Results 31 to 40 of about 683,642 (281)
At sites of vascular damage, factor VIII (fVIII) is proteolytically activated by thrombin and binds to activated platelet surfaces with activated factor IX (fIXa) to form the intrinsic “tenase” complex. Previous structural and mutational studies of fVIII
Shaun C. Peters +9 more
doaj +1 more source
Crystal structures of the human Dysferlin inner DysF domain [PDF]
Background: Mutations in dysferlin, the first protein linked with the cell membrane repair mechanism, causes a group of muscular dystrophies called dysferlinopathies.
Cole, Ambrose R. +4 more
core +1 more source
Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b [PDF]
Mutations in the protein dysferlin, a member of the ferlin family, lead to limb girdle muscular dystrophy type 2B and Myoshi myopathy. The ferlins are large proteins characterised by multiple C2 domains and a single C-terminal membrane-spanning helix ...
Achanzar +70 more
core +1 more source
Membrane proteins are broadly classified as transmembrane (TM) or peripheral, with functions that pertain to only a single bilayer at a given time. Here, we explicate a class of proteins that contain both transmembrane and peripheral domains, which we ...
Michael Overduin +4 more
doaj +1 more source
Crossover between different regimes of inhomogeneous superconductivity in planar superconductor-ferromagnet hybrids [PDF]
We studied experimentally the effect of a stripe-like domain structure in a ferromagnetic BaFe_{12}O_{19} substrate on the magnetoresistance of a superconducting Pb microbridge.
Aladyshkin, A. Yu. +7 more
core +3 more sources
C2‐domain containing calcium sensors in neuroendocrine secretion [PDF]
The molecular mechanisms for calcium‐triggered membrane fusion have long been sought for, and detailed models now exist that account for at least some of the functions of the many proteins involved in the process. Key players in the fusion reaction are a group of proteins that, upon binding to calcium, trigger the merger of cargo‐filled vesicles with ...
Pinheiro, Paulo S +2 more
openaire +3 more sources
Synaptotagmins: C2-Domain Proteins That Regulate Membrane Traffic [PDF]
We wish to thank Drs. M. S. Brown, J. L. Goldstein, Y. Goda, R. Jahn, E. Kandel, E. Liebe, and C. F. Stevens for invaluable advice and discussions. The work described in this review was partially supported by the National Institutes of Health, Human Frontier Science Project, and W. M. Keck Foundation.
Südhof, Thomas C, Rizo, Josep
openaire +2 more sources
A second-order continuity domain-decomposition technique based on integrated Chebyshev polynomials for two-dimensional elliptic problems [PDF]
This paper presents a second-order continuity non-overlapping domain decomposition (DD) technique for numerically solving second-order elliptic problems in two-dimensional space.
Mai-Duy, Nam, Tran-Cong, Thanh
core +2 more sources
Selection of Software Product Line Implementation Components Using Recommender Systems: An Application to Wordpress [PDF]
In software products line (SPL), there may be features which can be implemented by different components, which means there are several implementations for the same feature.
Benavides Cuevas, David Felipe +3 more
core +1 more source
Background: Invasion of red blood cells by Plasmodium falciparum merozoites is governed by multiple receptor–ligand interactions which are critical for bridging the two cells together.
Akshay Munjal +2 more
doaj +1 more source

