Results 71 to 80 of about 6,868 (161)
The insider's perspective: The intracellular complosome and immune cell dynamics in cancer
Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.Intracellular complement (complosome) shapes the tumour immune microenvironment. Complosome's role in cancer is underrecognised yet central to tumour immunity. C3/C5‐driven complosome signals rewire T‐cell activation, fate and metabolism. Complosome activity can promote pro‐tumour immune cell function.
Alexandra Bennion +2 more
wiley +1 more source
C4d-negative antibody-mediated rejection: A pathologist's perspective and clinical outcome
Saudi Journal of Kidney Diseases and Transplantation, 2018 Banff'13 update included C4d-antibody-mediated rejection (ABMR) as a separate entity responsible for graft dysfunction with limited clinical/prognostic implications.
Lovelesh Kumar Nigam +5 more
doaj +1 more source
Peritubular Capillary C4d Deposition in Chronic Allograft Dysfunction
Yonsei Medical Journal, 2004 Peritubular capillary (PTC) C4d staining represents a marker for acute humoral rejection, however, the impact of positive staining on chronic allograft dysfunction has received little attention. Ninety-three renal allograft biopsies from 93 patients were selected from a total of 174 renal allograft biopsies, which were obtained 6 months or more after ...
Hyeon Joo, Jeong +5 more
openaire +3 more sources
Nordicom Review, 2020 The complexity of development and social change and growing tensions between dominant results-based and emerging learning and improvement-based approaches to evaluating development interventions have created major challenges for the evaluation of ...
Lennie June, Tacchi Jo
doaj +1 more source
PLoS ONE, 2015 Molecular markers in bronchial fluids may contribute to the diagnosis of lung cancer. We previously observed a significant increase of C4d-containing complement degradation fragments in bronchoalveolar lavage (BAL) supernatants from lung cancer patients ...
Daniel Ajona +13 more
doaj +1 more source
Epidemiology and Pathophysiology of Glomerular C4d Staining in Native Kidney Biopsies
Kidney International Reports, 2019 Introduction: Routine C4d staining in renal transplantation has stimulated its use in kidney biopsies with glomerulonephritis (GN). Methodical description on staining patterns in the native kidney is not available.
Cinthia B. Drachenberg +6 more
doaj +1 more source
Advanced Biomedical Research, 2012 Background: C4d as a part of complement activation process is a marker for detecting antibody-mediated rejection (ABMR) and its positivity accompanied by positive donor specific antibody (DSA), and morphologic view of humoral rejection has been suggested
Diana Taheri +8 more
doaj +1 more source
C4d Staining in the Diagnosis of C3 Glomerulopathy [PDF]
Journal of the American Society of Nephrology, 2015 In 2010 we suggested the term C3 glomerulopathy for glomerular disease in which there was isolated deposition of C3 in glomeruli in the absence of immunoglobulins and of components of the classic pathway of complement activation.[1][1] The presence of such isolated C3 implies that complement ...
openaire +2 more sources
C4d at Crossroads Between Post-Infectious Glomerulonephritis and C3 Glomerulopathy
International Journal of Nephrology and Renovascular Disease, 2021 Shaarif Bashir,1 Mudassar Hussain,1 Aurangzeb Afzal,2 Usman Hassan,1 Maryam Hameed,1 Sajid Mushtaq1 1Department of Pathology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, 54000, Pakistan; 2Department of Nephrology, Lahore General ...
Bashir S +5 more
doaj