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C-type lectins in immunity: recent developments. [PDF]

open access: yesCurr Opin Immunol, 2015
C-type lectin receptors (CLRs) comprise a large superfamily of proteins, which recognise a diverse range of ligands, and are defined by the presence of at least one C-type lectin-like domain (CTLD). Of particular interest are the single extracellular CTLD-containing receptors of the 'Dectin-1' and 'Dectin-2' clusters, which associate with signalling ...
Dambuza IM, Brown GD.
europepmc   +4 more sources

C-type lectin receptors in skin immunity: Emerging new role for CLEC12B

open access: yesAdvances in Biomedical and Health Sciences, 2022
C-type lectin receptors (CLRs) are a superfamily of transmembrane proteins, which consist of one or several C-type lectin-like domains and intracellular signaling motifs, such as immunoreceptor tyrosine-based activation motif (ITAM) or immunoreceptor ...
Lauriane Blot   +2 more
doaj   +1 more source

Role of Lectin in the Response of Aedes aegypti Against Bt Toxin

open access: yesFrontiers in Immunology, 2022
Aedes aegypti is one of the world’s most dangerous mosquitoes, and a vector of diseases such as dengue fever, chikungunya virus, yellow fever, and Zika virus disease.
Intikhab Alam   +11 more
doaj   +1 more source

Integrative analysis workflow for the structural and functional classification of C-type lectins

open access: yesBMC Bioinformatics, 2011
Background It is important to understand the roles of C-type lectins in the immune system due to their ubiquity and diverse range of functions in animal cells.
Koh Geoffrey   +8 more
doaj   +1 more source

The Roles of Direct Recognition by Animal Lectins in Antiviral Immunity and Viral Pathogenesis

open access: yesMolecules, 2015
Lectins are a group of proteins with carbohydrate recognition activity. Lectins are categorized into many families based on their different cellular locations as well as their specificities for a variety of carbohydrate structures due to the features of ...
Yang Liu   +5 more
doaj   +1 more source

Partial Characterization of Lectins Purified from the Surco and Vara (Furrow and Rod) Varieties of Black Phaseolus vulgaris

open access: yesMolecules, 2022
As they manifest specifically and reversibly, lectins are proteins or glycoproteins with the characteristic of agglutinating erythrocytes. Given that grain legume lectins can represent 10% of protein content and can have various biological functions ...
Carmen Valadez-Vega   +3 more
doaj   +1 more source

High Bacterial Agglutination Activity in a Single-CRD C-Type Lectin from Spodoptera exigua (Lepidoptera: Noctuidae)

open access: yesBiosensors, 2017
Lectins are carbohydrate-interacting proteins that play a pivotal role in multiple physiological and developmental aspects of all organisms. They can specifically interact with different bacterial and viral pathogens through carbohydrate-recognition ...
Leila Gasmi   +2 more
doaj   +1 more source

Transgenic Expression of Human C-Type Lectin Protein CLEC18A Reduces Dengue Virus Type 2 Infectivity in Aedes aegypti

open access: yesFrontiers in Immunology, 2021
The C-type lectins, one family of lectins featuring carbohydrate binding domains which participate in a variety of bioprocesses in both humans and mosquitoes, including immune response, are known to target DENV.
Lie Cheng   +18 more
doaj   +1 more source

Drosophila C-type lectins enhance cellular encapsulation [PDF]

open access: yesMolecular Immunology, 2007
C-type lectins are calcium-dependent carbohydrate binding proteins, and animal C-type lectins participate in innate immunity and cell-cell interactions. In the fruit fly Drosophila melanogaster, more than 30 genes encode C-type lectin domains. However, functions of Drosophila C-type lectins in innate immunity are not well understood.
Jingqun, Ao, Erjun, Ling, Xiao-Qiang, Yu
openaire   +2 more sources

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