Results 131 to 140 of about 133,009 (166)

C. elegans select

Nature Methods, 2010
The technical toolkit for Caenorhabditis elegans expands to include experimental selection using antibiotic resistance genes.
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Dopamine receptors in C. elegans

European Journal of Pharmacology, 2004
Dopamine regulates various physiological functions in the central nervous system and the periphery. Dysfunction of the dopamine system is implicated in a wide variety of disorders and behaviors including schizophrenia, addiction, and attention-deficit hyperactivity disorder.
Satoshi, Suo, Shoichi, Ishiura, Hubert H M, Van Tol   +2 more
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Evolution of lifespan in C. elegans

Nature, 2000
It was proposed almost 50 years ago that ageing is non-adaptive and is the consequence of a decline in the force of natural selection with age1. This led to the theory that ageing results from detrimental effects late in life of genes that act beneficially in early life1,2, so any genetic alteration that increases lifespan might be expected to reduce ...
D W, Walker, G, McColl, N L, Jenkins, J, Harris, G J, Lithgow   +4 more
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C. elegans Embryonic Morphogenesis

2016
Morphogenesis is a four-dimensional process which involves the crucial interplay between signaling, mechanical forces, and spatial changes. Caenorhabditis elegans presents a simple yet versatile model to study morphogenesis. Here, we review recent progress on cellular and molecular drivers of morphological changes during C.
Vuong-Brender, Thanh T. K., Yang, Xinyi, Labouesse, Michel   +2 more
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Patterning in the C. elegans embryo

Trends in Genetics, 1994
Recent studies reveal preliminary insights into the mechanisms of embryonic patterning in Caenorhabditis elegans. It appears that both embryonic axes and early blastomere fates are determined by a combination of segregating determinants and cell interactions, under the control of maternally expressed genes.
W B, Wood, L G, Edgar
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Axon degeneration in c. elegans

2018
Axons degenerate following injury and during "dying-back" neurodegenerative diseases, which are characterized by early degeneration of synapses and axons. While injury and disease are clearly distinct events, they share some common regulators. Although these problems have been extensively studied, very little is known about which molecules initiate and
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Genome Editing of C. elegans

2017
Caenorhabditis elegans, a 1 mm long free-living nematode, is a traditional model animal for genetic investigations of various biological processes. Characteristic features that make C. elegans a powerful model of choice for eukaryotic genetic studies include its rapid life cycle, well-annotated genome, simple morphology, and transparency.
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[C. elegans defence mechanisms].

Medecine sciences : M/S, 2009
The nematode Caenorhabditis elegans has evolved as a powerful invertebrate model to study innate immunity to pathogens. C. elegans possesses inducible defence mechanisms to protect itself from pathogenic attack, mainly by the production of antimicrobial effector molecules.
Ziegler, Katja, Pujol, Nathalie
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C. elegans

2022
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Xenobiotic metabolism and transport in Caenorhabditis elegans

Journal of Toxicology and Environmental Health - Part B: Critical Reviews, 2021
Jessica H Hartman, Christina M Bergemann, Maxwell C K Leung   +2 more
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