Results 41 to 50 of about 302,660 (297)

Holding it together: when cadherin meets cadherin

open access: yesBiophysical Journal, 2021
Intercellular adhesion is the key to multicellularity, and its malfunction plays an important role in various developmental and disease-related processes. Although it has been intensively studied by both biologists and physicists, a commonly accepted definition of cell-cell adhesion is still being debated.
Arslan, F.N.   +3 more
openaire   +3 more sources

Binding and Synergizing Motif within Coleopteran Cadherin Enhances Cry3Bb Toxicity on the Colorado Potato Beetle and the Lesser Mealworm

open access: yesToxins, 2019
Cry3Bb toxin from Bacillus thuringiensis is an important insecticidal protein due to its potency against coleopteran pests, especially rootworms. Cadherin, a protein in the insect midgut epithelium, is a receptor of Cry toxins; in some insect species ...
Youngjin Park   +4 more
doaj   +1 more source

Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling [PDF]

open access: yes, 2012
The functions of many organs depend on the generation of an epithelium. The transition from a set of loosely connected nonpolarized cells to organized sheets of closely associated polarized epithelial cells requires the assembly of specialized cell ...
Pieters, Tim   +2 more
core   +2 more sources

Cadherins as Matchmakers [PDF]

open access: yesNeuron, 2011
Cadherins implement afferent-target matching in invertebrates, but proof for this concept in mammalian circuits has remained elusive. Two new studies in this issue of Neuron show that cadherin-6 mediates retinal ganglion cell target selection and that cadherin-9 promotes synapse specificity in the hippocampus.
Rebsam, Alexandra, Mason, Carol A.
openaire   +2 more sources

Matrix metalloproteinases, synaptic injury, and multiple sclerosis

open access: yesFrontiers in Psychiatry, 2010
Multiple sclerosis (MS) is a disease of the central nervous system in which immune mediated damage to myelin is characteristic. For an overview of this condition and its pathophysiology, please refer to one of many excellent published reviews. To follow,
Arek Szklarczyk, Katherine eConant
doaj   +1 more source

Effects of systemic administration of HESA-A on the expression of cyclin D1 and EGFR and E-cadherin in the induced tongue dysplasia in rats [PDF]

open access: yesJournal of Dental Research, Dental Clinics, Dental Prospects, 2017
Background. HESA-A has herbal and marine bases, containing minerals and rare elements such as Zr, Cr, Ga, Mn, Mg, Ca, Sr, Cu, Ti, etc. Its mechanism of action includes antioxidant, antiinflammatory and adjustment of the immune system.
Shirin Fattahi   +5 more
doaj   +1 more source

T-cadherin expression alternates with migrating neural crest cells in the trunk of the avian embryo [PDF]

open access: yes, 1991
Trunk neural crest cells and motor axons move in a segmental fashion through the rostral (anterior) half of each somitic sclerotome, avoiding the caudal (posterior) half.
Bronner-Fraser, Marianne   +1 more
core  

Functions of p120ctn in development and disease [PDF]

open access: yes, 2012
p120 catenin (p120ctn), a component of the cadherin-catenin complex, was the first member to be identified in a most interesting subfamily of the Armadillo family. Several p120ctn isoforms are generated by alternative splicing.
Pieters, Tim   +2 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Astrocyte Mechano-Activation by High-Rate Overpressure Involves Alterations in Structural and Junctional Proteins

open access: yesFrontiers in Neurology, 2019
Primary blast neurotrauma represents a unique injury paradigm characterized by high-rate overpressure effects on brain tissue. One major hallmark of blast neurotrauma is glial reactivity, notably prolonged astrocyte activation. This cellular response has
Nora Hlavac   +2 more
doaj   +1 more source

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