Results 251 to 260 of about 202,389 (291)

Profilin is required for Ca2+ homeostasis and Ca2+-modulated bud formation in yeast

Molecular Genetics and Genomics, 2013
A cls5-1 mutant of Saccharomyces cerevisiae is specifically sensitive to high concentrations of Ca2+, with elevated intracellular calcium content and altered cell morphology in the presence of 100 mM Ca2+. To reveal the mechanisms of the Ca2+-sensitive phenotype, we investigated the gene responsible and its interacting network.
Mitsunori, Yoshida, Shinsuke, Ohnuki, Yoko, Yashiroda, Yoshikazu, Ohya   +3 more
openaire   +2 more sources

The Mitochondrial Na+/Ca2+ Exchanger is Necessary but Not Sufficient for Ca2+ Homeostasis and Viability

2018
Luongo et al. found that the mitochondrial Na+/Ca2+ exchanger (NCLX) was essential for Ca2+ homeostasis and viability. Here, we re-analyze their data in terms of fractal self-similarity and quantitative difference (QD). We calculated the 7-dimension data from NCLX conditional loss-of-function mouse models, and the 9-dimension data from NCLX ...
Timon Cheng-Yi, Liu, Xiao-Ming, Tang, Rui, Duan, Lei, Ma, Ling, Zhu, Quan-Guang, Zhang   +5 more
openaire   +2 more sources

[Ca2+ homeostasis in mammalian cells].

Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1994
The cytoplasmic free calcium concentration ([Ca2+]i) is one of the most important factors in the regulation of the cellular activity. We therefore studied in this work the changes of [Ca2+]i during muscle excitation with optical techniques in intact smooth muscle preparations.
B, Himpens, L, Missiaen
openaire   +1 more source

Maintenance of Ca2+ Homeostasis in the Myocardium

1984
Maintenance of intracellular homeostasis with respect to Ca++ during prolonged episodes of ischaemia and upon reperfusion is critical to the survival of the myocardium. Loss of Ca++ homeostasis results in massive ultrastructural damage, associated with excessive phospholipase and proteinase activation.
openaire   +1 more source

Ca2+ Homeostasis in Human Platelets

1997
Ca2+ is an agent of universal significance that plays a key role in triggering many platelet functions. The understanding of its regulation is paramount to our appreciation of the mechanisms of platelet activation. The complete activation by all of the platelet agonists involves elevation of the cytosolic levels of Ca2+.
openaire   +1 more source

Intracellular Ca2+ Homeostasis: Receptor-Activated Ca2+ Channels and Intracellular Ca2+ Pools

1991
In eukaryotic cells, the intracellular free calcium concentration, [Ca2+]i, plays a critical role at almost every level. Key functions, such as excitability, contraction, metabolism and gene expression require changes in [Ca2+]i.
C. Fasolato, M. Zottini, P. Chiozzi, S. Treves, A. Villa, E. Clementi, J. Meldolesi, T. Pozzan   +7 more
openaire   +1 more source

Ca2+ homeostasis and cancer

Cell Calcium, 2019
Mathieu, Gautier, Mohamed, Trebak, Andrea, Fleig, Christophe, Vandier, Halima, Ouadid-Ahidouch   +4 more
openaire   +2 more sources

Disturbed Ca2+ Homeostasis in Muscle-Wasting Disorders

2018
Ca2+ is essential for proper structure and function of skeletal muscle. It not only activates contraction and force development but also participates in multiple signaling pathways. Low levels of Ca2+ restrain muscle regeneration by limiting the fusion of satellite cells.
openaire   +2 more sources

Rapidly exchanging Ca2+ stores: Role in the control of Ca2+ homeostasis and [Ca2+] in oscillations

Neurophysiology, 1995
The rapidly exchanging intracellular calcium stores play an important role in control of cytoplasmic calcium homeostasis and in generation of intracellular calcium signals. These stores are specific intracellular compartments which are able to accumulate and release calcium in response to appropriate stimuli. Two types of stores can be distinguished in
openaire   +1 more source

Ca2+ Homeostasis in Normal and Diseased Heart

Interventional Cardiology Journal, 2016
The heart’s ability to contract greatly depends on a mechanism termed excitation-contraction coupling (E-C coupling). In each heartbeat, the open of voltage gated L-type Ca2+ channel (LTCC) due to membrane depolarization results in the influx of a small amount of Ca2+, which in turn triggers massive Ca2+ release from sarcoplasmic reticulum (SR).
openaire   +1 more source