Results 171 to 180 of about 192,611 (304)

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Endothelin-3 and T-type Ca<sup>2+</sup> channels drive enteric neural crest cell calcium activity, contractility and migration. [PDF]

open access: yesNat Commun
Chevalier NR   +10 more
europepmc   +1 more source

L- and T-type Ca2+ channels dichotomously contribute to retinal ganglion cell injury in experimental glaucoma. [PDF]

open access: yesNeural Regen Res, 2023
Wang HN   +7 more
europepmc   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

open access: yesAdvanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib   +8 more
wiley   +1 more source

Gating of hair cell Ca<sup>2+</sup> channels governs the activity of cochlear neurons. [PDF]

open access: yesSci Adv
Karagulyan N   +11 more
europepmc   +1 more source

T-Type Ca2+ Channels Boost Neurotransmission in Mammalian Cone Photoreceptors. [PDF]

open access: yesJ Neurosci, 2022
Davison A   +3 more
europepmc   +1 more source

Non‐Equilibrium Synthesis of Whitlockite Assisted by Localized H2O Vapor Pressure

open access: yesAdvanced Science, EarlyView.
A carbon substrate acts as a microheater during intense pulsed light irradiation, enabling rapid heating and cooling for whitlockite formation. In contrast to conventional white ceramic synthesis with weak photothermal response, this platform concentrates thermal energy locally and promotes phase‐selective crystallization under ultrafast ...
Min‐Jung Kim   +5 more
wiley   +1 more source

Ca2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons. [PDF]

open access: yesSci Adv, 2022
Zampese E   +14 more
europepmc   +1 more source

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