Results 91 to 100 of about 57,775 (215)

Elevated Serum Complement C1q Levels After Traumatic Brain Injury [Letter]

Neuropsychiatric Disease and Treatment, 2022
Wellingson Silva Paiva,1,2 Josimar Ortiz,1 Robson Luis Amorim2 1Division of Neurosurgery, Department of Neurology, Hospital das Clínicas da Faculdade de Medicina, University of São Paulo, São Paulo, Brazil; 2LIM 62, Laboratory of ...
Paiva WS, Ortiz J, Amorim RL
doaj  

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID

Immunology, EarlyView.
The complement cascade, a series of blood proteins that assists in the recognition and neutralisation of pathogens, either independently or in conjunction with antibodies, is persistently activated in patients with long COVID. We found that blood plasma samples from patients with long COVID contained elevated concentrations of the mannan‐binding lectin‐
Samuel B. K. Keat, Priyanka Khatri, Youssif M. Ali, Chanuka H. Arachchilage, Gregory Demopulos, Kirsten Baillie, Kelly L. Miners, Kristin Ladell, Samantha A. Jones, Helen E. Davies, David A. Price, Wioleta M. Zelek, B. Paul Morgan, Wilhelm J. Schwaeble, Nicholas J. Lynch   +14 more
wiley   +1 more source

Elevated Serum Complement C1q Levels After Traumatic Brain Injury and Its Association with Poor Prognosis

Neuropsychiatric Disease and Treatment, 2022
Xin-Jiang Yan,1 Yang-Bo Li,1 Wei Liu,1 Hua-Yong Wu,2 Guo-Feng Yu1 1Department of Neurosurgery, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital, Quzhou, People’s Republic of China; 2Neurosurgical Intensive Care Unit,
Yan XJ, Li YB, Liu W, Wu HY, Yu GF
doaj  

Anti-C1q Antibodies as Occurring in Systemic Lupus Erythematosus Could Be Induced by an Epstein-Barr Virus-Derived Antigenic Site

Frontiers in Immunology, 2019
Previous infection with Epstein-Barr virus (EBV) is believed to trigger autoimmunity and to drive autoantibody generation as occurring in patients with systemic lupus erythematosus (SLE). Complement C1q and autoantibodies targeting it (anti-C1q) are also
Kinga Csorba, Lucia A. Schirmbeck, Eylul Tuncer, Camillo Ribi, Pascale Roux-Lombard, Carlo Chizzolini, Uyen Huynh-Do, Dominique Vanhecke, Marten Trendelenburg   +8 more
doaj   +1 more source

Tkachenko polarons in vortex lattices

, 2013
We analyze the properties of impurities immersed in a vortex lattice formed by ultracold bosons in the mean field quantum Hall regime. In addition to the effects of a periodic lattice potential, the impurity is dressed by collective modes with parabolic ...
Bagnato, V. S., Caracanhas, M. A., Pereira, R. G.   +2 more
core   +1 more source

Serum CTRP3 and CysC correlate with glucose, lipid, and bone metabolism in elderly patients with type 2 diabetes mellitus complicated with osteoporosis

Journal of Diabetes Investigation, EarlyView.
Serum levels of CTRP3 and CysC in elderly patients with T2DM and OP are closely associated with glucose‐lipid metabolism, bone mineral density, and bone metabolism markers. Combined detection of these two markers can assist in distinguishing OP in elderly patients with T2DM.
Yi‐Peng Wang, Yong Wang, Tao Chen, Gang Chen, Ze‐Yu Yang   +4 more
wiley   +1 more source

The Role of Complement in Synaptic Pruning and Neurodegeneration

ImmunoTargets and Therapy, 2021
Angela Gomez-Arboledas,1 Munjal M Acharya,2,3 Andrea J Tenner1,4,5 1Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, USA; 2Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA,
Gomez-Arboledas A, Acharya MM, Tenner AJ
doaj  

High prevalence of anti-C1q antibodies in biopsy-proven active lupus nephritis [PDF]

, 2017
Background. Anti-C1q antibodies (anti-C1q) have been shown to correlate positively with systemic lupus erythematosus (SLE) nephritis. Several clinical studies indicated a high negative predictive value, suggesting that active lupus nephritis is rarely ...
Frémeaux-Bacchi, Véronique, Honsova, Eva, Jancova, Eva, Lopez-Trascasa, Margarita, Martinez-Ara, Jorge, Moll, Solange, Picazo, Mari Luz, Potlukova, Eliska, Regenass, Stephan, Sadallah, Salima, Schifferli, Jürg, Tesar, Vladimir, Trendelenburg, Marten   +12 more
core  

scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions

Journal of the European Academy of Dermatology and Venereology, EarlyView.
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu, Agata Kurowski, Malini P. Naidu, Jonas Adalsteinsson, Shane A. Meehan, Natalia Alkon, Lauren R. Port, Sumanth Chennareddy, Emry R. Cohenour, Grace Christensen, Jonah Shulman, Nicholas Gulati, Constanze Jonak, Patrick M. Brunner   +13 more
wiley   +1 more source