Results 31 to 40 of about 6,779 (207)

Complement in Renal Disease as a Potential Contributor to Arterial Hypertension

open access: yesKidney & Blood Pressure Research, 2021
Objective: Complement deposition is prevalent in kidney biopsies of patients with arterial hypertension and hypertensive nephropathy, but an association of hypertension and complement deposition or involvement of complement in the pathogenesis of ...
Lisa-Maren Fischer   +6 more
doaj   +1 more source

Development of a Novel Enzyme-Linked Immunosorbent Assay Targeting a Neo-Epitope Generated by Cathepsin-Mediated Turnover of Type III Collagen and Its Application in Chronic Obstructive Pulmonary Disease. [PDF]

open access: yesPLoS ONE, 2017
A high level of extracellular matrix (ECM) turnover characterizes several lung diseases with fibrotic features. Type III collagen is one of the most abundant collagens in lung parenchyma, and cathepsins play a role in lung pathology, being responsible ...
Daniel Guldager Kring Rasmussen   +3 more
doaj   +1 more source

Complement, but Not Platelets, Plays a Pivotal Role in the Outcome of Mucormycosis In Vivo

open access: yesJournal of Fungi, 2023
Background: Mucormycetes, a heterogeneous group of fungi, induce a life-threatening disease called mucormycosis. Immune deficiencies represent a major risk factor; hence, we wanted to illuminate the role of complement and platelets in the defense against
Verena Harpf   +8 more
doaj   +1 more source

Complement activation in Hidradenitis suppurativa: Covert low-grade inflammation or innocent bystander?

open access: yesFrontiers in Immunology, 2022
Hidradenitis suppurativa (HS) is a chronic auto-inflammatory skin disease with a complex and multifactorial pathogenesis involving both the innate and adaptive immune system.
K. R. van Straalen   +8 more
doaj   +1 more source

Heliox versus trimix in closed‐circuit rebreather diving: A comparative study of pulmonary and decompression stress in male divers [PDF]

open access: yesPhysiol Rep
Abstract Closed‐circuit rebreather (CCR) and helium‐based breathing mixtures are widely used in technical diving. This study compared the effects of Heliox and Trimix on pulmonary function and decompression stress during CCR dives. Nineteen divers performed a standardized dive (50 ± 3 msw, 147 ± 10 min) using Heliox (16% O2/84% He; n = 9) or Trimix (16%
Gouin E   +9 more
europepmc   +2 more sources

The C-shaped root canal systems in mandibular second molars in an Emirati population

open access: yesScientific Reports, 2021
Our study aimed to describe the root and canal morphology of mandibular second molars in Emirati population and to study the prevalence and types of morphological change in C-shaped canal configuration along the root length in an effort to describe C ...
Summayah Khawaja   +6 more
doaj   +1 more source

Dysregulated biomarkers of innate and adaptive immunity predict infections and disease progression in cirrhosis

open access: yesJHEP Reports, 2023
Background & Aims: Cirrhosis-associated immune dysfunction (CAID) affects both innate and adaptive immunity. This study investigated the complement system, immunoglobulins, and acute-phase proteins and their prognostic relevance in patients with ...
Benedikt Simbrunner   +10 more
doaj   +1 more source

Utility of anti-immunoglobulin IgA, IgG, IgM, Kappa, Lambda - FITC (conjugate) cocktail in routine renal pathology practice

open access: yesSurgical and Experimental Pathology, 2023
Background Immunofluorescence studies on frozen sections are an essential component in the evaluation of renal biopsies. The basic panel in most centres constitutes IgG, IgA, IgM, C3c, C1q, Kappa and Lambda light chain antibody testing.
Shilpi Thakur, Balan Louis Gaspar
doaj   +1 more source

Overactivation of the complement system may be involved in intrarenal arteriolar lesions in IgA nephropathy

open access: yesFrontiers in Medicine, 2022
IntroductionIgA nephropathy (IgAN) encompasses a wide range of clinical and histology features. Some patients present without hematuria, with or without hypertension, still rapidly progress in renal function. Renal pathology of this part of patients were
Wei-yi Guo   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy