Results 21 to 30 of about 383,770 (381)
The functional activity of E-cadherin controls tumor cell metastasis at multiple steps
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance The expression of E-cadherin has been implicated in tumor metastasis, often as a tumor suppressor, but also as a promoter of growth and metastasis.
T. Na +3 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2022 Tunneling nanotubes (TNTs) are thin membrane tubular structures that interconnect physically separated cells. Growing evidence indicates that TNTs play unique roles in various diseases by facilitating intercellular transfer of signaling and organelles ...
Aoqi Li +3 more
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TGF-β signaling links E-cadherin loss to suppression of nucleotide excision repair. [PDF]
, 2016 E-cadherin is a cell adhesion molecule best known for its function in suppressing tumor progression and metastasis. Here we show that E-cadherin promotes nucleotide excision repair through positively regulating the expression of xeroderma pigmentosum ...
Barcellos-Hoff, MH +3 more
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Molecular cloning and characterization of B-cadherin, a novel chick cadherin. [PDF]
, 1991 Calcium-dependent cell-cell adhesion is mediated in large part by a set of homologous integral membrane glycoproteins termed cadherins. In this report, antibodies to conserved domains in previously described cadherins have been used to isolate cDNAs ...
Napolitano, EW +3 more
core +2 more sources
Quantification of the stiffness and strength of cadherin ectodomain binding with different ions
Theoretical and Applied Mechanics Letters, 2014 The stiffness and strength of extracellular (EC) region of cadherin are proposed to be two important mechanical properties both for cadherin as a mechanotransductor and for the formation of cell-cell adhesion.
Zhiyang Xu, Dechang Li, Ji Baohua
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N-cadherin acts in concert with Slit1-Robo2 signaling in regulating aggregation of placode-derived cranial sensory neurons [PDF]
, 2009 Vertebrate cranial sensory ganglia have a dual origin from the neural crest and ectodermal placodes. In the largest of these, the trigeminal ganglion, Slit1-Robo2 signaling is essential for proper ganglion assembly.
Bronner-Fraser, Marianne +1 more
core +2 more sources
BMC Microbiology, 2011 Background Toxoplasma gondii belongs to a large and diverse group of obligate intracellular parasitic protozoa. Primary culture of mice skeletal muscle cells (SkMC) was employed as a model for experimental toxoplasmosis studies.
Barbosa Helene S +5 more
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Long-term potentiation through calcium-mediated N-Cadherin interaction is tightly controlled by the three-dimensional architecture of the synapse [PDF]
, 2013 Poster presentation: Twenty Second Annual Computational Neuroscience Meeting: CNS*2013. Paris, France. 13-18 July 2013. The synaptic cleft is an extracellular domain that is capable of relaying a presynaptically received electrical signal by diffusive ...
Bunse, Stefanie +3 more
core +1 more source
Genes & Development, 2008 Cancer progression has similarities with the process of epithelial-to-mesenchymal transition (EMT) found during embryonic development, during which cells down-regulate E-cadherin and up-regulate Vimentin expression.
Sun-Mi Park +3 more
semanticscholar +1 more source
Insects, 2012 As key factors in intercellular adhesion processes, cadherins play important roles in a plethora of developmental processes, including gametogenesis. In a previous study on cadherin localization in the gonads of honey bees, performed with heterologous ...
Klaus Hartfelder, Mônica M. Florecki
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