Results 21 to 30 of about 53,962 (242)
Effect of Cell Generations on t-BHP-induced Oxidative Stress Model of Caco-2 Cells
Shipin gongye ke-ji, 2023 Objective: To investigate the effects of cell passage number on the establishment of an oxidative stress model in human colon adenocarcinoma cells (Caco-2) caused by tert-butyl hydroperoxide (t-BHP).
Jun NI +6 more
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Hepcidin attenuates zinc efflux in Caco‐2 cells [PDF]
The FASEB Journal, 2016 Hepcidin, a peptide hormone produced by theliver in response to iron loading and inflammation, regulates body iron storesby inhibiting iron transporter function. Zinc also regulates hepcidinexpression; however, the effects of hepcidin on zinc transport and zinctransporter function have not been documented.
Stephen R, Hennigar, James P, McClung
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Coumarins permeability in Caco-2 cell model
Journal of Pharmacy and Pharmacology, 2009 AbstractObjectivesThe presence of coumarins in human diet, their multiple pharma***ćological properties and occurrence in various herbal remedies represent significant reasons to explore their membrane permeability, as a first event contributing to coumarins oral bioavailability.
Anna, Galkin +2 more
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Frontiers in Cell and Developmental Biology, 2022 Pin1, a cis/trans isomerase of peptidyl-prolyl peptide bonds, plays a crucial role in the pathogenesis of many human cancers. Although chemical inhibitors of Pin1 show potent antitumor therapeutic properties against various cancers, their effect on ...
Junghoon Kim +3 more
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The intestinal spirochete Brachyspira pilosicoli attaches to cultured Caco-2 cells and induces pathological changes. [PDF]
PLoS ONE, 2009 BACKGROUND:Brachyspira pilosicoli is an anaerobic spirochete that has received relatively little study, partly due to its specialized culture requirements and slow growth. This bacterium colonizes the large intestine of various species, including humans;
Ram Naresh, Yong Song, David J Hampson
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Compartmentalized 3D Tissue Culture Arrays under Controlled Microfluidic Delivery
Scientific Reports, 2017 We demonstrate an in vitro microfluidic cell culture platform that consists of periodic 3D hydrogel compartments with controllable shapes. The microchip is composed of approximately 500 discontinuous collagen gel compartments locally patterned in between
Burcu Gumuscu +4 more
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A metalloproteinase of the disintegrin and metalloproteinases and the ThromboSpondin Motifs 6 as a novel marker for colon cancer: functional experiments [PDF]
Genetics and Molecular Biology, 2020 Herein, we aimed to investigate the functions of ADAMTS6 in colon cancer and its potential mechanism. Based on the data acquired from TCGA database, we revealed that ADAMTS6 was highly expressed in colon cancer tissues, and high expression of ADAMTS6 ...
Yun-Peng Wang +2 more
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Cell association and invasion of Caco-2 cells by Campylobacter jejuni [PDF]
Infection and Immunity, 1994 Adherence and invasion studies were conducted in monolayers of Caco-2 cells. Three-day-old monolayers were inoculated with Campylobacter jejuni 81-176 at a bacterium/cell ratio of 1,000:1. Saturation studies demonstrated time- and dose-dependent saturation curves for C. jejuni cell association and invasion into Caco-2 cells.
R G, Russell, D C, Blake
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Frontiers in Pharmacology, 2023 Background: One of the most significant challenges impeding cancer treatment effectiveness is drug resistance. Combining evolutionary understanding with drug resistance can pave the way for the identification of second-line drug options that can overcome
Nurseda Danisik +2 more
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Apoptosis in astrovirus-infected CaCo-2 cells
Virology, 2004 Cell death processes during human astrovirus replication in CaCo-2 cells and their underlying mechanisms were investigated. Morphological and biochemical alterations typical of apoptosis were analyzed in infected cells using a combination of techniques, including DAPI staining, the sub-G(0)/G(1) technique and the TUNEL assay. The onset of apoptosis was
Guix, Susana +4 more
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