Results 41 to 50 of about 157,920 (289)
The role of phosphatidylserine on the membrane in immunity and blood coagulation
Biomarker Research, 2022 The negatively charged aminophospholipid, phosphatidylserine (PtdSer), is located in the inner leaflet of the plasma membrane in normal cells, and may be exposed to the outer leaflet under some immune and blood coagulation processes.
Jiao Wang +10 more
doaj +1 more source
C2‐domain containing calcium sensors in neuroendocrine secretion [PDF]
Journal of Neurochemistry, 2016 The molecular mechanisms for calcium‐triggered membrane fusion have long been sought for, and detailed models now exist that account for at least some of the functions of the many proteins involved in the process. Key players in the fusion reaction are a group of proteins that, upon binding to calcium, trigger the merger of cargo‐filled vesicles with ...
Pinheiro, Paulo S +2 more
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Calcium triggers an intramolecular association of the C2 domains in synaptotagmin [PDF]
Proceedings of the National Academy of Sciences, 2000 Synaptotagmin I is a critical component of the synaptic machinery that senses calcium influx and triggers synaptic vesicle fusion and neurotransmitter release. Fluorescence resonance energy transfer studies conducted on synaptotagmin demonstrate that calcium concentrations required for fusion induce a conformational change (EC ...
R A, García, C E, Forde, H A, Godwin
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DUF581 is plant specific FCS-like zinc finger involved in protein-protein interaction. [PDF]
PLoS ONE, 2014 Zinc fingers are a ubiquitous class of protein domain with considerable variation in structure and function. Zf-FCS is a highly diverged group of C2-C2 zinc finger which is present in animals, prokaryotes and viruses, but not in plants.
Muhammed Jamsheer K, Ashverya Laxmi
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, 2022 A. C2-FerA domain schematic showings the secondary structure connectivity and the large insertion of the β4–5 FerA subdomain. B. SDS-PAGE showing the purified dysferlin C2-FerA domain versus molecular weight size markers. C.
Jon J. McCord (11977550) +2 more
core +1 more source
BMC Cell Biology, 2009 Background Ubiquitination serves multiple cellular functions, including proteasomal degradation and the control of stability, function, and intracellular localization of a wide variety of proteins.
Lalouel Jean-Marc +4 more
doaj +1 more source
, 2013 Plant C2 domain proteins play important roles in diverse cellular processes including growth, development, and membrane targeting, as well as in abiotic and biotic stress adaptations by sensing intracellular Ca2+ signals.
Y. T. Yu +9 more
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Functional and Biochemical Analysis of the C2 Domains of Synaptotagmin IV [PDF]
Molecular Biology of the Cell, 1999 Synaptotagmins (Syts) are a family of vesicle proteins that have been implicated in both regulated neurosecretion and general membrane trafficking. Calcium-dependent interactions mediated through their C2 domains are proposed to contribute to the mechanism by which Syts trigger calcium-dependent neurotransmitter release. Syt IV is a novel member of the
D M, Thomas +3 more
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, 2006 Follicle consists of an oocyte and a lot of surrounding follicular cells, and significant interactions exist between the oocyte and the somatic cells. In this study, a novel cDNA has been screened from a subtractive cDNA library between tail bud embryos ...
Ji, GD +5 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source