Results 181 to 190 of about 61,741 (331)

Psychometric study of the SF-36v2 in hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE). [PDF]

Orphanet J Rare Dis, 2022
Palao-Ocharan P, Prior N, Pérez-Fernández E, Caminoa M, DV-HAE-QoL Study Group, Caballero T.   +5 more
europepmc   +1 more source

Plasma levels of neutrophil elastase-Alpha1-proteinase inhibitor complexes and factor XIII (including subunits A and S) in septicemia and leucemia [PDF]

, 1983
Duswald, Karl-Heimo, Egbring, R., Fritz, Hans, Hiller, E., Jochum, Marianne, Klingemann, H. - G.   +5 more
core   +1 more source

Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics

American Journal of Hematology, EarlyView.
ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan, Yang Liu, Heng‐Huan Lee, Wei Wang, Joseph McIntosh, Yijing Li, Jovanny Vargas, Yue Fei, Sairah Ahmed, Lukas M. Simon, Michael Wang   +10 more
wiley   +1 more source

Pathways of Neutrophil Granulocyte Activation in Hereditary Angioedema with C1 Inhibitor Deficiency. [PDF]

Clin Rev Allergy Immunol, 2021
Kajdácsi E, Veszeli N, Mező B, Jandrasics Z, Kőhalmi KV, Ferrara AL, Cervenak L, Varga L, Farkas H.   +8 more
europepmc   +1 more source

Life expectancy in Italian patients with hereditary angioedema due to C1-inhibitor deficiency [PDF]

, 2020
Francesca Perego, Antonio Gidaro, Andrea Zanichelli, Mauro Cancian, Francesco Arcoleo, Riccardo Senter, Maria Bova, Tiziana De Pasquale, Maria Domenica Guarino, Mariangela Lo Pizzo, Chiara Frigerio, Piergiorgio Duca, Marco Cicardi   +12 more
openalex   +1 more source

Safety and Effectiveness of Sutimlimab in Cold Agglutinin Disease: A Real‐World International Experience

American Journal of Hematology, EarlyView.
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo, Elisa Sambruna, Yoshitaka Miyakawa, Marc Michel, Carlo Visco, Michael Fillitz, George Kannourakis, Maria Bruna Greve, Moritz Kleemiss, Johan Cid, Andrea Patriarca, Laura Pavan, Arbana Dizdari, Nilla Maschio, Antonella Sau, Cinzia Bitetti, Riccardo Mario Colombo, Luigi Curreli, Dorela Lame, Uros Markovic, Fabrizio Pappagallo, Giacinto Luca Pedone, Davide Rapezzi, Vincenzo Sammartano, Nicola Tumedei, Antonio Giovanni Solimando, Jalink Marit, Luana Fianchi, Jahanzaib Khwaja, Antonio De Vivo, Francesco Lanza, Fabrizio Vianello, Esther N. Oliva, Catherine Broome, Francesco Passamonti, Ulrich Jaeger, Bernd Jilma, Guillaume Moulis, Wilma Barcellini   +38 more
wiley   +1 more source

Long‐Term Follow Up of Two Patients With Variants in the Cluster 1031‐1159 of TRRAP Gene: Expanding the Phenotype of Developmental Delay With or Without Dysmorphic Facies and Autism

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The transformation/transcription domain‐associated protein (TRRAP) gene encodes a large multidomain protein, a member of the phosphatidylinositol 3‐kinase‐related kinase (PIKK) family. TRRAP is a component of the histone acetyltransferase (HAT) complex, and it plays an important role in gene transcription, DNA repair, and cell‐cycle regulation.
Roseli Maria Zechi‐Ceide, Vinicius Contrucci Dantas Segarra, Siulan Vendramini‐Pittoli, Henrique Regonaschi Serigatto, Luiza Virmond, Heloisa Marcelina da Cunha Palhares, Fernanda Jehee, Ana Cristina Victorino Krepischi, Carla Rosenberg, Carlos Henrique Paiva Grangeiro, Nancy Mizue Kokitsu‐Nakata   +10 more
wiley   +1 more source

Hereditary angioedema due to C1 inhibitor deficiency: real-world experience from the Icatibant Outcome Survey in Spain. [PDF]

Allergy Asthma Clin Immunol, 2021
Guilarte M, Sala-Cunill A, Baeza ML, Cabañas R, Hernández MD, Ibañez E, de Larramendi CH, Lleonart R, Lobera T, Marqués L, de San Pedro BS, Botha J, Andresen I, Caballero T, IOS Study Group.   +14 more
europepmc   +1 more source

A multicentre evaluation of the diagnostic efficiency of serological investigations for C1 inhibitor deficiency

, 2002
Mark Gompels, R J Lock, James P. Morgan, J R Osborne, Alex Brown, Paul Virgo   +5 more
openalex   +1 more source

Clinical Characteristics and Management of Angioedema Attacks in Polish Adult Patients with Hereditary Angioedema Due to C1-Inhibitor Deficiency. [PDF]

J Clin Med, 2021
Piotrowicz-Wójcik K, Bulanda M, Juchacz A, Jamróz-Brzeska J, Gocki J, Kuziemski K, Pawłowicz R, Porebski G.   +7 more
europepmc   +1 more source