Results 121 to 130 of about 795,908 (273)
One‐Step Glycoengineering of NK Cells With High‐Affinity Siglec Ligands for Cancer Immunotherapy
Advanced Science, EarlyView.This study develops an engineered NmCSS enzyme with improved activity for bulky group modified sialic acids, enabling efficient synthesis of structurally diverse sialoside analogs in a single step. Glycan microarray screening identified Siglec high‐affinity ligands, which were incorporated onto natural killer (NK) cells via a one‐pot enzymatic system ...
Shuai Hu +8 more
wiley +1 more source
Beyond the Non‐Hermitian Skin Effect: Scaling‐Controlled Topology from Exceptional‐Bound Bands
Advanced Science, EarlyView.ABSTRACT We establish a novel mechanism for topological transitions in non‐Hermitian systems that are controlled by the system size. Based on a new paradigm known as exceptional‐bound (EB) band engineering, its mechanism hinges on the unique critical scaling behavior near an exceptional point, totally unrelated to the well‐known non‐Hermitian skin ...
Mengjie Yang, Ching Hua Lee
wiley +1 more source
Advanced Science, EarlyView.It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan +13 more
wiley +1 more source
GIS w polskiej edukacji wyższej – dyskusja [PDF]
, 2015 Norvay Grants FSS/2014/HEI/W/0114/U ...
Jażdżewska, Iwona
core
Advanced Science, EarlyView.Difluoromethyl (CF2H) group, the bioisostere of hydroxyl thiol methyl or amide is privileged in medicinal chemistry due to hydrogen‐binding ability and lipophilic, metabolically stable, and chemical inert nature. However, enatioseleceive CF2H introduction remains challenging.
Peng Liu +9 more
wiley +1 more source
Teachers’ emotional intelligence — a vital component in the learning process Nina Barłożek [PDF]
, 2013 Teachers’ role in education requires many various abilities. One of such fundamental capacities in the contemporary world is emotional intelligence. Emotional aspects in the teaching process influence overall student performance, which has been proved in
Barłożek, Nina
core
Advanced Science, EarlyView.This study elucidates how steric hindrance in amines creates a dual effect in CO2 capture: it thermodynamically favors the reaction by shifting the pathway from carbamate to alkyl carbonate formation, increasing capacity and lowering regeneration heat, while simultaneously slightly slowing the kinetics.
Xiaoyi Gao +8 more
wiley +1 more source
Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy
Advanced Science, EarlyView.Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao +12 more
wiley +1 more source