Porcine kidney xenotransplantation: From primate models to clinical reality
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo +3 more
wiley +1 more source
Clinical validity of dried blood spot assay for the measurement of functional C1 inhibitor in angioedema due to C1 inhibitor deficiency. [PDF]
Bernstein JA +6 more
europepmc +1 more source
Lanadelumab in a kidney transplant patient with hereditary angioedema due to C1-inhibitor deficiency and high cardiovascular risk - a case report. [PDF]
Gidaro A +8 more
europepmc +1 more source
A real-world study of hereditary angioedema patients due to C1 inhibitor deficiency treated with danazol in the Brazilian Public Health System. [PDF]
Ritter AMV +6 more
europepmc +1 more source
Rare connective tissue diseases in patients with C1-inhibitor deficiency hereditary angioedema: first evidence on prevalence and distribution from a large Italian cohort study. [PDF]
Triggianese P +21 more
europepmc +1 more source
An air‐stable, easily prepared, bifunctional Cu(II)/imidazolium complex enables highly enantioselective α‐alkylation of 1,3‐dicarbonyls with outstanding productivity (TON up to 1740). Highlights include broad electrophile scope spanning π‐activated and nonactivated reagents, stereo‐retentive allylation, simple catalyst synthesis, and efficient catalyst
Johanna Haußmann +8 more
wiley +1 more source
ABSTRACT The global trend toward sustainable and intensified bioprocesses is driving innovation in the design and scalable synthesis of liposomal nanocarriers, a cornerstone of modern drug delivery. For decades, these nanosystems have relied exclusively on polyethylene glycol (PEG) for their sustained circulation in vivo, but they are currently ...
Chandra Has
wiley +1 more source
Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz +3 more
wiley +1 more source
Acute Abdominal Pain as the Initial Presentation of an Acquired C1 Inhibitor Deficiency. [PDF]
Pinto AR, Carolino F.
europepmc +1 more source

