Presence of C1-inhibitor polymers in a subset of patients suffering from hereditary angioedema. [PDF]
PLoS ONE, 2014 Hereditary angioedema (HAE) is a potentially life-threatening disease caused by mutations in the gene encoding the serine protease inhibitor (serpin) C1 inhibitor (C1-inh).
Daniel Elenius Madsen +5 more
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Immunity, Inflammation and Disease, 2017 The clinical characteristics and icatibant‐treatment outcomes of patients with hereditary angioedema with normal C1 inhibitor (HAE‐nC1 INH) are limited.
L. Bouillet +6 more
semanticscholar +1 more source
Enzimreakciók vizsgálata a moduláris szerveződés, az atomi kölcsönhatás és a kvantummechanika szintjein. A fehérje biofizika tudományos iskolája = Insight into the Enzyme Action at Levels of modular Organization, Atomic Interactions and Quantum-Mechanics. School of Protein Biophysics [PDF]
, 2009 Az elmúlt 3 év koherens kutató munkája során születtek speciális tudományos eredmények és levontunk ezekből általános következtetéseket is. Munkánk mérlege a nemzetközi folyóiratokban megjelent 30 közlemény összesen 130 IF-al. Molekuláris immunológiai
Barna, László +18 more
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Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
C1 Inhibitor Deficiency and Angioedema of the Small Intestine Masquerading as Crohn’s Disease
Canadian Journal of Gastroenterology, 2000 A case of C1 inhibitor deficiency presenting as localized edema of the small intestine is described. A 16-year-old, previously healthy woman presented with recurrent attacks of abdominal pain and vomiting following minor abdominal trauma.
Kelly W Burak, Gary R May
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P60: INTRODUCTION OF BERINERT® SC (HUMAN C1‐ESTERASE INHIBITOR) ADMINISTRATION IN THE HOME SETTING TO SUPPORT PROPHYLACTIC TREATMENT OF HEREDITARY ANGIOEDEMA PATIENTS [PDF]
, 2021 openalex +1 more source
Guideline: Hereditary angioedema due to C1 inhibitor deficiency
Allergo Journal International, 2019 S1Guideline of the German Society for Angioedema (Deutsche Gesellschaft für Angioödeme, DGA), German Society for Internal Medicine (Deutsche Gesellschaft für Innere Medizin, DGIM), German Society for Otorhinolaryngology (Deutsche Gesellschaft für Hals ...
K. Bork +12 more
semanticscholar +1 more source
Glycosaminoglycans affect the interaction of human plasma kallikrein with plasminogen, factor XII and inhibitors [PDF]
, 2003 Human plasma kallikrein, a serine proteinase, plays a key role in intrinsic blood clotting, in the kallikrein-kinin system, and in fibrinolysis. The proteolytic enzymes involved in these processes are usually controlled by specific inhibitors and may be ...
Araujo, Mariana da Silva +7 more
core +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Treatment of hereditary angioedema with plasma-derived C1 inhibitor
Therapeutics and Clinical Risk Management, 2008 Michael J Prematta, Tracy Prematta, Timothy J CraigSection of Allergy and Immunology, Penn State University, Milton S. Hershey Medical Center, PA, USABackground: Plasma-derived C1 inhibitor (C1-INH) concentrate is a treatment option for acute hereditary ...
Michael J Prematta +2 more
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