Results 31 to 40 of about 97,542,255 (296)
Absorption and Metabolism Characteristics of Rutin in Caco‐2 Cells [PDF]
The Scientific World Journal, 2013 The intestinal absorption and metabolism characteristics of the potentially beneficial polyphenol rutin were studied by measuring the intracellular accumulation and transport of rutin into Caco‐2 cells with the sensitive and reliable analytical method of HPLC‐coupled tandem mass spectrometry.
Xiaofang Zhang +5 more
openaire +3 more sources
The Effects of Retinoic Acid on the Expression of HNF4α and Cdx-2 Genes in Caco-2 Cells as a Model of Intestinal Barrier [PDF]
مجله علمی دانشگاه علوم پزشکی کردستان, 2023 Background and Aim: Retinoic acid (RA) is involved in protecting the intestinal barrier, inducing differentiation, growth and proliferation of epithelial cells.
Mahshad Karambeigi +2 more
doaj
Hepatology, EarlyView., 2022 Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan +22 more
wiley +1 more source
口腔疾病防治, 2023 Objective To investigate the effect of pathogenic bacterium-Porphyromonas gingivalis (P.g) on the proliferation and inflammatory factor expression of human colorectal cancer Caco-2 cells, to determine whether the Janus kinase 2-signal transducers and ...
ZHANG Ruotong , LIU Xiaochen, YE Wei
doaj +1 more source
Hepcidin attenuates zinc efflux in Caco‐2 cells [PDF]
The FASEB Journal, 2016 Hepcidin, a peptide hormone produced by theliver in response to iron loading and inflammation, regulates body iron storesby inhibiting iron transporter function. Zinc also regulates hepcidinexpression; however, the effects of hepcidin on zinc transport and zinctransporter function have not been documented.
Stephen R, Hennigar, James P, McClung
openaire +2 more sources
, 2016 Parental Caco-2 cells (WT, lanes 1) and Caco-2 variants with reduced (KD, lanes 3) or ablated (KO, lanes 3) HAI-2 expression were analyzed by Western blot for matriptase species (A.) and prostasin species (B.).
Ying-Jung J. Lai (704785) +14 more
core +1 more source
TETA-treated Caco-2 quantitative label-free LC-MS/MS
, 2019 Raw and filtered quantitative proteomic profile data sets for 25 μM TETA-treated Caco-2, growth media repleted Caco-2 relative to unexposed control Caco-2 ...
O'Doherty, C (via Mendeley Data) +1 more
core +2 more sources
Determination of drug absorption parameters in Caco-2 cell monolayers with a mathematical model encompassing passive diffusion, carrier-mediated efflux, non-specific binding and phase II metabolism [PDF]
, 2007 Intestinal absorption is required for a sufficiently high bioavailability of drugs administered by the peroral route. Several molecular mechanisms are involved in intestinal absorption and can profoundly influence its magnitude including permeation of ...
Blaser, David Werner
core +1 more source
, 2023 Caco-2 permeability assay is one of the recommended in vitro methods to evaluate drug permeability. It has become the gold standard method to evaluate both the passive and active transport and the absorption of orally administered ...
Hannah Cole
core +1 more source