Results 61 to 70 of about 300,385 (307)
Control of Ca2+ Influx and Calmodulin Activation by SK-Channels in Dendritic Spines. [PDF]
PLoS Computational Biology, 2016 The key trigger for Hebbian synaptic plasticity is influx of Ca2+ into postsynaptic dendritic spines. The magnitude of [Ca2+] increase caused by NMDA-receptor (NMDAR) and voltage-gated Ca2+ -channel (VGCC) activation is thought to determine both the ...
Thom Griffith +2 more
doaj +1 more source
Protection Against Cardiac Injury by Small Ca\u3csup\u3e2 +\u3c/sup\u3e-Sensitive K\u3csup\u3e+\u3c/sup\u3e Channels Identified in Guinea Pig Cardiac Inner Mitochondrial Membrane [PDF]
, 2013 We tested if small conductance, Ca2 +‐sensitive K+ channels (SKCa) precondition hearts against ischemia reperfusion (IR) injury by improving mitochondrial (m) bioenergetics, if O2‐derived free radicals are required to initiate protection via SKCa ...
Aldakkak, Mohammed +9 more
core +1 more source
Interaction of Ladle Slag With Varying SiO2 Content and Recyclate‐Based MgO–C Refractories
Advanced Engineering Materials, EarlyView.Ladle slags (CaO/Al2O3 = 1) with 1–20 wt% SiO2 were investigated in contact with industrial MgO–C refractories fabricated from fresh magnesia and 50 wt% recyclate. The sessile drop method at 1600°C reveals intensive gas formation, delayed slag infiltration in recyclate‐based samples, and, under high‐SiO2 slag, formation of a dense MgAl2O4‐rich ...
Anton Yehorov +6 more
wiley +1 more source
PIP2 alters Ca2+ currents in acutely dissociated supraoptic oxytocin neurons
Physiological Reports, 2019 Magnocellular neurosecretory cells (MNCs) occupying the supraoptic nucleus (SON) contain voltage‐gated Ca2+ channels that provide Ca2+ for triggering vesicle release, initiating signaling pathways, and activating channels, such as the potassium channels ...
Matthew K. Kirchner +4 more
doaj +1 more source
Continuously Tunable Ca2+ Regulation of RNA-Edited CaV1.3 Channels
Cell Reports, 2013 CaV1.3 ion channels are dominant Ca2+ portals into pacemaking neurons, residing at the epicenter of brain rhythmicity and neurodegeneration. Negative Ca2+ feedback regulation of CaV1.3 channels (CDI) is therefore critical for Ca2+ homeostasis ...
Hojjat Bazzazi +4 more
doaj +1 more source
TRPC5 Is a Ca2+-activated Channel Functionally Coupled to Ca2+-selective Ion Channels [PDF]
Journal of Biological Chemistry, 2009 TRPC5 forms non-selective cation channels. Here we studied the role of internal Ca(2+) in the activation of murine TRPC5 heterologously expressed in human embryonic kidney cells. Cell dialysis with various Ca(2+) concentrations (Ca(2+)(i)) revealed a dose-dependent activation of TRPC5 channels by internal Ca(2+) with EC(50) of 635.1 and 358.2 nm at ...
Stefan Alfred, Gross +6 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This review systematically highlights the latest achievements in mixed‐valence states relevant to hydrogen and oxygen evolution reactions, providing essential insights into future directions and methods for large‐scale practical implementation. This critical review is expected to provide an overview of recent advancements in diverse valence‐state metal
Jitendra N. Tiwari +4 more
wiley +1 more source
Generation and Role of Oscillatory Contractions in Mouse Airway Smooth Muscle
Cellular Physiology and Biochemistry, 2018 Background/Aims: Tetraethylammonium chloride (TEA) induces oscillatory contractions in mouse airway smooth muscle (ASM); however, the generation and maintenance of oscillatory contractions and their role in ASM are unclear.
Hao Xu +22 more
doaj +1 more source
High-Voltage Activated Ca2+ Channel [PDF]
, 1993 Calcium channels are part of the signal system which is vital for intercellular communication in higher multicellular organisms. They transduce electrical or hormonal signals into a chemical second messenger, namely calcium. The cytosolic calcium concentration controls numerous cellular functions by binding to distinct calcium receptor binding proteins
Hofmann, Franz +6 more
openaire +2 more sources