Results 11 to 20 of about 31,790 (211)
Ca2+ Signaling in B Cells [PDF]
The Scientific World Journal, 2010 An increase in intracellular Ca2+ concentration is one of the major initial steps in B-cell activation that occurs within minutes after antigen receptor (BCR) engagement.
Taras Lyubchenko
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Nanotechnology‐Fortified Manipulation of Cell Ca2+ Signaling
Small ScienceThe manipulation of cytosolic Ca2+ concentration ([Ca2+]i) plays a crucial role in the study of Ca2+ signaling and the therapy of its affected diseases.
Yaofeng Zhou +6 more
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Ca2+ Signaling in Cardiac Fibroblasts and Fibrosis-Associated Heart Diseases
Journal of Cardiovascular Development and Disease, 2019 Cardiac fibrosis is the excessive deposition of extracellular matrix proteins by cardiac fibroblasts and myofibroblasts, and is a hallmark feature of most heart diseases, including arrhythmia, hypertrophy, and heart failure.
Jianlin Feng +5 more
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IP3 Receptors, Mitochondria, and Ca2+ Signaling: Implications for Aging [PDF]
Journal of Aging Research, 2011 The tight interplay between endoplasmic-reticulum-(ER-) and mitochondria-mediated Ca2+ signaling is a key determinant of cellular health and cellular fate through the control of apoptosis and autophagy.
Jean-Paul Decuypere +5 more
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Shigella IpaA mediates actin bundling through diffusible vinculin oligomers with activation imprint
Cell Reports, 2023 Summary: Upon activation, vinculin reinforces cytoskeletal anchorage during cell adhesion. Activating ligands classically disrupt intramolecular interactions between the vinculin head and tail domains that bind to actin filaments.
Cesar Valencia-Gallardo +17 more
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The carboxy terminal coiled-coil modulates Orai1 internalization during meiosis
Scientific Reports, 2021 Regulation of Ca2+ signaling is critical for the progression of cell division, especially during meiosis to prepare the egg for fertilization. The primary Ca2+ influx pathway in oocytes is Store-Operated Ca2+ Entry (SOCE).
Rawad Hodeify +9 more
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Experimental and Molecular Medicine, 2023 Hepatic glucose production by glucagon is crucial for glucose homeostasis during fasting, yet the underlying mechanisms remain incompletely delineated. Although CD38 has been detected in the nucleus, its function in this compartment is unknown.
So-Young Rah +6 more
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The Physiopathologic Roles of Calcium Signaling in Podocytes
Frontiers in Bioscience-Landmark, 2023 Calcium (Ca2+) plays a critical role in podocyte function. The Ca2+-sensitive receptors on the cell surface can sense changes in Ca2+ concentration, and Ca2+ flow into podocytes, after activation of Ca2+ channels (such as transient receptor potential ...
Yu-Chi Tu +6 more
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PLoS Computational Biology, 2021 Information flow within and between cells depends significantly on calcium (Ca2+) signaling dynamics. However, the biophysical mechanisms that govern emergent patterns of Ca2+ signaling dynamics at the organ level remain elusive.
Dharsan K. Soundarrajan +4 more
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Calcium signaling and transport machinery: Potential for development of stress tolerance in plants
Current Plant Biology, 2022 Calcium (Ca2+) is an essential macronutrient as well as a second messenger in diverse biological processes in plants. Plants perceive various stimuli which leads to transient increase in cytosolic calcium [Ca2+]cyt levels, resulting in generation of Ca2+
Soma Ghosh +3 more
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