Results 201 to 210 of about 56,978 (263)

Morpho-Functional Responsiveness of Caco-2 Enterocyte-like Monolayers to Insulin in a Pro-Inflammatory Environment. [PDF]

Cells
Mazzei A, Damato M, Iaia I, Maffia M, Schiavone R, Verri T, Barca A.   +6 more
europepmc   +1 more source

Paeonol as a Multi‐Target Therapy for Neurological Disorders: Mechanistic Insights Into Neuroprotection

Immunity, Inflammation and Disease, Volume 14, Issue 8, August 2026.
Paeonol (PNL) exhibits neuroprotective effects by reducing oxidative stress, neuroinflammation, and apoptosis. It enhances antioxidant defenses (SOD and GSH), inhibits pro‐inflammatory pathways (NF‐κB and TLR4), and modulates apoptotic proteins (Bcl‐2 and Bax).
Md. Sakib Al Hasan, Naznin Shahria, Yasin Emon, Mohammad Y. Alshahrani, Emon Mia, Faisal H. Altemani, Rituparna Biswas Suma, Umme Habiba Sumaya, Mohammed Burhan Uddin, Md. Torequl Islam   +9 more
wiley   +1 more source

Effect of Different Prebiotic Saccharides on <i>Listeria monocytogenes</i> Adherence to Human Adenocarcinoma Caco-2 Cell Line. [PDF]

Curr Issues Mol Biol
Kodešová T, Doskočil I, Vlková E, Šubrtová Salmonová H.   +3 more
europepmc   +1 more source

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković, Strahinja Pešić, Marija Novaković, Anđela Dubroja Krstić, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

Remodeling of Bamboo (<i>Phyllostachys edulis</i>) Shoot Polysaccharides by <i>Monascus purpureus</i> Fermentation Enhances Antioxidant Protection in Caco-2 Cells. [PDF]

Foods
Long F, Hu Z, Luo H, Chu Z, Li S, Zhou Y, Li A, Luo F.   +7 more
europepmc   +1 more source

Sevoflurane Alleviates Myocardial Ischemia‐Reperfusion Injury via the HMGB1/ACSL4 Pathway to Suppress Ferroptosis

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Sevoflurane (sevo) alleviates ferroptosis in cardiomyocytes and ameliorates MI/RI symptoms by inhibiting HMGB1 expression, reducing ACSL4 stability, and negatively regulating the HMGB1/ACSL4 signaling pathway. ABSTRACT Sevoflurane (sevo) exhibits cardioprotective effects against myocardial ischemia/reperfusion injury (MIRI); however, its precise ...
Yuliu Mei, Yunfei Cao, Cheng Sheng, Ge Sun, Manhua Zhu   +4 more
wiley   +1 more source

Analysis of the Combined Toxic Effects of AFB1, DON, and OTA Complex Contamination in Caco-2, HK-2, SK-N-SH and HepG2 Cells. [PDF]

Toxins (Basel)
Zhao H, Zhai X, He W, Jing Z, Wang D, Yang J.   +5 more
europepmc   +1 more source

Exposure to polystyrene nanoparticles leads to dysfunction in DNA repair mechanisms in Caco-2 cells. [PDF]

Biol Res
Kustra A, Zając M, Bednarczyk P, Maliszewska-Olejniczak K.   +3 more
europepmc   +1 more source

Integrated Molecular and Functional Analysis of Hop Ethanolic Extract in Caco-2 Cells: Insights into Inflammation, Barrier Function, and Transport. [PDF]

Int J Mol Sci
Verhelst RE, Kruk A.
europepmc   +1 more source

Quercetin ameliorates HIV-1 gp120 protein-induced intestinal barrier dysfunction by inhibiting the activation of the ERK1/2 signaling pathway in a Caco-2 cell model. [PDF]

AIDS Res Ther
Zhu L, Yan J, Wang Q, He X, Xu X, Yang J, Ouyang J.   +6 more
europepmc   +1 more source