Results 271 to 280 of about 98,834 (305)

Factor VIIa in Patients with C1-Inhibitor Deficiency

Thrombosis and Haemostasis, 1995
SummaryIn hereditary angioedema (HAE), normal C1-inhibitor (CI-INH) is low and the contact system aetivated. Recently, the findings of a tissue factor mutant selectively deficient in promoting the conversion of FVII to FVIIa, but with retained cofactor for FVIIa, made it possible to examine reliably the pre-existing content of FVIIa in HAH patients ...
E W, Nielsen, J, Morrissey, J O, Olsen, B, Osterud   +3 more
openaire   +2 more sources

Angioedema due to C1 inhibitor deficiency in 2010

Internal and Emergency Medicine, 2010
Angioedema is a recurrent, non-pitting, non-pruritic, self-limiting swelling due to transient increase of endothelial permeability in the capillaries of the deep cutaneous and mucosal layers. Two main groups of angioedema should be distinguished based on the response to treatment: those responding to antihistamine and those that do not.
M. Cicardi, A. Zanichelli
openaire   +2 more sources

Lupus Erythematosus Associated with C1 Inhibitor Deficiency

The Journal of Dermatology, 2002
AbstractWe report here a patient with skin lesions of lupus erythematosus (LE) associated with a type 1 hereditary C1 inhibitor deficiency. She had not experienced any episodes of angioedema. A histological examination of the affected skin lesions demonstrated liquefaction of the basal cell layer in the perifollicule. Direct immunofluorescence staining
Masayo, Koide, Shigeho, Shirahama, Yoshiki, Tokura, Masahiro, Takigawa, Masakatsu, Hayakawa, Fukumi, Furukawa   +5 more
openaire   +2 more sources

Where we are with acquired angioedema due to C1 inhibitor deficiency: A systematic literature review.

Clinical Immunology, 2021
Yiyun Shi, Chen Wang
semanticscholar   +1 more source

C1 inhibitor deficiency

Clinical and Experimental Dermatology, 2005
M, Darling, M L, Price
openaire   +2 more sources

Angioedema and C1 inhibitor deficiency.

Annals of allergy, 1992
Deficiency of C1 inhibitor resulting in episodes of angioedema causes significant morbidity and mortality in affected patients, yet often goes undiagnosed for years. As biochemical understanding of the disorder has improved, competing theories for the pathophysiologic mechanism of angioedema have emerged.
N A, Orfan, G B, Kolski
openaire   +1 more source

The C1 inhibitor deficiency. A review.

European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1993
C1 inhibitor (C1I), a member of the serine protease inhibitor superfamily, is the principal regulator of the activation classical pathway of complement by reducing the proteolytic activity of activated C1r and C1s. A deficiency of active C1 inhibitor is the most commonly identified genetic defect of the complement system.
openaire   +1 more source

Cardiac Surgery and C1-Inhibitor Deficiency

Journal of Cardiothoracic and Vascular Anesthesia, 2014
Thiên-Nga, Chamaraux-Tran, François, Levy, Matthieu, Zappaterra, Joëlle, Goetz, Bernard, Goichot, Annick, Steib   +5 more
openaire   +2 more sources

Angioedema Due to Acquired Deficiency of C1-Inhibitor: A Cohort Study in Spain and a Comparison With Other Series

Journal of Allergy and Clinical Immunology: in Practice, 2022
TERESA González-Quevedo, TERESA Caballero, Mar Guilarte   +2 more
exaly  

Inherited C1 inhibitor deficiency.

Complement and inflammation, 1989
The paper reports our experience of a 15-year follow-up of 179 patients with hereditary angioedema (HAE). The disease is transmitted as an autosomal dominant trait and two variants have been described: type I characterized by functional and antigenic C1-inhibitor (C1-INH) deficiency and type II with normal or upper normal C1-INH antigenic levels but no
openaire   +1 more source