Results 11 to 20 of about 6,868 (161)

Glomerular C4d deposition in proliferative glomerular diseases

Indian Journal of Pathology and Microbiology, 2021
Introduction: The aim of this study was to evaluate the immunohistochemical expression of C4d in native renal biopsies of proliferative glomerular diseases, complement pathways in these diseases, and assess the relationship of C4d with histological and ...
Sarojini Raman, Pallavi Mishra, Ansuman Panigrahi, Nikunj K Rout, Kanakalata Dash   +4 more
doaj   +3 more sources

C4d expression in focal segmental glomerulosclerosis

Nefrología (English Edition)
Background: There is a little information about of expression of C4d (complement fragment) in Focal segmental glomerulosclerosis (FSGS) subtypes. Our aim was to determine the expression of C4d in FSGS subtypes in percutaneous native renal biopsies in a ...
Venice Chávez Valencia, Victoriano Pérez-Vázquez, Anel Gómez García, Katya Vargas-Ortiz, Martha Arisbeth Villanueva Pérez, Marisol Godínez Rubí, Leonardo Pazarín Villaseñor, Sergio Gutiérrez Castellanos, Citlalli Orizaga de la Cruz   +8 more
doaj   +3 more sources

Complement Hyperactivation Is Mediated by Alternative and Lectin Pathways During Early Phase of Severe Vaccination-Omicron BA.5 Infection. [PDF]

J Med Virol
ABSTRACT Complement temporal activation kinetics, activation pathways, and their relationship with thromboinflammation and antibody responses in severe vaccination‐COVID‐19 remains unclear. Based on a vaccinated‐infected cohort, we analyzed complement immune responses across mild to critical COVID‐19 cases by a dynamic model.
Cao J, Yang G, Cui T, Qin J, Huang D, Jin S, Yang X, Huang M, Su X, Liu S, Xia Y, Deng S, Luo C, Zhao Z, Zhang Y, Zhong N, Wang Z.   +16 more
europepmc   +2 more sources

Arteriolar C4d in IgA Nephropathy: A Cohort Study [PDF]

American Journal of Kidney Diseases, 2020
Glomerular C4d (C4dG) as an indicator of the lectin pathway of complement activation in immunoglobulin A nephropathy (IgAN) has been associated with more severe kidney damage. Recent studies have suggested that vascular lesions in IgAN biopsy specimens with complement deposition are also associated with disease progression.
Faria, B., Canao, P., Cai, Q.Q., Henriques, C., Matos, A.C., Poppelaars, F., Costa, M.G. da, Daha, M.R., Silva, R., Pestana, M., Seelen, M.A.   +10 more
openaire   +3 more sources

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

CERIF for datasets (C4D) [PDF]

, 2014
The overall aim of CERIF for Datasets (C4D) is to develop a framework for incorporating metadata into CERIF (the Common European Research Information Format) such that research organisations and researchers can better discover and make use of existing and future research datasets, wherever they may be held. CERIF provides a standardised way of managing
Brander, Scott, Clements, Anna, McCutcheon, Valerie, Cranner, Paul, Henderson, Ryan, Ginty, Kevin   +5 more
openaire   +3 more sources

Clinical and pathological correlations of C4d immunostaining and its infl uence on the outcome of kidney transplant recipients

Brazilian Journal of Nephrology, 2011
INTRODUCTION: C4d is a marker of antibody-mediated rejection (ABMR) in kidney allografts, although cellular rejection also have C4d deposits. OBJECTIVE: To correlate C4d expression with clinico-pathological parameters and graft outcomes at three years ...
Virna Nowotny Carpio, Carolina Rech, Evlyn Isabel Eickhoff, Karla Laís Pegas, Maria Isabel Albano Edelweiss, Luiz Felipe Santos Gonçalves, Roberto Ceratti Manfro, Francisco Veríssimo Veronese   +7 more
doaj   +1 more source

C4d immunohistochemistry in membranous nephropathy

Journal of Laboratory Physicians, 2014
ABSTRACT Background: Membranous nephropathy (MN) is the most common cause of nephropathy in adults. The diagnosis is based on characteristic light microscopic, electron microscope and immunofluorescence (IF) findings. In early MN, the light microscopic findings may be difficult to differentiate from minimal chain disease.
Hui, Monalisa, Uppin, Megha S, Prayaga, Aruna K, Raju, Sree Bhushan, Rajasekhar, Liza   +4 more
openaire   +2 more sources

C4d/CD34 double-immunofluorescence staining of renal allograft biopsies for assessing peritubular capillary C4d positivity [PDF]

Modern Pathology, 2012
Immunofluorescence detection of the complement split product C4d along peritubular capillaries in renal allograft biopsies is the mainstay for the diagnosis of antibody-mediated rejection. The extent of peritubular capillary C4d positivity may have significant clinical ramifications; however, peritubular capillary density in the renal cortex is often ...
Kuang-Yu, Jen, Thuy B, Nguyen, Flavio G, Vincenti, Zoltan G, Laszik   +3 more
openaire   +2 more sources