Results 41 to 50 of about 6,779 (207)

Unique Biomarkers of Collagen Type III Remodeling Reflect Different Information Regarding Pathological Kidney Tissue Alterations in Patients with IgA Nephropathy

Biomolecules, 2023
Kidney fibrosis is the hallmark of chronic kidney disease (CKD) and is characterized by an imbalanced extracellular matrix (ECM) remodeling. Collagen type III is one of the main ECM components of the interstitial matrix of the kidney.
Nadja Sparding, Michaela Neprasova, Dita Maixnerova, Federica Genovese, Morten Asser Karsdal, Marek Kollar, Helena Koprivova, Zdenka Hruskova, Vladimir Tesar   +8 more
doaj   +1 more source

Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b

Journal of Molecular Biology, 2010
The human complement system plays an essential role in innate and adaptive immunity by marking and eliminating microbial intruders. Activation of complement on foreign surfaces results in proteolytic cleavage of complement component 3 (C3) into the ...
B. Garcia, K. Ramyar, Apostolia Tzekou, D. Ricklin, William J Mcwhorter, John D Lambris, B. Geisbrecht   +6 more
semanticscholar   +1 more source

Putative salivary protein biomarkers for the diagnosis of oral lichen planus: a case-control study

BMC Oral Health, 2018
Background Salivary protein biomarkers for screening and diagnosis of oral lichen planus (OLP) are not well-defined. The objective of this study was to identify putative protein biomarkers for OLP using proteomic approaches.
Sineepat Talungchit, Waranun Buajeeb, Chotima Lerdtripop, Rudee Surarit, Kongthawat Chairatvit, Sittiruk Roytrakul, Hiroaki Kobayashi, Yuichi Izumi, Siribang-on Piboonniyom Khovidhunkit   +8 more
doaj   +1 more source

Role of light and immunofluorescence microscopy to differentiate primary and secondary membranous nephropathy

Indian Journal of Pathology and Microbiology, 2022
Context: Membranous nephropathy (MN) causes nephrotic syndrome, mostly primary but may be associated with SLE, infections, cancer, or drug. Aims: To estimate clinical, serological, light microscopic, and direct immunofluorescence (DIF) findings to ...
Keya Basu, Moumita Sengupta, Sriranjan Mukherjee, Subhrajyoti Karmakar, Arpita Roychowdhury, Manimoy Bandopadhyay   +5 more
doaj   +1 more source

KORELASI KADAR KOMPLEMEN C3c, NT-proBNP DAN LEFT VENTRICLE EJECTION FRACTION (LVEF) PADA PENDERITA GAGAL JANTUNG [PDF]

, 2018
Pendahuluan. Gagal jantung merupakan masalah kesehatan di Indonesia. Data Riset Kesehatan Dasar 2013 menunjukkan estimasi penderita gagal jantung di Indonesia sebesar 530.068 orang.
Julious, NIM011428156305
core   +1 more source

Pembrolizumab‐Induced Subacute Cutaneous Lupus Erythematosus: A Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Subacute cutaneous lupus erythematosus (SCLE) is an increasingly recognized cutaneous immune‐related adverse event of immune checkpoint inhibitors. We report an 83‐year‐old woman who developed pruritic annular and polycyclic plaques 10 weeks after starting pembrolizumab for oropharyngeal squamous cell carcinoma.
Sebastiano Posenato, Alba Guglielmo, Lucia Mantovani, Aikaterini Kalpaktsoglou, Simone Cavaliere, Alessandro Borghi   +5 more
wiley   +1 more source

C3C levels in COPD patients and healthy controls.

, 2017
(A) Levels of C3C were measured in serum of patients with COPD (n = 68) and compared to levels in healthy controls (n = 11). Results are shown as geometric mean with 95% confidence intervals.
Morten Asser Karsdal (317796), Federica Genovese (651372), Daniel Guldager Kring Rasmussen (3633226), Jannie Marie Bülow Sand (3633223)   +3 more
core   +1 more source

Da-Yuan-Yin decoction polyphenol fraction attenuates acute lung injury induced by lipopolysaccharide

Pharmaceutical Biology, 2023
Context Da-Yuan-Yin is a Chinese traditional prescription.Objective This study explores the therapeutic effects of the Da-Yuan-Yin decoction polyphenol fraction (DYY-4) on acute lung injury (ALI) in mice induced by lipopolysaccharide (LPS).Materials and ...
Lengqiu Guo, Yun Yang, Jie Yuan, Huiling Ren, Xiaolei Huang, Meng Li, Long Xia, Xiaogang Jiang, Daofeng Chen, Jian Zhang   +9 more
doaj   +1 more source

Molecular dynamics simulations and fluorescence spectroscopy suggest reduced tryptophan‐to‐heme energy transfer facilitates lignin degradation in ClassII peroxidases

The FEBS Journal, EarlyView.
In lignin peroxidase and versatile peroxidase, low FRET from buried Trp to heme promotes long‐range electron transfer (LRET) from substrate to heme. This efficient electron flow is facilitated by reduced FRET competition. This mechanism likely evolved to enable the effective degradation of bulky, high‐redox‐potential lignin that cannot reach the enzyme'
Yi Ren, Dale Ang, Haluk Ertan, Anne Poljak, Janice R. Aldrich‐Wright, Wallace J. Bridge, Khawar Sohail Siddiqui   +6 more
wiley   +1 more source

Load capacity for walls built with C3C block system –flooding loads

, 2021
Floods are the natural disaster that causes the most deaths and economic damage in the world. Sweden has been relatively spared from casualties in connection with floods, but the material damage is significant.
Blomberg, Johan, Sörgårn, Alfred
core   +3 more sources