Results 11 to 20 of about 284,314 (352)

Mutations in a Novel Cadherin Gene Associated with Bt Resistance in Helicoverpa zea

open access: yesG3: Genes, Genomes, Genetics, 2020
Transgenic corn and cotton produce crystalline (Cry) proteins derived from the soil bacterium Bacillus thuringiensis (Bt) that are toxic to lepidopteran larvae. Helicoverpa zea, a key pest of corn and cotton in the U.S., has evolved widespread resistance
Megan L. Fritz   +4 more
doaj   +1 more source

Differential Displacement of Classical Cadherins by VE-Cadherin [PDF]

open access: yesCell Communication & Adhesion, 2002
VE-cadherin is an endothelial cell-specific, type II classical cadherin that plays an important role in permeability, vasculogenesis, and vascular remodeling. Endothelial cells express equal levels of VE- and N-cadherin; VE-cadherin is present injunctions while N-cadherin is diffusely expressed over the surface of the cell.
Meena, Jaggi   +2 more
openaire   +2 more sources

Mechanical properties of tunneling nanotube and its mechanical stability in human embryonic kidney cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
Tunneling nanotubes (TNTs) are thin membrane tubular structures that interconnect physically separated cells. Growing evidence indicates that TNTs play unique roles in various diseases by facilitating intercellular transfer of signaling and organelles ...
Aoqi Li   +3 more
doaj   +1 more source

Design of a Photoswitchable Cadherin [PDF]

open access: yesJournal of the American Chemical Society, 2013
There is a growing interest in engineering proteins whose function can be controlled with the spatial and temporal precision of light. Here, we present a novel example of a functional light-triggered switch in the Ca-dependent cell-cell adhesion protein E-cadherin, created using a mechanism-based design strategy. We report an 18-fold change in apparent
Kortemme, Tanja   +3 more
openaire   +4 more sources

Differential Regulation of Growth-Promoting Signalling Pathways by E-Cadherin [PDF]

open access: yes, 2010
Background: Despite the well-documented association between loss of E-cadherin and carcinogenesis, as well as the link between restoration of its expression and suppression of proliferation in carcinoma cells, the ability of E-cadherin to modulate growth-
Dawn C Walker   +18 more
core   +1 more source

Quantification of the stiffness and strength of cadherin ectodomain binding with different ions

open access: yesTheoretical and Applied Mechanics Letters, 2014
The stiffness and strength of extracellular (EC) region of cadherin are proposed to be two important mechanical properties both for cadherin as a mechanotransductor and for the formation of cell-cell adhesion.
Zhiyang Xu, Dechang Li, Ji Baohua
doaj   +1 more source

Toxoplasma gondii down modulates cadherin expression in skeletal muscle cells inhibiting myogenesis

open access: yesBMC Microbiology, 2011
Background Toxoplasma gondii belongs to a large and diverse group of obligate intracellular parasitic protozoa. Primary culture of mice skeletal muscle cells (SkMC) was employed as a model for experimental toxoplasmosis studies.
Barbosa Helene S   +5 more
doaj   +1 more source

Modulatory effects of T-cadherin on cell behavior and growth factor receptor activity in carcinoma cells [PDF]

open access: yes, 2014
Cancer is a major health problem. Epidermal growth factor receptor (EGFR) pathway plays an important role in cancer progression. EGFR-targeted anti-cancer drugs are being developed to improve anti-cancer therapy.
Maslova, Kseniya
core   +1 more source

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2.

open access: yesGenes & Development, 2008
Cancer progression has similarities with the process of epithelial-to-mesenchymal transition (EMT) found during embryonic development, during which cells down-regulate E-cadherin and up-regulate Vimentin expression.
Sun-Mi Park   +3 more
semanticscholar   +1 more source

Unconventional Cadherin Localization in Honey Bee Gonads Revealed Through Domain-Specific Apis mellifera E- and N-Cadherin Antibodies Indicates Alternative Functions

open access: yesInsects, 2012
As key factors in intercellular adhesion processes, cadherins play important roles in a plethora of developmental processes, including gametogenesis. In a previous study on cadherin localization in the gonads of honey bees, performed with heterologous ...
Klaus Hartfelder, Mônica M. Florecki
doaj   +1 more source

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