Results 151 to 160 of about 70,452 (309)
C1q nephropathy- unity in diversity.
Journal of renal injury prevention, 2013 Implication for health policy/practice/research/medical educationC1q nephropathy refers to a disorder in which C1q deposits are seen in mesangium on immunofluorescence microscopy and mesangial electron dense deposits on electron microscopy. The diagnosis of C1q nephropathy is based on demonstration of intense C1q (dominant or co-dominant) positivity ...
openaire +2 more sources
Epilepsia, EarlyView.Abstract Objective Accumulating evidence indicates that aberrant C1q‐C3 complement signaling in microglia and astrocytes drives synaptic dysfunction and neuronal loss. C1q‐mediated synaptic dysfunction disrupts neuronal circuitry balance and can lead to network hyperexcitability in epilepsy.
Yoonyi Jeong +5 more
wiley +1 more source
Asociación del anticuerpo anti-C1q con las manifestaciones clínicas, hematológicas e inmunológicas en el Lupus Eritematoso Sistémico : Estudio observacional retrospectivo de 135 casos [PDF]
, 2012 : Las concentraciones de anticuerpo anti-C1q están elevadas en los pacientes afectados de LES. Según algunos estudios la presencia de este anticuerpo está asociada a la nefropatía lúpica, sin embargo en otros estudios esta relación no se comprobó.
Córica, María Emilia +2 more
core
The FEBS Journal, EarlyView.How the structure of HRK, a member of the BCL‐2 protein family, contributes to its function is poorly understood. Functional analysis of HRK mutants reveals that HRK induces apoptosis in a BH3‐domain‐dependent, but transmembrane‐domain‐independent, manner. The transmembrane domain localises HRK to mitochondria, but alone is insufficient.
Louise E. King +2 more
wiley +1 more source
Amino acid sequence of the N-terminal forty-two amino acid residues of the C chain of subcomponent C1q of the first component of human complement [PDF]
, 1977 K.B.M. Reid
openalex +1 more source
Complement Component C1q as Serum Biomarker to Detect Active Tuberculosis
Frontiers in Immunology, 2018 Background: Tuberculosis (TB) remains a major threat to global health. Currently, diagnosis of active TB is hampered by the lack of specific biomarkers that discriminate active TB disease from other (lung) diseases or latent TB infection (LTBI ...
R. Lubbers +19 more
semanticscholar +1 more source
Antibody Polyreactivity: A Challenger of Immune Paradigms
Immunology, EarlyView.This review article discusses the definition and functions of polyreactive antibodies, as well as their physiological roles. It also presents the concept of polyreactivity as a challenger of immunological dogmas. ABSTRACT Polyreactivity refers to the ability of antibodies to bind multiple unrelated antigens, encompassing polyspecificity and promiscuity.
Anastas D. Pashov, Jordan D. Dimitrov
wiley +1 more source
Journal of Transplantation, 2016 The aim of the present study was to describe the association of positive flow cross match (FXM) and C1q-SAB. Methods. In this observational, cross-sectional, and comparative study, patients included had negative AHG-CDC-XM and donor specific antibodies ...
José M. Arreola-Guerra +10 more
doaj +1 more source
On the Interaction of Rabbit C1q with Sheep and Rabbit Immune Complexes [PDF]
, 1979 Paul A. Liberti +3 more
openalex +1 more source
The Subgingival Host–Microbial Landscape in Mothers With Periodontitis and Their At‐Risk Offspring
Journal of Clinical Periodontology, EarlyView.ABSTRACT Aim To evaluate the subgingival proteome and microbiome of mothers with periodontitis and their offspring, thereby assessing signatures of periodontal diseases. Methods Forty participants in four groups were included: mothers with periodontitis and their offspring, as well as periodontally healthy mothers and their offspring.
Hélvis E. S. Paz +8 more
wiley +1 more source