Results 131 to 140 of about 4,589 (165)
Some of the next articles are maybe not open access.
Stereoselective Synthesis of the C31−C40/C43−C52 Unit of Amphidinol 3
The Journal of Organic Chemistry, 2009A concise synthesis of a tetrahydropyran ring system corresponding to the C31-C40 and C43-C52 units of amphidinol 3 is described. Successive chemoselective reactions, i.e., cross-metathesis to differentiate the iodoolefin from the terminal olefin and Sharpless asymmetric dihydroxylation on the resulting E-olefin, resulted in expeditious synthesis of an
Mitsunori, Kanemoto +2 more
openaire +2 more sources
Abstract C52: Induction of homologous recombination by DNA nicks
Cancer Research, 2013Abstract Homologous recombination (HR) is a major mechanism of DNA repair, such that mutations in HR genes are associated with tumor susceptibility. We have used a recently adapted system for genome engineering to study HR mechanisms in mammalian cells.
Lianne E.M. Vriend +2 more
openaire +1 more source
Abstract C52: Collagen-mediated chromatin remodeling promotes chemoresistance in pancreatic cancer
Cancer Research, 2011Abstract Pancreatic ductal adenocarcinoma (PDAC), the fourth leading cause of cancer-related deaths in the U.S., is associated with a pronounced collagenrich stromal reaction that has been shown to contribute to chemoresistance. We recently published that PDAC cells grown in the collagen microenvironment are resistant to gemcitabine ...
Surabhi Y. Danqi-Garimella +1 more
openaire +1 more source
Development of an Access Route to the C31−C52 Central Core of Amphidinol 3
Organic Letters, 2007[reaction: see text] An asymmetric synthesis of the heavily oxygenated inner sector of amphidinol 3 constituted of C31-C52 is described. The successful pathway highlights construction of the pair of identical tetrahydropyran subunits from a common intermediate.
Matthew W, Bedore +2 more
openaire +2 more sources
The Journal of Chemical Physics, 2007
The 437 classical isomers of fullerene C52 have been studied by PM3, HCTH/3-21G, and B3LYP∕6-31G(d). C2:029 with the least number of adjacent pentagons is predicted to be the most stable isomer. The investigations show that both the number of adjacent pentagons and the degree of aromaticity play important roles in the relative stabilities of fullerene ...
De-Li, Chen +3 more
openaire +2 more sources
The 437 classical isomers of fullerene C52 have been studied by PM3, HCTH/3-21G, and B3LYP∕6-31G(d). C2:029 with the least number of adjacent pentagons is predicted to be the most stable isomer. The investigations show that both the number of adjacent pentagons and the degree of aromaticity play important roles in the relative stabilities of fullerene ...
De-Li, Chen +3 more
openaire +2 more sources
An improved synthesis of the C42–C52 segment of ciguatoxin 3C
Tetrahedron Letters, 2018Abstract In our previously reported method for the construction of the IJKLM-ring of ciguatoxin 3C (CTX3C), the lengthy synthetic process for the intermediate C42–C52 (L-ring) segment was problematic. Therefore, a new and improved procedure for the C42–C52 segment, having modified protecting groups, was developed.
Takafumi Saito +8 more
openaire +1 more source
Abstract C52: A novel combinatorial treatment for glioblastoma of temozolomide and JLK1486.
Molecular Cancer Therapeutics, 2013Abstract Background: Glioblastoma multiforme (GBM) is a grade IV brain tumor characterized by a heterogeneous population of cells that are highly invasive and resistant to chemotherapeutic treatments. The current standard of care, comprised of surgical resection followed by radiation and chemotherapy, only provides GBM patients with a 12-
Jessica L. Weatherbee +3 more
openaire +1 more source
European Heart Journal Supplements, 2023
Abstract Introduction Ventricular fibrillation (VF) Amplitude Spectral Area (AMSA) is a well–established predictor of successful defibrillation and return of spontaneous circulation (ROSC). Attending to the limited evidence on the topic, gender seems to affect AMSA, and higher values have been ...
L Vicini Scajola +13 more
openaire +1 more source
Abstract Introduction Ventricular fibrillation (VF) Amplitude Spectral Area (AMSA) is a well–established predictor of successful defibrillation and return of spontaneous circulation (ROSC). Attending to the limited evidence on the topic, gender seems to affect AMSA, and higher values have been ...
L Vicini Scajola +13 more
openaire +1 more source
Abstract C52: Gene silencing of c-met leads to brain metastasis inhibitory effects
Cancer Research, 2013Abstract An unfortunate consequence of improvements in the treatments of advanced primary cancers is the concurrent increase of metastatic brain tumors. Despite of unfavorable clinical prognosis, radiation therapy is still the only viable treatment option for brain metastases.
Se Jeong Lee +5 more
openaire +1 more source
Cancer Epidemiology, Biomarkers & Prevention, 2014
Abstract Background: The limited research of breast cancer screening among different American Muslim groups consistently demonstrates low rates of mammography. There has been no survey of how religion-related factors influence screening patterns in a diverse sample of American Muslims.
Aasim I. Padela +6 more
openaire +1 more source
Abstract Background: The limited research of breast cancer screening among different American Muslim groups consistently demonstrates low rates of mammography. There has been no survey of how religion-related factors influence screening patterns in a diverse sample of American Muslims.
Aasim I. Padela +6 more
openaire +1 more source