Results 21 to 30 of about 15,083 (218)

Complement levels and their diagnostic utility in neonatal sepsis [PDF]

open access: yesBMC Pediatrics
Background This study evaluated the diagnostic value of complement levels in neonatal sepsis and their roles in disease progression. Methods This diagnostic accuracy study, conducted in Guangdong Province, China (January 2021-February 2022), involved 41 ...
Fuqiang Diao   +7 more
doaj   +2 more sources

Complement in acute and chronic arthritides: assessment of C3c, C9, and protectin (CD59) in synovial membrane. [PDF]

open access: bronzeAnnals of the Rheumatic Diseases, 1996
Yrjö T. Konttinen   +7 more
exaly   +2 more sources

Complement alternative pathway activation in human nonalcoholic steatohepatitis. [PDF]

open access: yesPLoS ONE, 2014
The innate immune system plays a major role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Recently we reported complement activation in human NASH.
Filip M Segers   +9 more
doaj   +1 more source

Development of a Novel Enzyme-Linked Immunosorbent Assay Targeting a Neo-Epitope Generated by Cathepsin-Mediated Turnover of Type III Collagen and Its Application in Chronic Obstructive Pulmonary Disease. [PDF]

open access: yesPLoS ONE, 2017
A high level of extracellular matrix (ECM) turnover characterizes several lung diseases with fibrotic features. Type III collagen is one of the most abundant collagens in lung parenchyma, and cathepsins play a role in lung pathology, being responsible ...
Daniel Guldager Kring Rasmussen   +3 more
doaj   +1 more source

Complement in Renal Disease as a Potential Contributor to Arterial Hypertension

open access: yesKidney & Blood Pressure Research, 2021
Objective: Complement deposition is prevalent in kidney biopsies of patients with arterial hypertension and hypertensive nephropathy, but an association of hypertension and complement deposition or involvement of complement in the pathogenesis of ...
Lisa-Maren Fischer   +6 more
doaj   +1 more source

Complement, but Not Platelets, Plays a Pivotal Role in the Outcome of Mucormycosis In Vivo

open access: yesJournal of Fungi, 2023
Background: Mucormycetes, a heterogeneous group of fungi, induce a life-threatening disease called mucormycosis. Immune deficiencies represent a major risk factor; hence, we wanted to illuminate the role of complement and platelets in the defense against
Verena Harpf   +8 more
doaj   +1 more source

Complement activation in Hidradenitis suppurativa: Covert low-grade inflammation or innocent bystander?

open access: yesFrontiers in Immunology, 2022
Hidradenitis suppurativa (HS) is a chronic auto-inflammatory skin disease with a complex and multifactorial pathogenesis involving both the innate and adaptive immune system.
K. R. van Straalen   +8 more
doaj   +1 more source

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