Results 61 to 70 of about 31,767 (201)

Continuously Tunable Ca2+ Regulation of RNA-Edited CaV1.3 Channels

Cell Reports, 2013
CaV1.3 ion channels are dominant Ca2+ portals into pacemaking neurons, residing at the epicenter of brain rhythmicity and neurodegeneration. Negative Ca2+ feedback regulation of CaV1.3 channels (CDI) is therefore critical for Ca2+ homeostasis ...
Hojjat Bazzazi, Manu Ben Johny, Paul J. Adams, Tuck Wah Soong, David T. Yue   +4 more
doaj   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Ca2+ channels, ca2+ sparks, and regulation of arterial smooth muscle function

, 2000
In cardiac, skeletal, and arterial muscle, transient, spatially localized elevations in [Ca2+](i), termed 'Ca2+ sparks', have been observed using confocal laser scanning microscopy.
Gollasch, M., Nelson, M. T.; id_orcid, Löhn, M., Fürstenau, M., Luft, F. C., Haller, H.   +5 more
core   +7 more sources

Generation and Role of Oscillatory Contractions in Mouse Airway Smooth Muscle

Cellular Physiology and Biochemistry, 2018
Background/Aims: Tetraethylammonium chloride (TEA) induces oscillatory contractions in mouse airway smooth muscle (ASM); however, the generation and maintenance of oscillatory contractions and their role in ASM are unclear.
Hao Xu, Ping Zhao, Wen-Jing Zhang, Jun-Ying Qiu, Li Tan, Xiao-Cao Liu, Qian Wang, Xi Luo, Yu-Shan She, Dun-An Zang, Bei-Bei Liu, Lei Cao, Xiao-Xue Zhao, Yuan-Yuan Chen, Meng-Yue Li, Jinhua Shen, Yong-Bo Peng, Lu Xue, Meng-Fei Yu, Weiwei Chen, Li-Qun Ma, Gangjian Qin, Qing-Hua Liu   +22 more
doaj   +1 more source

Control of Ca2+ Influx and Calmodulin Activation by SK-Channels in Dendritic Spines. [PDF]

PLoS Computational Biology, 2016
The key trigger for Hebbian synaptic plasticity is influx of Ca2+ into postsynaptic dendritic spines. The magnitude of [Ca2+] increase caused by NMDA-receptor (NMDAR) and voltage-gated Ca2+ -channel (VGCC) activation is thought to determine both the ...
Thom Griffith, Krasimira Tsaneva-Atanasova, Jack R Mellor   +2 more
doaj   +1 more source

Fabrication Routes for Ionic Conducting Fiber Strain Sensors

Advanced Engineering Materials, EarlyView.
Ionic conducting fiber strain sensors (ICFSs) offer compliant, textile‐integrable sensing. Thus far, the commercialization of ICFSs has been constrained by fiber fabrication routes. This review provides a fabrication‐centric analysis of ICFSs correlating processing strategies with material properties and scalability.
Leo John Kershaw, Zhanhong Yang, Anne Ladegaard Skov, Magdalena Skowyra   +3 more
wiley   +1 more source

T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites.

, 2008
International audienceT-type Ca2+ channels (T channels) underlie rhythmic burst discharges during neuronal oscillations that are typical during sleep. However, the Ca2+-dependent effectors that are selectively regulated by T currents remain unknown.
John P Adelman, Lucius Cueni, Canepari, M., Franken, P., Cueni, Lucius, Canepari, Marco, Lüthi, Anita, Luján, Rafael, Adelman, John P, Watanabe, M., Adelman, J.P., Cueni, L., Emmenegger, Yann, Emmenegger, Y., Marco Canepari, Paul Franken, Lüthi, A., Rafael Luján, Bond, Chris T, Watanabe, Masahiko, Masahiko Watanabe, Chris T Bond, Franken, Paul, Anita Lüthi, Luján, R., Yann Emmenegger, Bond, C.T., Franken P, Bond CT, Cueni L, Adelman JP, Lüthi A, Watanabe M, Canepari M, Emmenegger Y, Luján R   +35 more
core   +1 more source

Bio‐Inspired Synthesis of Macroporous Single Crystal Particles as Scattering Agents

Advanced Functional Materials, EarlyView.
A general strategy is presented that delivers unique, single‐crystal microparticles that combine submicron macroporosity and uniform particle shapes. A bioinspired approach is used to occlude three distinct types of additives – polystyrene microspheres, polymer vesicles and amino acids – within calcite single crystals, and subsequent thermal annealing ...
Stephanie E. Foster, Gianni Jacucci, Ouassef Nahi, Thomas Kress, Zabeada Aslam, Stuart Micklethwaite, Alexander N. Kulak, Rik Drummond‐Brydson, Melinda J. Duer, Yi‐Yeoun Kim, Silvia Vignolini, Fiona C. Meldrum   +11 more
wiley   +1 more source

Pathophysiological Significance of T-type Ca2+ Channels: Role of T-type Ca2+ Channels in Renal Microcirculation

Journal of Pharmacological Sciences, 2005
Since conventional Ca2+ antagonists, with predominant blockade of L-type voltage-dependent Ca2+ channels, elicit preferential dilation of afferent arterioles, they might ostensibly aggravate glomerular hypertension. Recently, novel Ca2+ antagonists, with
Koichi Hayashi, Shu Wakino, Koichiro Homma, Naoki Sugano, Takao Saruta   +4 more
doaj   +1 more source

Ca2+ regulation of TRP ion channels [PDF]

, 2018
Ca2+ signaling influences nearly every aspect of cellular life. Transient receptor potential (TRP) ion channels have emerged as cellular sensors for thermal, chemical and mechanical stimuli and are major contributors to Ca2+ signaling, playing an ...
Hasan, Raquibul, Zhang, Xuming, Raquibul Hasan, Xuming Zhang   +3 more
core   +1 more source