Results 71 to 80 of about 117,459 (333)

The international WAO/EAACI guideline for the management of hereditary angioedema – the 2017 revision and update [PDF]

, 2018
Hereditary Angioedema (HAE) is a rare and disabling disease. Early diagnosis and appropriate therapy are essential. This update and revision of the global guideline for HAE provides up-to-date consensus recommendations for the management of HAE.
Aabom, Abdel-Karim, Agostoni, Alexander Nast, Anete S. Grumach, Antonio, Aygoren-Pursun, Aygoren-Pursun, Banerji, Banerji, Banta, Bas, Bas, Berkel, Bernstein, Bernstein, Bernstein, Bernstein, Betschel, Binkley, Black, Blackmore, Blohme, Boccon-Gibod, Bonnekoh, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bouillet, Bouillet, Bouillet, Bouillet, Bowen, Bowen, Bowen, Bowen, Boyle, Brackertz, Brozek, Brozek, Bruce Ritchie, Bruce Zuraw, Brunskill, Bygum, Bygum, Caballero, Caballero, Caballero, Caballero, Caballero, Caballero, Caldwell, Caliskaner, Christiansen, Cicardi, Cicardi, Cicardi, Cicardi, Cicardi, Cicardi, Constance Katelaris, Craig, Craig, Craig, Craig, Craig, Craig, Craig, Cronin, Crowther, Czaller, de Maat, de Rojas Hernandez Fernandez, De Serres, Dewald, Dinkelacker, Donaldson, Donaldson, Donaldson, Dumitru Moldovan, Emel Aygören-Pürsün, Erikson, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farrell, Fernando, Fields, Forrest, Fox, Frank, Frank, Fust, Galan, Germenis, Gilad, Gobert, Gompels, Gonzalez-Quevedo, Gorman, Greve, Grumach, Guyatt, Halbmayer, Hedner, Henriette Farkas, Henrik Balle Boysen, Hilary Longhurst, Hochberg, Hofstra, Ignacio Ansotegui, Inmaculada Martinez-Saguer, Jacques, Jurado-Palomo, Kalaria, Kaplan, Kaplan, Kaplan, Karim, Kohalmi, Konrad Bork, Kreuz, Kunschak, Lang, Lanny Rosenwasser, Levy, Li, Longhurst, Longhurst, Longhurst, Lopez-Lera, Lumry, Lumry, Lumry, Magerl, Magerl, Magerl, Marc Riedl, Marcus Maurer, Mario Sánchez-Borges, Markus Magerl, Martinez-Saguer, Martinez-Saguer, Martinez-Saguer, Martinez-Saguer, Martinez-Saguer, Maurer, Maurer, Maurer, Michihiro Hide, Moldovan, Moldovan, Muhlberg, Nanda, Nasr, Nathani, Nielsen, Nussberger, Ogston, Pappalardo, Pappalardo, Paul Potter, Pedrosa, Peveling-Oberhag, Rahal, Rasmussen, Reshef, Richard Lockey, Riedl, Riedl, Riedl, Riedl, Rocha, Rosen, Rosen, Ruby Pawankar, Saule, Schreiber, Schulz, Sheffer, Sheffer, Spath, Speletas, Staubach, Stephen Betschel, Tarzi, Terpstra, Thoufeeq, Timothy Craig, Toh, Tom Bowen, Tourangeau, Tuong, van Doorn, van Veen, Visy, Waytes, Weiler, Wentz, Whalley, Whalley, William R. Lumry, Wilson, Wu, Yuxiang Zhi, Zanichelli, Zanichelli, Zanichelli, Zilberberg, Zotter, Zotter, Zotter, Zuberbier, Zuraw, Zuraw, Zuraw, Zuraw, Zuraw, Zuraw, Ärzteschaft   +238 more
core   +2 more sources

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Classification, diagnosis, and approach to treatment for angioedema: Consensus report from the Hereditary Angioedema International Working Group [PDF]

, 2014
Angioedema is defined as localized and self-limiting edema of the subcutaneous and submucosal tissue, due to a temporary increase in vascular permeability caused by the release of vasoactive mediator(s). When angioedema recurs without significant wheals,
Adam, Agostoni, Agostoni, Agostoni, Alsenz, Alsenz, Bafunno, Bas, Beltrami, Benson, Bentsianov, Binkley, Blais, Blanch, Blohme, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bork, Bouillet-Claveyrolas, Bowen, Bowen, Branellec, Brasher, Brecy, Bright, Brown, Brown, Burkhart, Bygum, Bygum, Byrd, Byrd, Caballero, Caldwell, Campo, Castelli, Cicardi, Cicardi, Cicardi, Cicardi, Cicardi, Cicardi, Cicardi, Cicardi, Cichon, Cocchio, Colas, Corso, Corte, Craig, Craig, Cugno, Cugno, Cugno, Cugno, Cupido, D'Incan, Dean, Dewald, Dobbels, Donaldson, Donaldson, Donaldson, Du-Thanh, Duan, Farkas, Farkas, Fields, Frank, Gelee, Gelfand, Gompels, Grant, Hassan, Hauptmann, Hauptmann, He, Jackson, Jackson, Jackson, Kalmar, Kalmar, Kaplan, Kiss, Kostis, Kostis, Lam, Levi, Lin, Longhurst, Longhurst, Lopez-Lera, Lopez-Lera, Lumry, Makani, Mandle, Marcos, Martin, Martinez-Saguer, Messerli, Miller, Molinaro, Montinaro, Nielsen, Nussberger, Nussberger, Osler, Pappalardo, Pappalardo, Patel, Pellacani, Quinke, Roche, Roche, Rosen, Rye Rasmussen, Sanchez-Borges, Sanchez-Cano, Sands, Schreiber, Slater, Steinbach, Stray-Pedersen, Tarzi, Tedeschi, Thelwel, Toh, Tosi, Vitrat-Hincky, Wagenaar-Bos, Waytes, Weller, Wilson, Zanichelli, Zanichelli, Ziakas, Zingale, Zingale, Zuberbier, Zuraw, Zuraw, Zuraw, Zuraw, Zuraw   +151 more
core   +1 more source

Upregulation of C1-inhibitor in pancreatic cancer [PDF]

Oncotarget, 2019
The complement system has recently sparked more interest in cancer research. The classical pathway is initiated by activation of the C1 complex, which irreversibly can be bound to and inhibited by C1-INH. We have previously shown that C1-INH is upregulated in human glioblastoma (astrocytoma grade IV) on both gene and protein level.
Emma Liljedahl, Emma Liljedahl, Henrietta Nittby Redebrandt, Henrietta Nittby Redebrandt, Leif G. Salford, Leif G. Salford, Karolina Förnvik, Karolina Förnvik, Kurt Osther   +8 more
openaire   +3 more sources

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Proteomic analysis of skin invasion by blood fluke larvae. [PDF]

, 2008
BackgroundDuring invasion of human skin by schistosome blood fluke larvae (cercariae), a multicellular organism breaches the epidermis, basement membrane, and dermal barriers of skin.
Braschi, Simon, Debnath, Moumita, Hansell, Elizabeth, Ingram, Jessica, Lim, KC, McKerrow, James H, Medzihradszky, Katalin F, Sajid, Mohammed   +7 more
core   +1 more source

Translating a Preclinically Tested 15 Hz rTMS Protocol to Humans With Chronic Spinal Cord Injury: A Safety and Feasibility Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Repetitive transcranial magnetic stimulation (rTMS) is a non‐invasive brain stimulation strategy with a demonstrated potential to reinforce the residual pathways after a spinal cord injury (SCI). A preclinically tested high‐frequency (15 Hz) rTMS (15 Hz rTMS) protocol was shown to induce corticospinal tract axon regeneration growth ...
Nabila Brihmat, Mehmed B. Bayram, Morgan Paine, Janelle Carnahan, Jian Zhong, Xiaofei Guan, Guang H. Yue, Soha Saleh, Gail F. Forrest   +8 more
wiley   +1 more source

C1-inhibitor protects against brain ischemia–reperfusion injury via inhibition of cell recruitment and inflammation

Neurobiology of Disease, 2005
Previous studies demonstrated that C1-inhibitor (C1-INH), a complement and contact-kinin systems inhibitor, is neuroprotective in cerebral ischemia.
Claudio Storini, Emanuela Rossi, Veronica Marrella, Maria Distaso, Robert Veerhuis, Carlo Vergani, Luigi Bergamaschini, Maria-Grazia De Simoni   +7 more
doaj   +1 more source

Microstructural Evolution and Mechanical Property Degradation of Sn0.5Ag0.7Cu5Bi Solder Joints with High Indium Alloying

Advanced Engineering Materials, EarlyView.
This study identifies 12 wt% indium (In) as the optimal composition for Sn0.5Ag0.7Cu5Bi solder joints, achieving 87% ductile fracture and 81% suppression of intermetallic compound (IMC) growth versus 4 wt% In. High‐In alloys (15–17 wt%) show abnormal IMC thickening due to thermal activation.
Liuwei Wang, Huidong Gu, Xiaojing Wang, Shanshan Cai, Saad Alshammari, Gaber A. M. Mersal, Yanlai Wang, Xulei Wu, Hanhui Lei, Juanna Ren, Mohamed M. Ibrahim, Terence X. Liu   +11 more
wiley   +1 more source