. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer ...
Brown, Gordon D., Drummond, Rebecca A.
core +12 more sources
Extensive Phenotype of Human Inflammatory Monocyte-Derived Dendritic Cells
Cells, 2021 Inflammatory monocyte-derived dendritic cells (Mo-DCs) have been described in several chronic inflammatory disorders, such as rheumatoid arthritis (RA), and are suspected to play a detrimental role by fueling inflammation and skewing adaptive immune ...
Frédéric Coutant +2 more
doaj +1 more source
Pharmaceutics, 2022 New-generation vaccines, formulated with subunits or nucleic acids, are less immunogenic than classical vaccines formulated with live-attenuated or inactivated pathogens.
Diego A. Díaz-Dinamarca +6 more
doaj +1 more source
Diabetes & Vascular Disease Research, 2020 Background: C-type lectin receptors, including Dectin-2, are pattern recognition receptors on monocytes and macrophages that mainly recognize sugars and sugar-like structures present on fungi.
Kathrin Thiem +17 more
doaj +1 more source