Results 201 to 210 of about 26,472 (244)
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Autoimmune C1 Inhibitor Deficiency and Angioedema
Dermatology, 2009C1 inhibitor (C1-INH) deficiency results in bouts of mucocutaneous edema and may be inherited (hereditary angioedema) or acquired (acquired angioedema). The syndrome of acquired angioedema, characterized by the adult onset of angioedema and by the lack of evidence of inheritance of the disease, may be associated with lymphoproliferative or other ...
R, Valsecchi +3 more
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Angioedema associated with C1 inhibitor deficiency
Clinical Reviews in Allergy & Immunology, 1999Angioedema associated with C1 INH deficiency requires diagnosis as soon as the first symptoms of the disease are manifest, and laboratory measurement of complement component levels at the least suspicion, in order to institute preventive and curative treatments.
J, Laurent, M T, Guinnepain
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The metabolism of C1 inhibitor and C1q in patients with acquired C1-inhibitor deficiency
Journal of Allergy and Clinical Immunology, 1986The metabolism of 125I-labeled C1 inhibitor (C1INH) and C1q was studied in five patients with B cell lymphoproliferative disorders, C1INH deficiency, and angioedema. C1INH catabolism was markedly accelerated in these patients. The fractional catabolic rate (FCR) was 0.053 of the plasma pool per hour compared to that of normal subjects (0.025) or ...
J, Melamed +3 more
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Danazol® and C1 Esterase Inhibitor Deficiency
Annals of Internal Medicine, 1978Excerpt To the editor: We write to confirm the findings of Hauptmann and associates (1) on the therapy of acquired C1 esterase inhibitor (C1 INH) deficiency with Danazol®.
S H, Cohen, S M, Koethe
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C1 inhibitor deficiency: diagnosis.
Clinical and Experimental Dermatology, 2005This is the first of two articles on C1 inhibitor deficiency based on a recent UK consensus document covering diagnosis and management of the disorder in both adults and children. This paper focuses on diagnosis of this disorder.
M M, Gompels, R J, Lock
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Acute consumption of C1 inhibitor in a patient with acquired C1-inhibitor deficiency syndrome
Journal of Allergy and Clinical Immunology, 1991Acquired C1-inhibitor (C1 INH) deficiency is usually found in association with an underlying disease that is believed to be responsible for increased C1 INH catabolism, ultimately leading to the development of C1 INH deficiency. We report a remarkable patient with acquired C1 INH deficiency in whom a unique progression of complement- and contact-system
B L, Zuraw, L C, Altman
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Treatment of Acquired C1-Inhibitor Deficiency with Danazol
Annals of Internal Medicine, 1977Excerpt Hereditary angioedema is characterized by a marked deficiency of the inhibitor of activated first component of complement (C1 inhibitor).
G, Hauptmann +4 more
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The Acquired Deficiency of C1-Inhibitor: Lymphoproliferation and Angioedema
Current Molecular Medicine, 2010Acquired deficiency of C1 inhibitor (C1-INH) with angioedema symptoms (acquired angioedema, AAE) is characterized by local increase in vascular permeability (angioedema) of the skin and the gastrointestinal and oro-pharyngo-laryngeal mucosa. The mediator of symptoms is bradykinin, a potent vasoactive peptide, released from high molecular weight ...
M. Cicardi, A. Zanichelli
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Factor VIIa in Patients with C1-Inhibitor Deficiency
Thrombosis and Haemostasis, 1995SummaryIn hereditary angioedema (HAE), normal C1-inhibitor (CI-INH) is low and the contact system aetivated. Recently, the findings of a tissue factor mutant selectively deficient in promoting the conversion of FVII to FVIIa, but with retained cofactor for FVIIa, made it possible to examine reliably the pre-existing content of FVIIa in HAH patients ...
E W, Nielsen +3 more
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Angioedema due to C1 inhibitor deficiency in 2010
Internal and Emergency Medicine, 2010Angioedema is a recurrent, non-pitting, non-pruritic, self-limiting swelling due to transient increase of endothelial permeability in the capillaries of the deep cutaneous and mucosal layers. Two main groups of angioedema should be distinguished based on the response to treatment: those responding to antihistamine and those that do not.
M. Cicardi, A. Zanichelli
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