Results 21 to 30 of about 182,358 (260)

Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity

open access: yesFrontiers in Cell and Developmental Biology, 2023
Cadherin EGF LAG seven-pass G-type receptor (Celsr) proteins 1-3 comprise a subgroup of adhesion GPCRs whose functions range from planar cell polarity (PCP) signaling to axon pathfinding and ciliogenesis. Like its Drosophila ortholog, Flamingo, mammalian
Lena P. Basta   +6 more
doaj   +1 more source

Microscopic pulmonary tumor embolism from adenocarcinoma of the prostate

open access: yesIJU Case Reports, 2020
Introduction Microscopic pulmonary tumor embolisms from prostate cancer are extremely rare. In this case of prostate cancer, microscopic pulmonary tumor embolism developed during androgen deprivation therapy.
Tatsuya Hattori   +6 more
doaj   +1 more source

The Art of Mast Cell Adhesion

open access: yesCells, 2020
Cell adhesion is one of the basic phenomena occurring in a living organism, affecting many other processes such as proliferation, differentiation, migration, or cell viability.
Joanna Pastwińska   +4 more
doaj   +1 more source

Dynamics of the Actin Cytoskeleton at Adhesion Complexes

open access: yesBiology, 2021
The shape of cells is altered to allow cells to adapt to their changing environments, including responding to internally generated and externally applied force. Force is sensed by cell surface adhesion proteins that are enriched in sites where cells bind
Nicholas M. Cronin, Kris A. DeMali
doaj   +1 more source

Dynamic Expression and Functional Implications of the Cell Polarity Gene, Dchs1, During Cardiac Development

open access: yesCells
Intercellular interactions among cardiac cell populations are essential for cardiac morphogenesis, yet the molecular mechanisms orchestrating these events remain incompletely understood.
Kathryn Byerly   +15 more
doaj   +1 more source

Cadherin Protein Is Involved in the Action of Bacillus thuringiensis Cry1Ac Toxin in Ostrinia furnacalis

open access: yesToxins, 2021
Transgenic crops expressing Bacillus thuringiensis (Bt) insecticidal proteins have been extensively planted for insect pest control, but the evolution of Bt resistance in target pests threatens the sustainability of this approach.
Wenzhong Jin   +4 more
doaj   +1 more source

Sirtuin 7 Promotes Mesenchymal to Epithelial Transition by β-Catenin Redistribution and Stabilization

open access: yesFrontiers in Oncology, 2020
SIRT7 belongs to the family of “NAD+ dependent deacetylases” called Sirtuins. In the present work we report a novel role of SIRT7 in regulating cellular polarity.
Shashi Kiran   +4 more
doaj   +1 more source

Desmoglein-2 as a cancer modulator: friend or foe?

open access: yesFrontiers in Oncology, 2023
Desmoglein-2 (DSG2) is a calcium-binding single pass transmembrane glycoprotein and a member of the large cadherin family. Until recently, DSG2 was thought to only function as a cell adhesion protein embedded within desmosome junctions designed to enable
Kay K. Myo Min   +13 more
doaj   +1 more source

Niche Cadherins Control the Quiescence-to-Activation Transition in Muscle Stem Cells

open access: yesCell Reports, 2017
Many adult stem cells display prolonged quiescence, promoted by cues from their niche. Upon tissue damage, a coordinated transition to the activated state is required because non-physiological breaks in quiescence often lead to stem cell depletion and ...
Aviva J. Goel   +4 more
doaj   +1 more source

Constitutive Occurrence of E:N-cadherin Heterodimers in Adherens Junctions of Hepatocytes and Derived Tumors

open access: yesCells, 2022
Cell–cell junctions are pivotal for embryogenesis and tissue homeostasis but also play a major role in tumorigenesis, tumor invasion, and metastasis. E-cadherin (CDH1) and N-cadherin (CDH2) are two adherens junction’s transmembrane glycoproteins with ...
Tiemo Sven Gerber   +10 more
doaj   +1 more source

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