Results 11 to 20 of about 3,095,271 (376)

Clinical features of genetically characterized types of hereditary angioedema with normal C1 inhibitor: a systematic review of qualitative evidence [PDF]

Orphanet Journal of Rare Diseases, 2020
Background Hereditary angioedema (HAE) with normal C1 inhibitor (C1-INH) (HAEnCI) is associated with skin swellings, abdominal attacks, and the risk of asphyxia due to upper airway obstruction. Several different gene mutations linked to the HAE phenotype
K. Bork, T. Machnig, K. Wulff, Guenther Witzke, S. Prusty, J. Hardt   +5 more
semanticscholar   +2 more sources

SERPING1 mutation update: Mutation spectrum and C1 Inhibitor phenotypes [PDF]

Human Mutation, 2019
C1 inhibitor (C1Inh) deficiency is responsible for hereditary angioedema (C1‐INH‐HAE) and caused by variants of the SERPING1/C1INH/C1NH gene. C1Inh is the major control of kallikrein–kinin system.
D. Ponard, C. Gaboriaud, D. Charignon, A. Ghannam, I. Wagenaar-Bos, D. Roem, A. López-Lera, M. López-Trascasa, M. Tosi, C. Drouet   +9 more
semanticscholar   +2 more sources

Interplay between C1-inhibitor and group IIA secreted phospholipase A₂ impairs their respective function. [PDF]

Immunol Res, 2023
Ferrara AL, Bova M, Petraroli A, Marasco D, Payré C, Fortuna S, Palestra F, Ciardi R, Marone G, Spadaro G, Lambeau G, Loffredo S.   +11 more
europepmc   +2 more sources

Hereditary angioedema with normal C1 inhibitor and factor XII mutation: a series of 57 patients from the French National Center of Reference for Angioedema [PDF]

Clinical and Experimental Immunology, 2016
A. Deroux, I. Boccon-Gibod, O. Fain, P. Pralong, Yann Ollivier, A. Pagnier, K. Djenouhat, A. Du-Thanh, A. Gompel, C. Faisant, David Launay, L. Bouillet   +11 more
semanticscholar   +2 more sources

Retrospective Evaluation of Patients with Angioedema Treated with C1 Inhibitors in an Emergency Department

Eurasian Journal of Emergency Medicine, 2022
Aim:We aimed first to investigate patients who received C1 inhibitor therapy in the emergency department (ED). The patients’ complaints, examination findings, length of stay in the ED and whether the patients were treated with anything other than C1 ...
Sercan Yalçınlı, Selahattin Kıyan, Funda Karbek Akarca   +2 more
doaj   +1 more source

Berotralstat for hereditary angioedema with C1 inhibitor deficiency: a practical guide for clinicians. [PDF]

Front Immunol
Adatia A, Magerl M.
europepmc   +3 more sources

Psychological processes in the experience of hereditary angioedema in adult patients: an observational study

Orphanet Journal of Rare Diseases, 2021
Background Hereditary angioedema associated to C1 inhibitor deficiency (C1-INH-HAE) is a pathological condition characterized by episodes of subcutaneous swelling and it is frequently associated with discomfort and social impairment of the patients, due ...
Livia Savarese, Maria Bova, Assunta Maiello, Angelica Petraroli, Ilaria Mormile, Mauro Cancian, Riccardo Senter, Andrea Zanichelli, Giuseppe Spadaro, Maria Francesca Freda   +9 more
doaj   +1 more source

Utility of Biomarkers for Postpartum Hemorrhage Transfusion Requirements Relating to Amniotic Fluid Embolism

Clinical and Experimental Obstetrics & Gynecology, 2023
Background: We aimed to evaluate the utility of C1 esterase inhibitor, squamous cell carcinoma antigen, and complements C3 and C4 in the prediction of fresh frozen plasma transfusion requirements in postpartum hemorrhage and characterize the involvement ...
Ryuichi Shimaoka, Tomomi Shiga, Ken-Ichirou Morishige   +2 more
doaj   +1 more source

Patterns of C1-Inhibitor/Plasma Serine Protease Complexes in Healthy Humans and in Hereditary Angioedema Patients

Frontiers in Immunology, 2020
C1-inhibitor (C1-INH) is an important regulator of the complement, coagulation, fibrinolytic and contact systems. The quantity of protease/C1-INH complexes in the blood is proportional to the level of the in vivo activation of these four cascade-like ...
E. Kajdácsi, Zsófia Jandrasics, N. Veszeli, Veronika Makó, A. Koncz, Dominik Gulyás, Kinga Viktória Köhalmi, G. Temesszentandrási, L. Cervenak, P. Gál, J. Dobó, S. de Maat, C. Maas, H. Farkas, L. Varga   +14 more
semanticscholar   +1 more source

C1 inhibitor deficiency: 2014 United Kingdom consensus document [PDF]

, 2015
C1 inhibitor deficiency is a rare disorder manifesting with recurrent attacks of disabling and potentially life-threatening angioedema. Here we present an updated 2014 United Kingdom consensus document for the management of C1 inhibitor-deficient ...
Ashworth, F, Bethune, C, Cale, C, Dempster, J, Edgar, D, Gompels, M, Jolles, S, Longhurst, H J, Price, A, Seneviratne, S, Symons, C, Tarzi, M D   +11 more
core   +3 more sources