Results 181 to 190 of about 37,904 (214)
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Isolation and characterization of the C3b-binding entity of C3b-receptor from human erythrocytes
Immunology Letters, 1982Applying 2 M KBr, membranes of Ehu were solubilized. By C3-affinity chromatography an activity could be isolated that inhibited the immune adherence reaction and C3b-dependent rosette formation. Since this material did not agglutinate EAC14oxy23b we termed it monovalent C3b receptor (mC3bR).
Mussel, HH +5 more
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Vox Sanguinis, 1977
Substitution of trypsin for Konglutinogen-activating factor (KAF) in the procedure for cleaving C3d from C3-C3b substrate produced a relatively heterogeneous low-molecular-weight fraction (C3d-Tryp) which differed in a number of ways from the KAF-mediated cleavage product (C3d-KAF).
J, Freedman +3 more
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Substitution of trypsin for Konglutinogen-activating factor (KAF) in the procedure for cleaving C3d from C3-C3b substrate produced a relatively heterogeneous low-molecular-weight fraction (C3d-Tryp) which differed in a number of ways from the KAF-mediated cleavage product (C3d-KAF).
J, Freedman +3 more
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Scandinavian Journal of Immunology, 1985
Macrophages have been shown to produce C3 and to hear Fc receptors (FcR). and besides The various C3 receptors, they possess C3b acceptors (C3bA) as well as surface proteases capable of cleaving C3. Using the immune adherence method, we demonstrated that the amount of covalently fixed (i.e., C3bA‐bound) C3h is markedly increased upon cell stimulation ...
Z, Fábry, A, Erdei, J, Gergely
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Macrophages have been shown to produce C3 and to hear Fc receptors (FcR). and besides The various C3 receptors, they possess C3b acceptors (C3bA) as well as surface proteases capable of cleaving C3. Using the immune adherence method, we demonstrated that the amount of covalently fixed (i.e., C3bA‐bound) C3h is markedly increased upon cell stimulation ...
Z, Fábry, A, Erdei, J, Gergely
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The Journal of Immunology, 1979
Abstract In previous studies of the role of IgG and C3b in opsonization, C3b has not been present on the target particle in the complete absence of other serum proteins. We have developed a system in which C3b alone is present on the particle, using trypsin cleavage of purified C3. Sheep erythrocytes (E) coated with trypsin-generated C3b
S L, Newman, R B, Johnston
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Abstract In previous studies of the role of IgG and C3b in opsonization, C3b has not been present on the target particle in the complete absence of other serum proteins. We have developed a system in which C3b alone is present on the particle, using trypsin cleavage of purified C3. Sheep erythrocytes (E) coated with trypsin-generated C3b
S L, Newman, R B, Johnston
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Clinical and experimental immunology, 1980
Using fluorescein-labelled S. typhi coated with C3b (FBC) the presence of a receptor for C3b in normal human glomeruli has been confirmed. A quantitative system, counting the number of FBC bound per unit area of glomerulus, has been developed. Experimental variables have been studied to determine optimal conditions for FBC binding.
L, Schrieber, R, Penny
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Using fluorescein-labelled S. typhi coated with C3b (FBC) the presence of a receptor for C3b in normal human glomeruli has been confirmed. A quantitative system, counting the number of FBC bound per unit area of glomerulus, has been developed. Experimental variables have been studied to determine optimal conditions for FBC binding.
L, Schrieber, R, Penny
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Nouvelle revue francaise d'hematologie, 1984
The cellular receptor for the C3b fragment of the third component of complement is a 205,000 molecular weight glycoprotein expressed by erythrocytes, polymorphonuclear leukocytes, monocytes, B lymphocytes, a subset of T lymphocytes and glomerular podocytes. The receptor molecule is a potent inhibitor of complement activation by both the alternative and
J, Cook, M, Kazatchkine
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The cellular receptor for the C3b fragment of the third component of complement is a 205,000 molecular weight glycoprotein expressed by erythrocytes, polymorphonuclear leukocytes, monocytes, B lymphocytes, a subset of T lymphocytes and glomerular podocytes. The receptor molecule is a potent inhibitor of complement activation by both the alternative and
J, Cook, M, Kazatchkine
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2018
The present invention relates to the fields of molecular biology, immunology, and medicine. More specifically, the present invention relates to a polypeptide that binds to C3b.
Clark, Simon +2 more
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The present invention relates to the fields of molecular biology, immunology, and medicine. More specifically, the present invention relates to a polypeptide that binds to C3b.
Clark, Simon +2 more
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The Journal of experimental medicine, 1973
IN THE PRESENT STUDY IT WAS SHOWN THAT NORMAL PERIPHERAL LYMPHOCYTES HAVE TWO DIFFERENT COMPLEMENT RECEPTORS: one for C3b (the immune adherence receptor) and one for C3b subsequent to its cleavage by C3b inactivator. The two receptors are not cross-reactive and were shown by tests with various antisera to be antigenically distinct.
G D, Ross +3 more
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IN THE PRESENT STUDY IT WAS SHOWN THAT NORMAL PERIPHERAL LYMPHOCYTES HAVE TWO DIFFERENT COMPLEMENT RECEPTORS: one for C3b (the immune adherence receptor) and one for C3b subsequent to its cleavage by C3b inactivator. The two receptors are not cross-reactive and were shown by tests with various antisera to be antigenically distinct.
G D, Ross +3 more
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The superfamily of C3b/C4b-binding proteins.
Federation proceedings, 1987The determination of primary structures by amino acid and nucleotide sequencing for the C3b-and/or C4b-binding proteins H, C4BP, CR1, B, and C2 has revealed the presence of a common structural element. This element is approximately 60 amino acids long and is repeated in a tandem fashion, commencing at the amino-terminal end of each molecule.
Kristensen, Torsten +5 more
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