Results 11 to 20 of about 117,459 (333)

Edema of the Scrotum and Penile Shaft: An Uncommon Initial Presentation of Acquired Angioedema With Low C1-Inhibitor [PDF]

Case Reports in Urology
Acquired angioedema with low C1-inhibitor (AAE-C1-INH) is a rare disorder characterized by an acquired deficiency in the C1 esterase inhibitor (C1-INH). This case report describes a 79-year-old patient presenting to the emergency department for painless ...
Meghan V. Matheny, Timothy Craig, Joseph Y. Clark   +2 more
doaj   +2 more sources

C1-inhibitor to prevent intracerebral hemorrhage-related secondary brain injury [PDF]

Fluids and Barriers of the CNS
Background Preclinical studies indicate that the systemic application of C1-inhibitor, clinically used to treat hereditary angioedema, reduces secondary brain injury after ischemic stroke. This study assessed the effect of C1-inhibitor on secondary brain
Kevin Akeret, Bart R. Thomson, Subhajit Ghosh, Marc Nolte, Urs Fischer, Rok Humar, Luca Regli, Dominik J. Schaer, Michael Hugelshofer, Raphael M. Buzzi   +9 more
doaj   +2 more sources

Psychological processes in the experience of hereditary angioedema in adult patients: an observational study

Orphanet Journal of Rare Diseases, 2021
Background Hereditary angioedema associated to C1 inhibitor deficiency (C1-INH-HAE) is a pathological condition characterized by episodes of subcutaneous swelling and it is frequently associated with discomfort and social impairment of the patients, due ...
Livia Savarese, Maria Bova, Assunta Maiello, Angelica Petraroli, Ilaria Mormile, Mauro Cancian, Riccardo Senter, Andrea Zanichelli, Giuseppe Spadaro, Maria Francesca Freda   +9 more
doaj   +1 more source

Utility of Biomarkers for Postpartum Hemorrhage Transfusion Requirements Relating to Amniotic Fluid Embolism

Clinical and Experimental Obstetrics & Gynecology, 2023
Background: We aimed to evaluate the utility of C1 esterase inhibitor, squamous cell carcinoma antigen, and complements C3 and C4 in the prediction of fresh frozen plasma transfusion requirements in postpartum hemorrhage and characterize the involvement ...
Ryuichi Shimaoka, Tomomi Shiga, Ken-Ichirou Morishige   +2 more
doaj   +1 more source

C1 inhibitor deficiency: 2014 United Kingdom consensus document [PDF]

, 2015
C1 inhibitor deficiency is a rare disorder manifesting with recurrent attacks of disabling and potentially life-threatening angioedema. Here we present an updated 2014 United Kingdom consensus document for the management of C1 inhibitor-deficient ...
Ashworth, F, Bethune, C, Cale, C, Dempster, J, Edgar, D, Gompels, M, Jolles, S, Longhurst, H J, Price, A, Seneviratne, S, Symons, C, Tarzi, M D   +11 more
core   +3 more sources

Quantification of C1 esterase inhibitor in human serum by enzyme-linked immunosorbent assay: Correlation with turbidimetric immunoassay

Медицинская иммунология, 2023
C1 inhibitor of serine proteases (C1-INH) performs a regulatory function in the complement system and vascular permeability. Deficiency of C1-INH leads to various forms of angioedema, including hereditary angioedema (HAE).
N. P. Gorbunov, A. V. Zhakhov, I. N. Gorbunova, A. M. Milichkina, I. V. Drozd, A. V. Gubanova, E. M. Danilova, R. N. Kuznecova, T. V. Savin, A. G. Burtseva, N. V. Pigareva, A. M. Ischenko, Areg A. Totolian   +12 more
doaj   +1 more source

Hereditary angioedema (HAE) in children and adolescents : a consensus on therapeutic strategies [PDF]

, 2012
Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with intermittent episodes of potentially life-threatening angioedema ...
Aberer, Werner, Eberl, Wolfgang, Faßhauer, Maria, Kreuz , Wolfhart, Kurnik, Karin, Kühne, Thomas, Magerl, Markus, Martinez Saguer, Inmaculada, Meyer-Olson, Dirk, Späth, Peter J., Staubach-Renz, Petra, Wahn, Volker   +11 more
core   +1 more source

New treatments addressing the pathophysiology of hereditary angioedema

Clinical and Molecular Allergy, 2008
Hereditary angioedema is a serious medical condition caused by a deficiency of C1-inhibitor. The condition is the result of a defect in the gene controlling the synthesis of C1-inhibitor, which regulates the activity of a number of plasma cascade systems.
Davis Alvin E
doaj   +1 more source

Study on separation and purification process of C1 esterase inhibitor

Zhongguo shuxue zazhi, 2022
Objective To study the technology of separating and purifying C1 esterase inhibitor (C1-INH) by using the waste washing liquid as raw materia during the preparation of human prothrombin complex (PCC) l.
Jiabin XU, Yawen LI, Jiali GONG, Erhua LUO, Meng ZHANG   +4 more
doaj   +1 more source

Activation of coagulation factor XI, without detectable contact activation in dengue haemorrhagic fever [PDF]

, 2001
A prospective cohort study was performed in 50 patients with dengue haemorrhagic fever (DHF) to determine the potential role of the contact activation system and factor XI activation (intrinsic pathway) in the coagulation disorders in DHF.
Bajzar, Bhamarapravati, Broze, Broze, Broze, Broze, Chetaille, Davie, Gailani, Groen, Jansen, Levi, Meijers, Minnema, Minnema, Minnema, Mosnier, Naito, Perez-Rigau, Pixley, Srichaikul, Ten Cate, Van der Poll, Van Gorp, Van Gorp, Von dem Borne, Von dem Borne, Wang, World Health Organization., Wuillemin   +29 more
core   +2 more sources