Results 11 to 20 of about 302,660 (297)

Mutations in a Novel Cadherin Gene Associated with Bt Resistance in Helicoverpa zea

open access: yesG3: Genes, Genomes, Genetics, 2020
Transgenic corn and cotton produce crystalline (Cry) proteins derived from the soil bacterium Bacillus thuringiensis (Bt) that are toxic to lepidopteran larvae. Helicoverpa zea, a key pest of corn and cotton in the U.S., has evolved widespread resistance
Megan L. Fritz   +4 more
doaj   +1 more source

Mechanical properties of tunneling nanotube and its mechanical stability in human embryonic kidney cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
Tunneling nanotubes (TNTs) are thin membrane tubular structures that interconnect physically separated cells. Growing evidence indicates that TNTs play unique roles in various diseases by facilitating intercellular transfer of signaling and organelles ...
Aoqi Li   +3 more
doaj   +1 more source

TGF-β signaling links E-cadherin loss to suppression of nucleotide excision repair. [PDF]

open access: yes, 2016
E-cadherin is a cell adhesion molecule best known for its function in suppressing tumor progression and metastasis. Here we show that E-cadherin promotes nucleotide excision repair through positively regulating the expression of xeroderma pigmentosum ...
Barcellos-Hoff, MH   +3 more
core   +1 more source

Quantification of the stiffness and strength of cadherin ectodomain binding with different ions

open access: yesTheoretical and Applied Mechanics Letters, 2014
The stiffness and strength of extracellular (EC) region of cadherin are proposed to be two important mechanical properties both for cadherin as a mechanotransductor and for the formation of cell-cell adhesion.
Zhiyang Xu, Dechang Li, Ji Baohua
doaj   +1 more source

Molecular cloning and characterization of B-cadherin, a novel chick cadherin. [PDF]

open access: yes, 1991
Calcium-dependent cell-cell adhesion is mediated in large part by a set of homologous integral membrane glycoproteins termed cadherins. In this report, antibodies to conserved domains in previously described cadherins have been used to isolate cDNAs ...
Napolitano, EW   +3 more
core   +2 more sources

Toxoplasma gondii down modulates cadherin expression in skeletal muscle cells inhibiting myogenesis

open access: yesBMC Microbiology, 2011
Background Toxoplasma gondii belongs to a large and diverse group of obligate intracellular parasitic protozoa. Primary culture of mice skeletal muscle cells (SkMC) was employed as a model for experimental toxoplasmosis studies.
Barbosa Helene S   +5 more
doaj   +1 more source

Unconventional Cadherin Localization in Honey Bee Gonads Revealed Through Domain-Specific Apis mellifera E- and N-Cadherin Antibodies Indicates Alternative Functions

open access: yesInsects, 2012
As key factors in intercellular adhesion processes, cadherins play important roles in a plethora of developmental processes, including gametogenesis. In a previous study on cadherin localization in the gonads of honey bees, performed with heterologous ...
Klaus Hartfelder, Mônica M. Florecki
doaj   +1 more source

The Cadherin Protein Is Not Involved in Susceptibility to Bacillus thuringiensis Cry1Ab or Cry1Fa Toxins in Spodoptera frugiperda

open access: yesToxins, 2020
It is well known that insect larval midgut cadherin protein serves as a receptor of Bacillus thuringiensis (Bt) crystal Cry1Ac or Cry1Ab toxins, since structural mutations and downregulation of cad gene expression are linked with resistance to Cry1Ac ...
Jianfeng Zhang   +9 more
doaj   +1 more source

P-cadherin counteracts myosin II-B function : implications in melanoma progression [PDF]

open access: yes, 2010
BACKGROUND: Malignant transformation of melanocytes is frequently attended by a switch in cadherin expression profile as shown for E- and N-cadherin. For P-cadherin, downregulation in metastasizing melanoma has been demonstrated, and over-expression of P-
Jacobs, Koen   +6 more
core   +3 more sources

Aedes cadherin receptor that mediates Bacillus thuringiensis Cry11A toxicity is essential for mosquito development. [PDF]

open access: yes, 2020
Aedes cadherin (AaeCad, AAEL024535) has been characterized as a receptor for Bacillus thuringiensis subsp. israelensis (Bti) Cry11A toxins. However, its role in development is still unknown.
Aimanova, Karly G   +2 more
core   +2 more sources

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