Results 251 to 260 of about 683,642 (281)

Hemophilic factor VIII C1- and C2-domain missense mutations and their modeling to the 1.5-angstrom human C2-domain crystal structure

Blood, 2000
AbstractFactor VIII C domains contain key binding sites for von Willebrand factor (vWF) and phospholipid membranes. Hemophilic patients were screened for factor VIII C-domain mutations to provide a well-characterized series. Mutated residues were localized to the high-resolution C2 structure and to a homology model of C1.
M L, Liu, B W, Shen, S, Nakaya, K P, Pratt, K, Fujikawa, E W, Davie, B L, Stoddard, A R, Thompson   +7 more
openaire   +2 more sources

The AD3 locus of synaptotagmin-1 C2 domains modulates domain stability

Biophysical Journal
Synaptotagmin-1 (syt1) functions as the Ca2+-dependent sensor that triggers the rapid and synchronous release of neurotransmitters from neurotransmitter-containing vesicles during neuronal exocytosis. The syt1 protein has two homologous tandem C2 domains that interact with phospholipids in a Ca2+-dependent manner.
Matthew J, Dominguez, Anthony A, Bui, Johanna, Villarreal, Adam, Snow, Souvic, Karmakar, Faraz M, Harsini, Patrick J, Rock, Anne M, Rice, Kerry L, Fuson, R Bryan, Sutton   +9 more
openaire   +2 more sources

Role of C2 domain proteins during synaptic vesicle exocytosis

Biochemical Society Transactions, 2010
Neurotransmitter release is mediated by the fusion of synaptic vesicles with the presynaptic plasma membrane. Fusion is triggered by a rise in the intracellular calcium concentration and is dependent on the neuronal SNARE (soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptor) complex.
openaire   +3 more sources

Ferroelectric domain walls for nanotechnology

Nature Reviews Materials, 2021
Dennis Meier, Sverre M Selbach
exaly  

Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

Cell, 2021
Swathi Shrihari, Pavlo Gilchuk, Laura A Vanblargan   +2 more
exaly  

C2 Domain

2006
openaire   +2 more sources

Controllable electrical, magnetoelectric and optical properties of BiFeO3 via domain engineering

Progress in Materials Science, 2022
Yiqian Liu, Yao Wang, Shun Li
exaly  

C2 Domain

2020
openaire   +1 more source

N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2

Cell, 2021
Matthew McCallum, Anna De Marco, Florian A Lempp   +2 more
exaly  

C2-Domains in Ca2+-Signaling

2003
Thomas C. Südhof, Josep Rizo
openaire   +1 more source