Results 41 to 50 of about 4,044,136 (204)

The Vesicle Priming Factor CAPS Functions as a Homodimer via C2 Domain Interactions to Promote Regulated Vesicle Exocytosis

Journal of Biological Chemistry, 2016
Neurotransmitters and peptide hormones are secreted by regulated vesicle exocytosis. CAPS (also known as CADPS) is a 145-kDa cytosolic and peripheral membrane protein required for vesicle docking and priming steps that precede Ca2+-triggered vesicle ...
Matt Petrie, Joseph M. Esquibel, Greg Kabachinski, Stephanie Maciuba, Hirohide Takahashi, J. Michael Edwardson, X. Thomas, F. J. Martín   +7 more
semanticscholar   +1 more source

A second-order continuity domain-decomposition technique based on integrated Chebyshev polynomials for two-dimensional elliptic problems [PDF]

, 2008
This paper presents a second-order continuity non-overlapping domain decomposition (DD) technique for numerically solving second-order elliptic problems in two-dimensional space.
Mai-Duy, Nam, Tran-Cong, Thanh
core   +2 more sources

Synaptotagmins: C2-Domain Proteins That Regulate Membrane Traffic [PDF]

Neuron, 1996
We wish to thank Drs. M. S. Brown, J. L. Goldstein, Y. Goda, R. Jahn, E. Kandel, E. Liebe, and C. F. Stevens for invaluable advice and discussions. The work described in this review was partially supported by the National Institutes of Health, Human Frontier Science Project, and W. M. Keck Foundation.
Südhof, Thomas C, Rizo, Josep
openaire   +2 more sources

Selection of Software Product Line Implementation Components Using Recommender Systems: An Application to Wordpress [PDF]

, 2019
In software products line (SPL), there may be features which can be implemented by different components, which means there are several implementations for the same feature.
Benavides Cuevas, David Felipe, Galindo Duarte, José Ángel, García Gutiérrez, Jorge, Rodas Silva, Jorge Luis   +3 more
core   +1 more source

MCTP is an ER-resident calcium sensor that stabilizes synaptic transmission and homeostatic plasticity. [PDF]

, 2017
Presynaptic homeostatic plasticity (PHP) controls synaptic transmission in organisms from Drosophila to human and is hypothesized to be relevant to the cause of human disease.
Davis, Graeme W, Dickman, Dion K, Fetter, Richard D, Genç, Özgür, Ma, Wenpei, Tong, Amy   +5 more
core   +2 more sources

Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes*

Journal of Biological Chemistry, 2015
Background: Perforin is a critical component of immune homeostasis, responsible for clearing virally infected cells. Results: The molecular details of calcium binding by the perforin C2 domain are revealed.
H. Yagi, P. Conroy, E. Leung, R. Law, J. Trapani, I. Voskoboinik, J. Whisstock, R. Norton   +7 more
semanticscholar   +1 more source

A C2 domain containing plasma membrane protein of Plasmodium falciparum merozoites mediates calcium-dependent binding and invasion to host erythrocytes

Journal of Microbiology, Immunology and Infection, 2023
Background: Invasion of red blood cells by Plasmodium falciparum merozoites is governed by multiple receptor–ligand interactions which are critical for bridging the two cells together.
Akshay Munjal, Deepika Kannan, Shailja Singh   +2 more
doaj   +1 more source

Critical thermodynamics of three-dimensional chiral model for N > 3 [PDF]

, 2003
The critical behavior of the three-dimensional $N$-vector chiral model is studied for arbitrary $N$. The known six-loop renormalization-group (RG) expansions are resummed using the Borel transformation combined with the conformal mapping and Pad\'e ...
A. I. Sokolov, A. Lascialfari, A. Peles, A. Pelissetto, A. Pelissetto, A. Pelissetto, A. Pelissetto, A. Pelissetto, D. Loison, D. Loison, E. H. Boubchear, G. Parisi, G. Zumbach, H. K. Janssen, H. Kadowaki, H. Kadowaki, H. Kawamura, H. Kawamura, H. Kawamura, H. Kawamura, J. A. Gracey, J. A. Gracey, J. C. Le Guillou, J. C. Le Guillou, J. M. Carmona, M. F. Collins, M. Fiebig, M. Itakura, M. Kukovic, M. Tissier, M. Tissier, M. Tissier, P. Azaria, P. Azaria, P. Calabrese, P. Calabrese, P. Calabrese, P. Calabrese, P. Parruccini, R. Folk, S. A. Antonenko, S. A. Antonenko, S. Sachdev, S. Sachdev, T. E. Mason, V. P. Plakhty, V. P. Plakhty, Y. Ajiro   +47 more
core   +1 more source

PTEN Phosphatase-Independent Maintenance of Glandular Morphology in a Predictive Colorectal Cancer Model System

Neoplasia: An International Journal for Oncology Research, 2013
Organotypic models may provide mechanistic insight into colorectal cancer (CRC) morphology. Three-dimensional (3D) colorectal gland formation is regulated by phosphatase and tensin homologue deleted on chromosome 10 (PTEN) coupling of cell division cycle
Ishaan C. Jagan, Ravi K. Deevi, Aliya Fatehullah, Rebecca Topley, Joshua Eves, Michael Stevenson, Maurice Loughrey, Kenneth Arthur, Frederick Charles Campbell   +8 more
doaj   +1 more source

The role of phosphatidylserine on the membrane in immunity and blood coagulation

Biomarker Research, 2022
The negatively charged aminophospholipid, phosphatidylserine (PtdSer), is located in the inner leaflet of the plasma membrane in normal cells, and may be exposed to the outer leaflet under some immune and blood coagulation processes.
Jiao Wang, Changxin Yu, Junyi Zhuang, Wenxin Qi, Jiawen Jiang, Xuanting Liu, Wanwei Zhao, Yiyang Cao, Hao Wu, Jingxuan Qi, Robert Chunhua Zhao   +10 more
doaj   +1 more source