SUSTAINED REAL-WORLD ATTACK REDUCTIONS FOLLOWING BEROTRALSTAT INITIATION AMONG PATIENTS WITH HEREDITARY ANGIOEDEMA WITHOUT C1-INHIBITOR DEFICIENCY [PDF]
Mark Davis‐Lorton +7 more
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Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
Advanced Science, EarlyView.SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao +11 more
wiley +1 more source
In Vivo Biosynthesis of Endogenous and of Human C1 Inhibitor in Transgenic Mice: Tissue Distribution and Colocalization of Their Expression [PDF]
, 2002 G Vinci +7 more
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Anisotropically Wettable Porous Transport Layers for Gas Management in Water Electrolyzers
Advanced Science, EarlyView.Synergistic wetting, achieved by integrating hydrophilic and hydrophobic domains, enhances mass transport in porous transport layers. In situ visualization reveals that dual‐phase wetting suppresses gas accumulation and promotes continuous bubble release, enabling stable, bubble‐free electrolysis within membrane electrode assemblies.
Yunseok Kang +8 more
wiley +1 more source
Revista Cubana de Hematología, Inmunología y HemoterapiaEl angioedema hereditario es una enfermedad poco frecuente, con herencia autosómica dominante que se caracteriza por presentar edemas en piel y en la mucosa de diferentes órganos, fundamentalmente el tubo digestivo y el aparato respiratorio.
Catalino R Ustariz García
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İki Herediter Anjioödem Olgusunda Başarılı Gebelik ve Doğum: Olgu Sunumu
Genel Tıp Dergisi, 2016 Herediter anjioödem C1 inhibitor eksikliği veya disfonksiyonuna bağlı cilt ve mukoza ödemi ile karakterizedir. Herediter anjioödem hastalığının küratif tedavisi yoktur. Hamilelik boyunca hastalığın atak sıklığı artar.
Ahmet Zafer Çalışkaner +2 more
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Advanced Science, EarlyView.Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu +17 more
wiley +1 more source
Advanced Science, EarlyView.Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen +8 more
wiley +1 more source
Efficacy of Lanadelumab in Hereditary Angioedema Patients Switching From C1 Inhibitor Long-Term Prophylaxis: Interim Results From the HELP Open-Label Extension Study [PDF]
, 2019 Marc A. Riedl +9 more
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Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report [PDF]
, 2021 Noémi‐Anna Bara, Valentin Nădășan
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