Haemolytic complement activity and C3c serum concentration in pigs [PDF]
Archives Animal Breeding, 1999 Abstract. Because of the importance of the complement system in disease resistance through direct lysis of target cells and support of other mechanisms of the immune System, individual Variation in haemolytic complement activity and C3 concentration in pigs prior and after vaccination were evaluated.
Wimmer, K. +6 more
openaire +3 more sources
Intrathecal synthesis of complement components C3c and C4 in the central nervous system infections with signs of the acute serous meningitis syndrome [PDF]
Vojnosanitetski Pregled, 2002 Two hundred and ten patients with meningismus and the infections of the central nervous system (CNS) with the clinical symptoms and signs of the acute serous meningitis syndrome, were divided into groups according to etiology (enterovirus meningitis ...
Tatomirović Željka +2 more
doaj +3 more sources
Classical pathway activity C3c, C4 and C1-inhibitor protein reference intervals determination in EDTA plasma [PDF]
Biochemia Medica, 2019 Introduction Reference intervals (RIs) for complement assays in EDTA plasma samples have not previously been published. The objectives of the present study were to validate and/or determine RIs for classical pathway (CP50) activity and C3c, C4 and C1 ...
B. Lopez +12 more
semanticscholar +2 more sources
Complement alternative pathway activation in human nonalcoholic steatohepatitis. [PDF]
PLoS ONE, 2014 The innate immune system plays a major role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Recently we reported complement activation in human NASH.
Filip M Segers +9 more
doaj +2 more sources
Expression of melanoma differentiation-associated gene 5 in the epidermis and cutaneous deposition of complement C3 and immunoglobulins in patients with dermatomyositis. [PDF]
PLoS ONEObjectivesDermatomyositis (DM) is an autoimmune disease characterized by interface dermatitis, but the immunopathological features underlying cutaneous inflammation remain incompletely understood.
Yoshiaki Zaizen +6 more
doaj +2 more sources
Redefined complement C3c structures have significant increase in the plasma of ovarian cancer patients. [PDF]
J Chin Med AssocBackground: Ovarian cancer (OC) is the third most common gynecological cancer. Effective biomarkers are required for OC as in the case of other cancers.
Chen DH +4 more
europepmc +2 more sources
Reibergrama para la evaluación de la síntesis intratecal de C3c
Arquivos de Neuro-Psiquiatria, 2006 INTRODUCCIÓN: El diagrama de las razones de Reiber o reibergrama cobra cada día mayores usos para la caracterización de la síntesis intratecal de proteínas.
Dorta-Contreras Alberto Juan +6 more
doaj +1 more source
Selective Complement Inhibition in Anti-p200 Pemphigoid: Immune Infiltrate Profiles and Therapeutic Implications Compared to Bullous Pemphigoid [PDF]
BiomoleculesAnti-p200 pemphigoid is an autoimmune blistering disease (AIBD) caused by autoantibodies against laminin β4 and/or γ1, and clinically resembles bullous pemphigoid (BP) as well as the inflammatory variant of epidermolysis bullosa acquisita (EBA).
Shirin Emtenani +5 more
doaj +2 more sources
Complement and autoantibody levels under anifrolumab therapy in SLE: implications for clinical practice [PDF]
Frontiers in ImmunologyIntroductionAnifrolumab (ANI), a type I interferon receptor antagonist, has demonstrated clinical efficacy in systemic lupus erythematosus (SLE). However, its effects on serological markers commonly used to assess disease activity in clinical practice ...
Jan-Gerd Rademacher +3 more
doaj +2 more sources
Structure of Compstatin in Complex with Complement Component C3c Reveals a New Mechanism of Complement Inhibition* [PDF]
Journal of Biological Chemistry, 2007 Undesired complement activation is a major cause of tissue injury in various pathological conditions and contributes to several immune complex diseases. Compstatin, a 13-residue peptide, is an effective inhibitor of the activation of complement component
B. Janssen +3 more
semanticscholar +2 more sources